definition
type: AnnotationProperty

expand assertion to
type: AnnotationProperty

term replaced by
type: AnnotationProperty

never_in_taxon
type: AnnotationProperty
expand assertion to: Class: ?X DisjointWith: RO_0002162 some ?Y
database_cross_reference: RO:0002161
has_obo_namespace: external
id: never_in_taxon
is class level: true
is metadata tag: true
shorthand: never_in_taxon

goantislim grouping
type: AnnotationProperty
comment: Grouping classes that can be excluded
sub property of: subset_property

gocheck do not annotate
type: AnnotationProperty
comment: Term not to be used for direct annotation
sub property of: subset_property

gocheck do not manually annotate
type: AnnotationProperty
comment: Term not to be used for direct manual annotation
sub property of: subset_property

goslim aspergillus
type: AnnotationProperty
comment: Aspergillus GO slim
sub property of: subset_property

goslim candida
type: AnnotationProperty
comment: Candida GO slim
sub property of: subset_property

goslim chembl
type: AnnotationProperty
comment: ChEMBL protein targets summary
sub property of: subset_property

goslim generic
type: AnnotationProperty
comment: Generic GO slim
sub property of: subset_property

goslim goa
type: AnnotationProperty
comment: GOA and proteome slim
sub property of: subset_property

goslim metagenomics
type: AnnotationProperty
comment: Metagenomics GO slim
sub property of: subset_property

goslim pir
type: AnnotationProperty
comment: PIR GO slim
sub property of: subset_property

goslim plant
type: AnnotationProperty
comment: Plant GO slim
sub property of: subset_property

goslim pombe
type: AnnotationProperty
comment: Fission yeast GO slim
sub property of: subset_property

goslim synapse
type: AnnotationProperty
comment: synapse GO slim
sub property of: subset_property

goslim virus
type: AnnotationProperty
comment: Viral GO slim
sub property of: subset_property

goslim yeast
type: AnnotationProperty
comment: Yeast GO slim
sub property of: subset_property

gosubset prok
type: AnnotationProperty
comment: Prokaryotic GO subset
sub property of: subset_property

mf needs review
type: AnnotationProperty
comment: Catalytic activity terms in need of attention
sub property of: subset_property

Systematic synonym
type: AnnotationProperty
has_scope: has_exact_synonym
sub property of: synonym_type_property

termgenie unvetted
type: AnnotationProperty
comment: Terms created by TermGenie that do not follow a template and require additional vetting by editors
sub property of: subset_property

virus checked
type: AnnotationProperty
comment: Viral overhaul terms
sub property of: subset_property

subset_property
type: AnnotationProperty

synonym_type_property
type: AnnotationProperty

consider
type: AnnotationProperty

has_alternative_id
type: AnnotationProperty

has_broad_synonym
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty

has_narrow_synonym
type: AnnotationProperty

has_obo_format_version
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

has_scope
type: AnnotationProperty

has_synonym_type
type: AnnotationProperty

in_subset
type: AnnotationProperty

shorthand
type: AnnotationProperty

part of
type: ObjectProperty
inverse of: has_part
type: TransitiveProperty
database_cross_reference: BFO:0000050
has_obo_namespace: external
id: part_of
shorthand: part_of

has_part
type: ObjectProperty
type: TransitiveProperty
database_cross_reference: BFO:0000051
has_obo_namespace: external
id: has_part
shorthand: has_part

occurs in
type: ObjectProperty
property chain axiom: part of
database_cross_reference: BFO:0000066
has_obo_namespace: external
id: occurs_in
shorthand: occurs_in

starts_during
type: ObjectProperty
database_cross_reference: RO:0002091
has_obo_namespace: external
id: starts_during
shorthand: starts_during

happens_during
type: ObjectProperty
sub property of: ends_during
type: TransitiveProperty
database_cross_reference: RO:0002092
has_obo_namespace: external
id: happens_during
shorthand: happens_during

ends_during
type: ObjectProperty
database_cross_reference: RO:0002093
has_obo_namespace: external
id: ends_during
shorthand: ends_during

regulates
type: ObjectProperty
type: TransitiveProperty
property chain axiom: part of
database_cross_reference: RO:0002211
has_obo_namespace: external
id: regulates
shorthand: regulates

negatively regulates
type: ObjectProperty
sub property of: regulates
property chain axiom: part of
database_cross_reference: RO:0002212
has_obo_namespace: external
id: negatively_regulates
shorthand: negatively_regulates

positively regulates
type: ObjectProperty
sub property of: regulates
property chain axiom: negatively regulates
property chain axiom: part of
database_cross_reference: RO:0002213
has_obo_namespace: external
id: positively_regulates
shorthand: positively_regulates

ribosomal subunit export from nucleus
type: Class
subclass of: nuclear transport
subclass of: Restriction
  on property: has_part
  some values from: nucleobase-containing compound transport
subclass of: Restriction
  on property: has_part
  some values from: nuclear transport
definition: The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.
has_exact_synonym: ribosomal subunit export from cell nucleus
has_exact_synonym: ribosomal subunit export out of nucleus
has_exact_synonym: ribosomal subunit transport from nucleus to cytoplasm
has_exact_synonym: ribosomal subunit-nucleus export
has_obo_namespace: biological_process
has_related_synonym: ribosome export from nucleus
id: GO:0000054
in_subset: goslim yeast

Axiom
annotated source: ribosomal subunit export from nucleus
annotated property: definition
annotated target: The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.
database_cross_reference: GOC:ai

Axiom
annotated source: ribosomal subunit export from nucleus
annotated property: has_exact_synonym
annotated target: ribosomal subunit export from cell nucleus
database_cross_reference: GOC:mah

Axiom
annotated source: ribosomal subunit export from nucleus
annotated property: has_exact_synonym
annotated target: ribosomal subunit export out of nucleus
database_cross_reference: GOC:mah

Axiom
annotated source: ribosomal subunit export from nucleus
annotated property: has_exact_synonym
annotated target: ribosomal subunit transport from nucleus to cytoplasm
database_cross_reference: GOC:mah

Axiom
annotated source: ribosomal subunit export from nucleus
annotated property: has_exact_synonym
annotated target: ribosomal subunit-nucleus export
database_cross_reference: GOC:mah

Axiom
annotated source: ribosomal subunit export from nucleus
annotated property: has_related_synonym
annotated target: ribosome export from nucleus
database_cross_reference: GOC:mah
database_cross_reference: GOC:rb

mitotic cell cycle
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: has_part
  some values from: organelle fission
definition: Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
database_cross_reference: Reactome:REACT_100451
database_cross_reference: Reactome:REACT_104035
database_cross_reference: Reactome:REACT_104195
database_cross_reference: Reactome:REACT_105856
database_cross_reference: Reactome:REACT_108233
database_cross_reference: Reactome:REACT_152
database_cross_reference: Reactome:REACT_28464
database_cross_reference: Reactome:REACT_28953
database_cross_reference: Reactome:REACT_33388
database_cross_reference: Reactome:REACT_53493
database_cross_reference: Reactome:REACT_79085
database_cross_reference: Reactome:REACT_84794
database_cross_reference: Reactome:REACT_85137
database_cross_reference: Reactome:REACT_85950
database_cross_reference: Reactome:REACT_90332
database_cross_reference: Reactome:REACT_90846
database_cross_reference: Reactome:REACT_96281
database_cross_reference: Reactome:REACT_97744
database_cross_reference: Reactome:REACT_98208
has_obo_namespace: biological_process
id: GO:0000278
in_subset: goslim yeast

Axiom
annotated source: mitotic cell cycle
annotated property: definition
annotated target: Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
database_cross_reference: GOC:mah
database_cross_reference: ISBN:0815316194
database_cross_reference: Reactome:69278

Cell Cycle, Mitotic, Taeniopygia guttata
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_100451

Cell Cycle, Mitotic, Sus scrofa
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_104035

Cell Cycle, Mitotic, Canis familiaris
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_104195

Cell Cycle, Mitotic, Danio rerio
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_105856

Cell Cycle, Mitotic, Saccharomyces cerevisiae
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_108233

Cell Cycle, Mitotic, Homo sapiens
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_152

Cell Cycle, Mitotic, Xenopus tropicalis
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_28464

Cell Cycle, Mitotic, Bos taurus
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_28953

Cell Cycle, Mitotic, Rattus norvegicus
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_33388

Cell Cycle, Mitotic, Plasmodium falciparum
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_53493

Cell Cycle, Mitotic, Schizosaccharomyces pombe
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_79085

Cell Cycle, Mitotic, Caenorhabditis elegans
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_84794

Cell Cycle, Mitotic, Gallus gallus
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_85137

Cell Cycle, Mitotic, Arabidopsis thaliana
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_85950

Cell Cycle, Mitotic, Mus musculus
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_90332

Cell Cycle, Mitotic, Oryza sativa
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_90846

Cell Cycle, Mitotic, Drosophila melanogaster
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_96281

Cell Cycle, Mitotic, Dictyostelium discoideum
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_97744

Cell Cycle, Mitotic, Mycobacterium tuberculosis
type: Axiom
annotated source: mitotic cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_98208

conjugation
type: Class
subclass of: biological_process
definition: The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.
database_cross_reference: Wikipedia:Conjugation
has_obo_namespace: biological_process
id: GO:0000746
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: conjugation
annotated property: definition
annotated target: The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.
database_cross_reference: GOC:elh

cell morphogenesis
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The developmental process in which the size or shape of a cell is generated and organized.
has_alternative_id: GO:0007148
has_alternative_id: GO:0045790
has_alternative_id: GO:0045791
has_exact_synonym: cellular morphogenesis
has_obo_namespace: biological_process
id: GO:0000902
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cell morphogenesis
annotated property: definition
annotated target: The developmental process in which the size or shape of a cell is generated and organized.
database_cross_reference: GOC:clt
database_cross_reference: GOC:dph
database_cross_reference: GOC:go_curators
database_cross_reference: GOC:tb

cytokinesis
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
subclass of: Restriction
  on property: has_part
  some values from: biological_process
definition: The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
has_alternative_id: GO:0007104
has_alternative_id: GO:0016288
has_alternative_id: GO:0033205
database_cross_reference: Reactome:REACT_101918
database_cross_reference: Reactome:REACT_108805
database_cross_reference: Reactome:REACT_1932
database_cross_reference: Reactome:REACT_30667
database_cross_reference: Reactome:REACT_32636
database_cross_reference: Reactome:REACT_78494
database_cross_reference: Reactome:REACT_84722
database_cross_reference: Reactome:REACT_87726
database_cross_reference: Reactome:REACT_92849
database_cross_reference: Reactome:REACT_93374
database_cross_reference: Reactome:REACT_94382
database_cross_reference: Reactome:REACT_98952
database_cross_reference: Reactome:REACT_99118
database_cross_reference: Wikipedia:Cytokinesis
has_exact_synonym: cell cycle cytokinesis
has_exact_synonym: cytokinesis involved in cell cycle
has_obo_namespace: biological_process
id: GO:0000910
in_subset: gocheck do not manually annotate
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that when annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'FtsZ-dependent cytokinesis ; GO:0043093' or Cdv-dependent cytokinesis ; GO:0061639. Also, note that cytokinesis does not necessarily result in physical separation and detachment of the two daughter cells from each other.

Axiom
annotated source: cytokinesis
annotated property: definition
annotated target: The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
database_cross_reference: GOC:mtg_cell_cycle

Mitotic Telophase /Cytokinesis, Mus musculus
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_101918

Mitotic Telophase /Cytokinesis, Dictyostelium discoideum
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_108805

Mitotic Telophase /Cytokinesis, Homo sapiens
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_1932

Mitotic Telophase /Cytokinesis, Schizosaccharomyces pombe
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_30667

Mitotic Telophase /Cytokinesis, Bos taurus
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_32636

Mitotic Telophase /Cytokinesis, Danio rerio
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_78494

Mitotic Telophase /Cytokinesis, Gallus gallus
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_84722

Mitotic Telophase /Cytokinesis, Xenopus tropicalis
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_87726

Mitotic Telophase /Cytokinesis, Taeniopygia guttata
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_92849

Mitotic Telophase /Cytokinesis, Canis familiaris
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_93374

Mitotic Telophase /Cytokinesis, Drosophila melanogaster
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_94382

Mitotic Telophase /Cytokinesis, Rattus norvegicus
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_98952

Mitotic Telophase /Cytokinesis, Caenorhabditis elegans
type: Axiom
annotated source: cytokinesis
annotated property: database_cross_reference
annotated target: Reactome:REACT_99118

Axiom
annotated source: cytokinesis
annotated property: has_exact_synonym
annotated target: cytokinesis involved in cell cycle
database_cross_reference: GOC:dph
database_cross_reference: GOC:tb

transcription factor activity, protein binding
type: Class
subclass of: molecular_function
subclass of: Restriction
  on property: part of
  some values from: biological_process
subclass of: Restriction
  on property: has_part
  some values from: molecular_function
definition: Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
created by: kchris
creation date: 2010-08-10T04:03:22Z
has_broad_synonym: transcription factor activity
has_exact_synonym: protein binding transcription factor activity
has_obo_namespace: molecular_function
id: GO:0000988
in_subset: gocheck do not manually annotate
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. This term does not provide specificity with respect to the type of protein binding, e.g. transcription factor binding or RNA polymerase binding. Please use a child term that provides that specificity or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

Axiom
annotated source: transcription factor activity, protein binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
database_cross_reference: GOC:txnOH

nucleic acid binding transcription factor activity
type: Class
subclass of: molecular_function
subclass of: Restriction
  on property: part of
  some values from: biological_process
subclass of: Restriction
  on property: has_part
  some values from: molecular_function
definition: Interacting selectively and non-covalently with a DNA or RNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
created by: kchris
creation date: 2010-10-21T04:37:54Z
has_broad_synonym: transcription factor activity
has_obo_namespace: molecular_function
id: GO:0001071
in_subset: gocheck do not manually annotate
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. This term does not provide specificity with respect to the type of nucleic acid binding, e.g. RNA or DNA. Please use a child term that provides that specificity or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

Axiom
annotated source: nucleic acid binding transcription factor activity
annotated property: definition
annotated target: Interacting selectively and non-covalently with a DNA or RNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
database_cross_reference: GOC:txnOH

invasive growth in response to glucose limitation
type: Class
subclass of: biological_process
definition: A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
has_obo_namespace: biological_process
has_related_synonym: colony morphology
id: GO:0001403
in_subset: goslim yeast
comment: Note that this term should not be used to describe the invasion of host tissues by pathogenic organisms, which is described by the biological process term 'entry into host ; GO:0044409', nor should it be used to describe growth of diseased cells of an organism into the surrounding normal tissue, which is outside of the scope of GO.

Axiom
annotated source: invasive growth in response to glucose limitation
annotated property: definition
annotated target: A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
database_cross_reference: GOC:mcc
database_cross_reference: PMID:9728395

cytoplasmic translation
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: has_part
  some values from: translational elongation
definition: The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
created by: hjd
creation date: 2011-06-09T03:11:53Z
has_obo_namespace: biological_process
id: GO:0002181
in_subset: goslim pombe
in_subset: goslim yeast
comment: Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms.

Axiom
annotated source: cytoplasmic translation
annotated property: definition
annotated target: The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
database_cross_reference: GOC:hjd

molecular_function
type: Class
definition: Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
has_alternative_id: GO:0005554
has_exact_synonym: molecular function
has_obo_namespace: molecular_function
id: GO:0003674
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. Note that when this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this.

Axiom
annotated source: molecular_function
annotated property: definition
annotated target: Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
database_cross_reference: GOC:go_curators

DNA binding
type: Class
subclass of: molecular_function
definition: Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
has_narrow_synonym: plasmid binding
has_obo_namespace: molecular_function
has_related_synonym: microtubule/chromatin interaction
id: GO:0003677
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: DNA binding
annotated property: definition
annotated target: Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
database_cross_reference: GOC:dph
database_cross_reference: GOC:jl
database_cross_reference: GOC:tb
database_cross_reference: GOC:vw

chromatin binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
has_broad_synonym: lamin/chromatin binding
has_narrow_synonym: nuclear membrane vesicle binding to chromatin
has_obo_namespace: molecular_function
has_related_synonym: microtubule/chromatin interaction
id: GO:0003682
in_subset: goslim chembl
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast

Axiom
annotated source: chromatin binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
database_cross_reference: GOC:jl
database_cross_reference: ISBN:0198506732
database_cross_reference: PMID:20404130

RNA binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
database_cross_reference: Reactome:REACT_101703
database_cross_reference: Reactome:REACT_103323
database_cross_reference: Reactome:REACT_106430
database_cross_reference: Reactome:REACT_107757
database_cross_reference: Reactome:REACT_108232
database_cross_reference: Reactome:REACT_108368
database_cross_reference: Reactome:REACT_109723
database_cross_reference: Reactome:REACT_12458
database_cross_reference: Reactome:REACT_29965
database_cross_reference: Reactome:REACT_77167
database_cross_reference: Reactome:REACT_78197
database_cross_reference: Reactome:REACT_87164
database_cross_reference: Reactome:REACT_89329
database_cross_reference: Reactome:REACT_90531
database_cross_reference: Reactome:REACT_98683
has_obo_namespace: molecular_function
id: GO:0003723
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: RNA binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
database_cross_reference: GOC:mah

Exportin-5 recognizes 3' overhang of pre-miRNA, Xenopus tropicalis
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_101703

Exportin-5 recognizes 3' overhang of pre-miRNA, Dictyostelium discoideum
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_103323

Exportin-5 recognizes 3' overhang of pre-miRNA, Mus musculus
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_106430

Exportin-5 recognizes 3' overhang of pre-miRNA, Drosophila melanogaster
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_107757

Exportin-5 recognizes 3' overhang of pre-miRNA, Oryza sativa
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_108232

Exportin-5 recognizes 3' overhang of pre-miRNA, Saccharomyces cerevisiae
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_108368

Exportin-5 recognizes 3' overhang of pre-miRNA, Arabidopsis thaliana
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_109723

Exportin-5 recognizes 3' overhang of pre-miRNA, Homo sapiens
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_12458

Exportin-5 recognizes 3' overhang of pre-miRNA, Canis familiaris
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_29965

Exportin-5 recognizes 3' overhang of pre-miRNA, Gallus gallus
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_77167

Exportin-5 recognizes 3' overhang of pre-miRNA, Sus scrofa
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_78197

Exportin-5 recognizes 3' overhang of pre-miRNA, Schizosaccharomyces pombe
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_87164

Exportin-5 recognizes 3' overhang of pre-miRNA, Rattus norvegicus
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_89329

Exportin-5 recognizes 3' overhang of pre-miRNA, Danio rerio
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_90531

Exportin-5 recognizes 3' overhang of pre-miRNA, Taeniopygia guttata
type: Axiom
annotated source: RNA binding
annotated property: database_cross_reference
annotated target: Reactome:REACT_98683

mRNA binding
type: Class
subclass of: RNA binding
definition: Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
has_obo_namespace: molecular_function
id: GO:0003729
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: mRNA binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
database_cross_reference: GOC:kmv
database_cross_reference: SO:0000234

structural constituent of ribosome
type: Class
subclass of: structural molecule activity
definition: The action of a molecule that contributes to the structural integrity of the ribosome.
has_alternative_id: GO:0003736
has_alternative_id: GO:0003737
has_alternative_id: GO:0003738
has_alternative_id: GO:0003739
has_alternative_id: GO:0003740
has_alternative_id: GO:0003741
has_alternative_id: GO:0003742
has_broad_synonym: ribosomal protein
has_obo_namespace: molecular_function
has_related_synonym: ribosomal RNA
id: GO:0003735
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that this term may be used to annotate ribosomal RNAs as well as ribosomal proteins.

Axiom
annotated source: structural constituent of ribosome
annotated property: definition
annotated target: The action of a molecule that contributes to the structural integrity of the ribosome.
database_cross_reference: GOC:mah

GTPase activity
type: Class
subclass of: hydrolase activity
definition: Catalysis of the reaction: GTP + H2O = GDP + phosphate.
has_broad_synonym: hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
database_cross_reference: RHEA:19672
database_cross_reference: Reactome:REACT_100432
database_cross_reference: Reactome:REACT_100708
database_cross_reference: Reactome:REACT_101121
database_cross_reference: Reactome:REACT_101520
database_cross_reference: Reactome:REACT_101563
database_cross_reference: Reactome:REACT_101678
database_cross_reference: Reactome:REACT_102040
database_cross_reference: Reactome:REACT_102208
database_cross_reference: Reactome:REACT_102307
database_cross_reference: Reactome:REACT_102371
database_cross_reference: Reactome:REACT_102510
database_cross_reference: Reactome:REACT_102532
database_cross_reference: Reactome:REACT_103518
database_cross_reference: Reactome:REACT_104081
database_cross_reference: Reactome:REACT_104477
database_cross_reference: Reactome:REACT_104739
database_cross_reference: Reactome:REACT_105323
database_cross_reference: Reactome:REACT_105697
database_cross_reference: Reactome:REACT_105708
database_cross_reference: Reactome:REACT_105854
database_cross_reference: Reactome:REACT_106121
database_cross_reference: Reactome:REACT_106217
database_cross_reference: Reactome:REACT_106301
database_cross_reference: Reactome:REACT_106528
database_cross_reference: Reactome:REACT_107176
database_cross_reference: Reactome:REACT_107306
database_cross_reference: Reactome:REACT_107730
database_cross_reference: Reactome:REACT_107820
database_cross_reference: Reactome:REACT_108363
database_cross_reference: Reactome:REACT_108653
database_cross_reference: Reactome:REACT_108825
database_cross_reference: Reactome:REACT_108837
database_cross_reference: Reactome:REACT_109360
database_cross_reference: Reactome:REACT_109897
database_cross_reference: Reactome:REACT_110131
database_cross_reference: Reactome:REACT_110443
database_cross_reference: Reactome:REACT_110557
database_cross_reference: Reactome:REACT_110859
database_cross_reference: Reactome:REACT_110879
database_cross_reference: Reactome:REACT_110931
database_cross_reference: Reactome:REACT_111994
database_cross_reference: Reactome:REACT_112104
database_cross_reference: Reactome:REACT_112254
database_cross_reference: Reactome:REACT_112389
database_cross_reference: Reactome:REACT_112587
database_cross_reference: Reactome:REACT_112651
database_cross_reference: Reactome:REACT_112671
database_cross_reference: Reactome:REACT_113058
database_cross_reference: Reactome:REACT_113209
database_cross_reference: Reactome:REACT_113727
database_cross_reference: Reactome:REACT_113832
database_cross_reference: Reactome:REACT_113952
database_cross_reference: Reactome:REACT_113954
database_cross_reference: Reactome:REACT_114148
database_cross_reference: Reactome:REACT_114153
database_cross_reference: Reactome:REACT_114188
database_cross_reference: Reactome:REACT_114210
database_cross_reference: Reactome:REACT_114331
database_cross_reference: Reactome:REACT_114379
database_cross_reference: Reactome:REACT_114384
database_cross_reference: Reactome:REACT_114532
database_cross_reference: Reactome:REACT_114620
database_cross_reference: Reactome:REACT_114824
database_cross_reference: Reactome:REACT_115229
database_cross_reference: Reactome:REACT_115324
database_cross_reference: Reactome:REACT_12396
database_cross_reference: Reactome:REACT_12397
database_cross_reference: Reactome:REACT_12456
database_cross_reference: Reactome:REACT_12612
database_cross_reference: Reactome:REACT_15316
database_cross_reference: Reactome:REACT_15335
database_cross_reference: Reactome:REACT_15449
database_cross_reference: Reactome:REACT_15495
database_cross_reference: Reactome:REACT_19123
database_cross_reference: Reactome:REACT_19178

Adenylate cyclase increases the GTPase activity of G alpha-olf, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102208

Adenylate cyclase increases the GTPase activity of Gi alpha, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102307

Vesicle Uncoating, Oryza sativa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102371

trans-Golgi Network Vesicle Scission, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102510

Loss of Sar1b GTPase, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102532

trans-Golgi Network Lysosomal Vesicle Scission, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103518

G alpha (i) auto-inactivates by hydrolysing GTP to GDP, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104081

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104477

Loss of Sar1b GTPase, Dictyostelium discoideum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104739

trans-Golgi Network Vesicle Scission, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105323

G-protein alpha subunit is inactivated, Saccharomyces cerevisiae
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105697

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105708

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105854

Vesicle Uncoating, Saccharomyces cerevisiae
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106121

Hydrolysis of eEF1A:GTP, Dictyostelium discoideum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106217

Adenylate cyclase increases the GTPase activity of G alpha-olf, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106301

trans-Golgi Network Lysosomal Vesicle Scission, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106528

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107176

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107306

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Saccharomyces cerevisiae
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107730

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107820

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108363

G-protein alpha subunit is inactivated, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108653

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108825

trans-Golgi Network Vesicle Scission, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108837

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109360

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109897

G alpha (i) auto-inactivates by hydrolysing GTP to GDP, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110131

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110443

trans-Golgi Network Vesicle Scission, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110557

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Caenorhabditis elegans
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110859

G-protein alpha subunit is inactivated, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110879

G-protein alpha subunit is inactivated, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110931

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_111994

Endocytosis (internalization) of clathrin-coated vesicle, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112104

Endocytosis (internalization) of clathrin-coated vesicle, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112254

Disassembly of COPII coated vesicle, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112389

trans-Golgi Network Vesicle Scission, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112587

Vesicle Uncoating, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112651

Vesicle Uncoating, Plasmodium falciparum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112671

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Saccharomyces cerevisiae
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113058

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113209

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Saccharomyces cerevisiae
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113727

Formation of clathrin coated vesicle, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113832

Formation of clathrin coated vesicle, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113952

Endocytosis (internalization) of clathrin-coated vesicle, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113954

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114148

Loss of Sar1b GTPase, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114153

Formation of clathrin coated vesicle, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114188

G-protein alpha subunit is inactivated, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114210

trans-Golgi Network Vesicle Scission, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114331

Formation of clathrin coated vesicle, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114379

Hydrolysis of eEF1A:GTP, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114384

Formation of clathrin coated vesicle, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114532

Endocytosis (internalization) of clathrin-coated vesicle, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114620

trans-Golgi Network Lysosomal Vesicle Scission, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114824

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115229

Endocytosis (internalization) of clathrin-coated vesicle, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115324

Loss of Sar1b GTPase, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_12396

Endocytosis (internalization) of clathrin-coated vesicle, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_12397

Vesicle Uncoating, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_12456

Endocytosis of clathrin-coated vesicle, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_12612

G-protein alpha subunit is inactivated, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15316

Adenylate cyclase increases the GTPase activity of G alpha-olf, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15335

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15449

Adenylate cyclase increases the GTPase activity of Gi alpha, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15495

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19123

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19178

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19186

trans-Golgi Network Lysosomal Vesicle Scission, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19194

G alpha (i) auto-inactivates by hydrolysing GTP to GDP, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19219

trans-Golgi Network Vesicle Scission, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19255

G alpha (i)1 auto-inactivates by hydrolysing GTP to GDP, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19317

Formation of clathrin coated vesicle, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_22359

Vesicle Uncoating, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28065

Hydrolysis of eEF1A:GTP, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28251

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28269

trans-Golgi Network Lysosomal Vesicle Scission, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29162

Hydrolysis of eEF1A:GTP, Plasmodium falciparum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30456

Adenylate cyclase increases the GTPase activity of G alpha-olf, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30463

Endocytosis (internalization) of clathrin-coated vesicle, Caenorhabditis elegans
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30562

G-protein alpha subunit is inactivated, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30687

trans-Golgi Network Vesicle Scission, Caenorhabditis elegans
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30707

Vesicle Uncoating, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30942

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31226

Formation of clathrin coated vesicle, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31474

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Caenorhabditis elegans
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31530

trans-Golgi Network Lysosomal Vesicle Scission, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31599

Hydrolysis of eEF1A:GTP, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31709

Adenylate cyclase increases the GTPase activity of G alpha-olf, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31727

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31850

Loss of Sar1b GTPase, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32006

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32028

Vesicle Uncoating, Dictyostelium discoideum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32914

trans-Golgi Network Lysosomal Vesicle Scission, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33948

Vesicle Uncoating, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34113

G-protein alpha subunit is inactivated, Caenorhabditis elegans
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34480

G alpha (i) auto-inactivates by hydrolysing GTP to GDP, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34592

Adenylate cyclase increases the GTPase activity of Gi alpha, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34735

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_348

trans-Golgi Network Lysosomal Vesicle Scission, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_36834

G alpha (i) auto-inactivates by hydrolysing GTP to GDP, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_37542

Hydrolysis of eEF1A:GTP, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_552

Hydrolysis of Ran:GTP to Ran:GDP, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6171

Hydrolysis of reEF1A:GTP, Oryctolagus cuniculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_712

Disassembly of COPII coated vesicle, Homo sapiens
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_75799

Hydrolysis of eEF1A:GTP, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77032

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77303

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Caenorhabditis elegans
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78069

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78231

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78653

G-protein alpha subunit is inactivated, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78945

G alpha (i) auto-inactivates by hydrolysing GTP to GDP, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79558

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79620

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80275

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80612

Loss of Sar1b GTPase, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81304

Endocytosis (internalization) of clathrin-coated vesicle, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81448

Disassembly of COPII coated vesicle, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81580

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Caenorhabditis elegans
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81664

Vesicle Uncoating, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81879

Formation of clathrin coated vesicle, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82203

G-protein alpha subunit is inactivated, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82263

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82457

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82603

Loss of Sar1b GTPase, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82704

Adenylate cyclase increases the GTPase activity of G alpha-olf, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83308

G-protein alpha subunit is inactivated, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83403

Hydrolysis of eEF1A:GTP, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83440

Loss of Sar1b GTPase, Plasmodium falciparum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83730

Endocytosis (internalization) of clathrin-coated vesicle, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84204

Vesicle Uncoating, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84553

G-protein alpha subunit is inactivated, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84696

Hydrolysis of eEF1A:GTP, Saccharomyces cerevisiae
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84712

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84735

Vesicle Uncoating, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85008

Loss of Sar1b GTPase, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85418

Disassembly of COPII coated vesicle, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85769

Adenylate cyclase increases the GTPase activity of G alpha-olf, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85972

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Dictyostelium discoideum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86227

trans-Golgi Network Lysosomal Vesicle Scission, Caenorhabditis elegans
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86358

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Dictyostelium discoideum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86400

Vesicle Uncoating, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86630

Adenylate cyclase increases the GTPase activity of G alpha-olf, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86760

Loss of Sar1b GTPase, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86972

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Dictyostelium discoideum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87409

Formation of clathrin coated vesicle, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87506

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87558

Endocytosis (internalization) of clathrin-coated vesicle, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87653

Formation of clathrin coated vesicle, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87661

Vesicle Uncoating, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88045

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88357

Loss of Sar1b GTPase, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89231

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89292

G alpha (i) auto-inactivates by hydrolysing GTP to GDP, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89416

trans-Golgi Network Lysosomal Vesicle Scission, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89668

Vesicle Uncoating, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89763

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90050

Hydrolysis of eEF1A:GTP, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90064

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90517

G-protein alpha subunit is inactivated, Dictyostelium discoideum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90703

Adenylate cyclase increases the GTPase activity of Gi alpha, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91199

trans-Golgi Network Vesicle Scission, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91588

Endocytosis (internalization) of clathrin-coated vesicle, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92176

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92197

Loss of Sar1b GTPase, Oryza sativa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92198

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92450

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Dictyostelium discoideum
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93249

Loss of Sar1b GTPase, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93305

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93641

G-protein alpha subunit is inactivated, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93742

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93772

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94019

trans-Golgi Network Vesicle Scission, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94095

Adenylate cyclase increases the GTPase activity of Gi alpha, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94305

Adenylate cyclase increases the GTPase activity of Gi alpha, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94760

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95238

Adenylate cyclase increases the GTPase activity of Gi alpha, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95563

Loss of Sar1b GTPase, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96019

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96132

G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96223

Adenylate cyclase increases the GTPase activity of Gi alpha, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96612

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96881

Loss of Sar1b GTPase, Saccharomyces cerevisiae
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97284

Adenylaye cyclase increases the GTPase activity of G alpha-olf, Taeniopygia guttata
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97405

G alpha (i) auto-inactivates by hydrolysing GTP to GDP, Danio rerio
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97595

Loss of Sar1b GTPase, Schizosaccharomyces pombe
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97794

Formation of clathrin coated vesicle, Caenorhabditis elegans
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98431

Vesicle Uncoating, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98556

G alpha (i) auto-inactivates by hydrolysing GTP to GDP, Canis familiaris
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98837

Adenylate cyclase increases the GTPase activity of Gi alpha, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98859

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99479

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Sus scrofa
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99533

Formation of clathrin coated vesicle, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99616

Axiom
annotated source: GTPase activity
annotated property: definition
annotated target: Catalysis of the reaction: GTP + H2O = GDP + phosphate.
database_cross_reference: ISBN:0198547684

trans-Golgi Network Vesicle Scission, Mus musculus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100432

G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Bos taurus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100708

trans-Golgi Network Vesicle Scission, Rattus norvegicus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101121

G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Drosophila melanogaster
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101520

Loss of Sar1b GTPase, Arabidopsis thaliana
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101563

G-protein alpha subunit is inactivated, Gallus gallus
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101678

Adenylate cyclase increases the GTPase activity of G alpha-olf, Xenopus tropicalis
type: Axiom
annotated source: GTPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102040

helicase activity
type: Class
subclass of: hydrolase activity
definition: Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix.
database_cross_reference: Reactome:REACT_101111
database_cross_reference: Reactome:REACT_101247
database_cross_reference: Reactome:REACT_101622
database_cross_reference: Reactome:REACT_101644
database_cross_reference: Reactome:REACT_101823
database_cross_reference: Reactome:REACT_101994
database_cross_reference: Reactome:REACT_102121
database_cross_reference: Reactome:REACT_102441
database_cross_reference: Reactome:REACT_102560
database_cross_reference: Reactome:REACT_1033
database_cross_reference: Reactome:REACT_103861
database_cross_reference: Reactome:REACT_103881
database_cross_reference: Reactome:REACT_103897
database_cross_reference: Reactome:REACT_103959
database_cross_reference: Reactome:REACT_104221
database_cross_reference: Reactome:REACT_105950
database_cross_reference: Reactome:REACT_106346
database_cross_reference: Reactome:REACT_107072
database_cross_reference: Reactome:REACT_107495
database_cross_reference: Reactome:REACT_108159
database_cross_reference: Reactome:REACT_108648
database_cross_reference: Reactome:REACT_108654
database_cross_reference: Reactome:REACT_109035
database_cross_reference: Reactome:REACT_109161
database_cross_reference: Reactome:REACT_110588
database_cross_reference: Reactome:REACT_110827
database_cross_reference: Reactome:REACT_110845
database_cross_reference: Reactome:REACT_112208
database_cross_reference: Reactome:REACT_112817
database_cross_reference: Reactome:REACT_113177
database_cross_reference: Reactome:REACT_1521
database_cross_reference: Reactome:REACT_1817
database_cross_reference: Reactome:REACT_1844
database_cross_reference: Reactome:REACT_28131
database_cross_reference: Reactome:REACT_28343
database_cross_reference: Reactome:REACT_28810
database_cross_reference: Reactome:REACT_28880
database_cross_reference: Reactome:REACT_29155
database_cross_reference: Reactome:REACT_29217
database_cross_reference: Reactome:REACT_29818
database_cross_reference: Reactome:REACT_29850
database_cross_reference: Reactome:REACT_30013
database_cross_reference: Reactome:REACT_30989
database_cross_reference: Reactome:REACT_31034
database_cross_reference: Reactome:REACT_31090
database_cross_reference: Reactome:REACT_31554
database_cross_reference: Reactome:REACT_32533
database_cross_reference: Reactome:REACT_33205
database_cross_reference: Reactome:REACT_34016
database_cross_reference: Reactome:REACT_34089
database_cross_reference: Reactome:REACT_34560
database_cross_reference: Reactome:REACT_40
database_cross_reference: Reactome:REACT_6134
database_cross_reference: Reactome:REACT_6184
database_cross_reference: Reactome:REACT_6325
database_cross_reference: Reactome:REACT_6758
database_cross_reference: Reactome:REACT_6768
database_cross_reference: Reactome:REACT_6853
database_cross_reference: Reactome:REACT_6922
database_cross_reference: Reactome:REACT_78086
database_cross_reference: Reactome:REACT_78462
database_cross_reference: Reactome:REACT_78667
database_cross_reference: Reactome:REACT_78771
database_cross_reference: Reactome:REACT_79759
database_cross_reference: Reactome:REACT_80107
database_cross_reference: Reactome:REACT_80325
database_cross_reference: Reactome:REACT_80500
database_cross_reference: Reactome:REACT_80532
database_cross_reference: Reactome:REACT_80605
database_cross_reference: Reactome:REACT_81126
database_cross_reference: Reactome:REACT_81335
database_cross_reference: Reactome:REACT_81427
database_cross_reference: Reactome:REACT_81441
database_cross_reference: Reactome:REACT_81682
database_cross_reference: Reactome:REACT_82776
database_cross_reference: Reactome:REACT_83794
database_cross_reference: Reactome:REACT_84565

Axiom
annotated source: helicase activity
annotated property: definition
annotated target: Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix.
database_cross_reference: GOC:mah
database_cross_reference: ISBN:0198506732

Addition of the third nucleotide on the nascent transcript, Saccharomyces cerevisiae
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101111

Formation of open bubble structure in DNA by helicases, Bos taurus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101247

MCM8 mediated fork unwinding, Danio rerio
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101622

Formation of open bubble structure in DNA by helicases, Oryza sativa
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101644

MCM2-7 mediated fork unwinding, Plasmodium falciparum
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101823

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Xenopus tropicalis
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101994

Addition of the third nucleotide on the nascent transcript, Rattus norvegicus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102121

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Gallus gallus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102441

MCM2-7 mediated fork unwinding, Oryza sativa
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102560

Formation of open bubble structure in DNA by helicases, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1033

MCM8 mediated fork unwinding, Bos taurus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103861

RNA Polymerase II Promoter Opening: First Transition, Dictyostelium discoideum
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103881

MCM8 mediated fork unwinding, Mus musculus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103897

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Rattus norvegicus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103959

MCM2-7 mediated fork unwinding, Rattus norvegicus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104221

MCM2-7 mediated fork unwinding, Xenopus tropicalis
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105950

Formation of open bubble structure in DNA by helicases, Taeniopygia guttata
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106346

Formation of open bubble structure in DNA by helicases, Mus musculus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107072

RNA Polymerase II Promoter Opening: First Transition, Taeniopygia guttata
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107495

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Dictyostelium discoideum
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108159

Addition of the third nucleotide on the nascent transcript, Arabidopsis thaliana
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108648

MCM2-7 mediated fork unwinding, Schizosaccharomyces pombe
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108654

RNA Polymerase II Promoter Opening: First Transition, Schizosaccharomyces pombe
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109035

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Arabidopsis thaliana
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109161

MCM8 mediated fork unwinding, Xenopus tropicalis
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110588

Formation of open bubble structure in DNA by helicases, Danio rerio
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110827

Cap-bound mRNA is activated by helicases, Mus musculus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110845

MCM8 mediated fork unwinding, Drosophila melanogaster
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112208

Cap-bound mRNA is activated by helicases, Schizosaccharomyces pombe
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112817

Formation of open bubble structure in DNA by helicases, Caenorhabditis elegans
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113177

Cap-bound mRNA is activated by helicases, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1521

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1817

RNA Polymerase II Promoter Opening: First Transition, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1844

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Drosophila melanogaster
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28131

MCM2-7 mediated fork unwinding, Danio rerio
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28343

Addition of the third nucleotide on the nascent transcript, Oryza sativa
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28810

MCM2-7 mediated fork unwinding, Drosophila melanogaster
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28880

Addition of the third nucleotide on the nascent transcript, Drosophila melanogaster
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29155

Formation of open bubble structure in DNA by helicases, Xenopus tropicalis
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29217

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Oryza sativa
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29818

RNA Polymerase II Promoter Opening: First Transition, Saccharomyces cerevisiae
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29850

MCM8 mediated fork unwinding, Rattus norvegicus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30013

MCM8 mediated fork unwinding, Arabidopsis thaliana
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30989

Cap-bound mRNA is activated by helicases, Danio rerio
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31034

MCM2-7 mediated fork unwinding, Gallus gallus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31090

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Schizosaccharomyces pombe
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31554

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Caenorhabditis elegans
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32533

MCM8 mediated fork unwinding, Canis familiaris
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33205

Formation of open bubble structure in DNA by helicases, Rattus norvegicus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34016

MCM2-7 mediated fork unwinding, Dictyostelium discoideum
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34089

MCM8 mediated fork unwinding, Sus scrofa
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34560

Addition of the third nucleotide on the nascent transcript, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_40

HIV-1 Promoter Opening: First Transition, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6134

Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6184

Addition of the third nucleotide on the nascent HIV-1 transcript, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6325

Xenopus Mcm8 mediated fork unwinding, Xenopus laevis
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6758

MCM8 mediated fork unwinding, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6768

Yeast Mcm2-7 mediated fork unwinding, Saccharomyces cerevisiae
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6853

MCM2-7 mediated fork unwinding, Homo sapiens
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6922

RNA Polymerase II Promoter Opening: First Transition, Rattus norvegicus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78086

Formation of open bubble structure in DNA by helicases, Drosophila melanogaster
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78462

MCM2-7 mediated fork unwinding, Canis familiaris
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78667

MCM8 mediated fork unwinding, Dictyostelium discoideum
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78771

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Mus musculus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79759

RNA Polymerase II Promoter Opening: First Transition, Arabidopsis thaliana
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80107

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Danio rerio
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80325

MCM8 mediated fork unwinding, Gallus gallus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80500

Addition of the third nucleotide on the nascent transcript, Gallus gallus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80532

Addition of the third nucleotide on the nascent transcript, Mus musculus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80605

Addition of the third nucleotide on the nascent transcript, Schizosaccharomyces pombe
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81126

RNA Polymerase II Promoter Opening: First Transition, Gallus gallus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81335

MCM8 mediated fork unwinding, Taeniopygia guttata
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81427

MCM8 mediated fork unwinding, Oryza sativa
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81441

Formation of open bubble structure in DNA by helicases, Canis familiaris
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81682

RNA Polymerase II Promoter Opening: First Transition, Danio rerio
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82776

Formation of open bubble structure in DNA by helicases, Gallus gallus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83794

Formation of open bubble structure in DNA by helicases, Schizosaccharomyces pombe
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84565

Cap-bound mRNA is activated by helicases, Canis familiaris
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84574

MCM2-7 mediated fork unwinding, Mus musculus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84809

MCM2-7 mediated fork unwinding, Taeniopygia guttata
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84907

Cap-bound mRNA is activated by helicases, Drosophila melanogaster
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85111

MCM2-7 mediated fork unwinding, Arabidopsis thaliana
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85172

MCM2-7 mediated fork unwinding, Caenorhabditis elegans
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86220

Addition of the third nucleotide on the nascent transcript, Caenorhabditis elegans
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88362

MCM2-7 mediated fork unwinding, Bos taurus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89000

Formation of open bubble structure in DNA by helicases, Saccharomyces cerevisiae
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89030

Addition of the third nucleotide on the nascent transcript, Xenopus tropicalis
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89363

RNA Polymerase II Promoter Opening: First Transition, Drosophila melanogaster
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89694

MCM8 mediated fork unwinding, Plasmodium falciparum
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91822

RNA Polymerase II Promoter Opening: First Transition, Oryza sativa
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93391

RNA Polymerase II Promoter Opening: First Transition, Mus musculus
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93711

RNA Polymerase II Promoter Opening: First Transition, Xenopus tropicalis
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94645

RNA Polymerase II Promoter Opening: First Transition, Caenorhabditis elegans
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94679

Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Saccharomyces cerevisiae
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95942

Formation of open bubble structure in DNA by helicases, Arabidopsis thaliana
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95993

Addition of the third nucleotide on the nascent transcript, Dictyostelium discoideum
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98273

Formation of open bubble structure in DNA by helicases, Sus scrofa
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98302

Cap-bound mRNA is activated by helicases, Xenopus tropicalis
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98745

Addition of the third nucleotide on the nascent transcript, Danio rerio
type: Axiom
annotated source: helicase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99120

nuclease activity
type: Class
subclass of: hydrolase activity
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Catalysis of the hydrolysis of ester linkages within nucleic acids.
database_cross_reference: EC:3.1.-.-
has_obo_namespace: molecular_function
id: GO:0004518
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.

Axiom
annotated source: nuclease activity
annotated property: definition
annotated target: Catalysis of the hydrolysis of ester linkages within nucleic acids.
database_cross_reference: ISBN:0198547684

signal transducer activity
type: Class
subclass of: molecular_function
subclass of: Restriction
  on property: part of
  some values from: signaling
definition: Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
has_alternative_id: GO:0005062
has_alternative_id: GO:0009369
has_alternative_id: GO:0009370
has_narrow_synonym: hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity
has_narrow_synonym: quorum sensing response regulator activity
has_narrow_synonym: quorum sensing signal generator activity
has_obo_namespace: molecular_function
id: GO:0004871
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok
comment: Ligands do NOT have the molecular function 'signal transducer activity'.

Axiom
annotated source: signal transducer activity
annotated property: definition
annotated target: Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
database_cross_reference: GOC:go_curators

guanyl-nucleotide exchange factor activity
type: Class
subclass of: molecular_function
definition: Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
has_alternative_id: GO:0008433
has_alternative_id: GO:0016219
has_alternative_id: GO:0019839
database_cross_reference: Reactome:REACT_100054
database_cross_reference: Reactome:REACT_100149
database_cross_reference: Reactome:REACT_100160
database_cross_reference: Reactome:REACT_100220
database_cross_reference: Reactome:REACT_100376
database_cross_reference: Reactome:REACT_100844
database_cross_reference: Reactome:REACT_100845
database_cross_reference: Reactome:REACT_100865
database_cross_reference: Reactome:REACT_101114
database_cross_reference: Reactome:REACT_101120
database_cross_reference: Reactome:REACT_101134
database_cross_reference: Reactome:REACT_101148
database_cross_reference: Reactome:REACT_101201
database_cross_reference: Reactome:REACT_101347
database_cross_reference: Reactome:REACT_101383
database_cross_reference: Reactome:REACT_101464
database_cross_reference: Reactome:REACT_101601
database_cross_reference: Reactome:REACT_102077
database_cross_reference: Reactome:REACT_102765
database_cross_reference: Reactome:REACT_103302
database_cross_reference: Reactome:REACT_103339
database_cross_reference: Reactome:REACT_103405
database_cross_reference: Reactome:REACT_103624
database_cross_reference: Reactome:REACT_103967
database_cross_reference: Reactome:REACT_104045
database_cross_reference: Reactome:REACT_104400
database_cross_reference: Reactome:REACT_104431
database_cross_reference: Reactome:REACT_104640
database_cross_reference: Reactome:REACT_104773
database_cross_reference: Reactome:REACT_105341
database_cross_reference: Reactome:REACT_105372
database_cross_reference: Reactome:REACT_105430
database_cross_reference: Reactome:REACT_105942
database_cross_reference: Reactome:REACT_106103
database_cross_reference: Reactome:REACT_106278
database_cross_reference: Reactome:REACT_106432
database_cross_reference: Reactome:REACT_106521
database_cross_reference: Reactome:REACT_106839
database_cross_reference: Reactome:REACT_106962
database_cross_reference: Reactome:REACT_107078
database_cross_reference: Reactome:REACT_107457
database_cross_reference: Reactome:REACT_108239
database_cross_reference: Reactome:REACT_108491
database_cross_reference: Reactome:REACT_108921
database_cross_reference: Reactome:REACT_109910
database_cross_reference: Reactome:REACT_109998
database_cross_reference: Reactome:REACT_110266
database_cross_reference: Reactome:REACT_110292
database_cross_reference: Reactome:REACT_110300
database_cross_reference: Reactome:REACT_110415
database_cross_reference: Reactome:REACT_110820
database_cross_reference: Reactome:REACT_110821
database_cross_reference: Reactome:REACT_111195
database_cross_reference: Reactome:REACT_112168
database_cross_reference: Reactome:REACT_112243
database_cross_reference: Reactome:REACT_112276
database_cross_reference: Reactome:REACT_112354
database_cross_reference: Reactome:REACT_113007
database_cross_reference: Reactome:REACT_113090
database_cross_reference: Reactome:REACT_113408
database_cross_reference: Reactome:REACT_113526
database_cross_reference: Reactome:REACT_113541
database_cross_reference: Reactome:REACT_113598
database_cross_reference: Reactome:REACT_114659
database_cross_reference: Reactome:REACT_114904
database_cross_reference: Reactome:REACT_115094
database_cross_reference: Reactome:REACT_115111
database_cross_reference: Reactome:REACT_115210
database_cross_reference: Reactome:REACT_115748
database_cross_reference: Reactome:REACT_12037
database_cross_reference: Reactome:REACT_12071
database_cross_reference: Reactome:REACT_12083
database_cross_reference: Reactome:REACT_1214
database_cross_reference: Reactome:REACT_12453

Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: definition
annotated target: Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
database_cross_reference: GOC:kd
database_cross_reference: GOC:mah

Liganded Gs-activating GPCR acts as a GEF for Gs, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100054

(Frs2)C3G stimulates nucleotide exchange on Rap1, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100149

Liganded Gi-activating GPCR acts as a GEF for Gi, Dictyostelium discoideum
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100160

Liganded Gs-activating GPCR acts as a GEF for Gs, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100220

C3G stimulates nucleotide exchange on Rap1, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100376

Activation of Cdc42 by pVav1, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100844

Gi activation by P2Y purinoceptor 12, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100845

Gq activation by P2Y purinoceptor 1, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100865

Activation of Rap1 by membrane-associated GEFs, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101114

Liganded Gi-activating GPCR acts as a GEF for Gi, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101120

Opsins that act as GEFs for G alpha-t, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101134

Activation of Rap1 by membrane-associated GEFs, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101148

(Frs2)C3G stimulates nucleotide exchange on Rap1, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101201

Liganded Gz-activating GPCR acts as a GEF for Gz, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101347

Gs activation by prostacyclin receptor, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101383

Activation of Rap1 by membrane-associated GEFs, Caenorhabditis elegans
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101464

Activation of Rac1 by pVav1, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101601

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102077

Activation of Rac1 by pVav1, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102765

Sar1p Activation And Membrane Binding, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103302

Liganded Gi-activating GPCR acts as a GEF for Gi, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103339

Activation of Cdc42 by pVav1, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103405

C3G stimulates nucleotide exchange on Rap1, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103624

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103967

Liganded Gz-activating GPCR acts as a GEF for Gz, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104045

p115-RhoGEF activation of Rac1, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104400

G13 activation by TP receptor, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104431

G13 activation by TP receptor, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104640

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104773

VAV2 is a GEF for Rho/Rac family kinases, Caenorhabditis elegans
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105341

Gq activation by P2Y purinoceptor 1, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105372

Gq activation by P2Y purinoceptor 1, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105430

Opsins that act as GEFs for G alpha-t, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105942

Liganded Gi-activating GPCR acts as a GEF for Gi, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106103

Activation of Rap1 by cytosolic GEFs, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106278

Liganded Gi-activating GPCR acts as a GEF for Gi, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106432

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106521

Activation of Rac1 by pVav1, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106839

Gq activation by TP receptor, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106962

Activation of Rac1 by pVav1, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107078

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107457

Opsins that act as GEFs for G alpha-t, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108239

VAV2 is a GEF for Rho/Rac family kinases, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108491

Activation of Gq by Fatty Acid Receptor 1: Fatty Acid Complex, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108921

Liganded Gz-activating GPCR acts as a GEF for Gz, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109910

Gi activation by P2Y purinoceptor 12, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109998

Liganded Gs-activating GPCR acts as a GEF for Gs, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110266

Gs activation by prostacyclin receptor, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110292

Sar1p Activation And Membrane Binding, Oryza sativa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110300

(Frs2)C3G stimulates nucleotide exchange on Rap1, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110415

C3G stimulates nucleotide exchange on Rap1, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110820

VAV3 is a GEF for Rho/Rac family kinases, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110821

Activation of RAC1, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_111195

Activation of Gq by Muscarinic Acetylcholine Receptor M3, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112168

Activation of RAC1, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112243

VAV2 is a GEF for Rho/Rac family kinases, Schizosaccharomyces pombe
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112276

Activation of RAC1, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112354

Activation of RAC1, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113007

p115-RhoGEF activation of Rac1, Caenorhabditis elegans
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113090

VAV2 is a GEF for Rho/Rac family kinases, Saccharomyces cerevisiae
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113408

Activation of Rap1 by membrane-associated GEFs, Drosophila melanogaster
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113526

p115-RhoGEF activation of Rac1, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113541

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Dictyostelium discoideum
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113598

Activation of Gq by Fatty Acid Receptor 1: Fatty Acid Complex, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114659

VAV3 is a GEF for Rho/Rac family kinases, Saccharomyces cerevisiae
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114904

VAV1 is a GEF for Rho/Rac family kinases, Caenorhabditis elegans
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115094

VAV3 is a GEF for Rho/Rac family kinases, Schizosaccharomyces pombe
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115111

Activation of RAC1, Drosophila melanogaster
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115210

Rit is activated, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115748

C3G stimulates nucleotide exchange on Rap1, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_12037

RIT/RIN are activated, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_12071

(Frs2)C3G stimulates nucleotide exchange on Rap1, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_12083

p115-RhoGEF activation of Rac1, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1214

C3G stimulates nucleotide exchange on Rap1, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_12453

Sar1p Activation And Membrane Binding, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_12554

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_13694

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15291

Activation of Rap1 by cytosolic GEFs, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15507

Liganded Gi-activating GPCR acts as a GEF for Gi, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15538

Liganded Gs-activating GPCR acts as a GEF for Gs, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_17008

Activation of Gq by Muscarinic Acetylcholine Receptor M3, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_18309

Opsins that act as GEFs for G alpha-t, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_18400

Activation of Rac1 by pVav1, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19243

Activation of Cdc42 by pVav1, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19286

Activation of Gq by Fatty Acid Receptor 1: Fatty Acid Complex, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19346

Gi activation by P2Y purinoceptor 12, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20507

Gq activation by TP receptor, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20511

G13 activation by TP receptor, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20567

Gq activation by P2Y purinoceptor 1, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20636

Glucagon:GCGR mediates GTP-GDP exchange, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_22110

Activation of Gq by Muscarinic Acetylcholine Receptor M3 (mouse), Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_22134

Activation of Rac1 by VAV2, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_22180

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_22370

Liganded Gz-activating GPCR acts as a GEF for Gz, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_22380

VAV2 is a GEF for Rho/Rac family kinases, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_23806

Gs activation by prostacyclin receptor, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_23823

Activation of Rap1 by membrane-associated GEFs, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_23833

VAV3 is a GEF for Rho/Rac family kinases, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_23936

VAV1 is a GEF for Rho/Rac family kinases, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_24016

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28676

VAV2 is a GEF for Rho/Rac family kinases, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29276

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29380

Regeneration of eEF1A:GTP by eEF1B activity, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29556

Liganded Gs-activating GPCR acts as a GEF for Gs, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29675

Liganded Gi-activating GPCR acts as a GEF for Gi, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30010

Gq activation by TP receptor, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30405

VAV1 is a GEF for Rho/Rac family kinases, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30438

Liganded Gs-activating GPCR acts as a GEF for Gs, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30603

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Drosophila melanogaster
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30730

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30735

Opsins that act as GEFs for G alpha-t, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30905

Sar1p Activation And Membrane Binding, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31044

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31228

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31456

VAV3 is a GEF for Rho/Rac family kinases, Drosophila melanogaster
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31493

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31796

Liganded Gz-activating GPCR acts as a GEF for Gz, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31909

VAV2 is a GEF for Rho/Rac family kinases, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32415

Gi activation by P2Y purinoceptor 12, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33219

Activation of Gq by Muscarinic Acetylcholine Receptor M3, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33232

Activation of Rac1 by pVav1, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33439

(Frs2)C3G stimulates nucleotide exchange on Rap1, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33449

p115-RhoGEF activation of Rac1, Drosophila melanogaster
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33674

G13 activation by TP receptor, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33737

Activation of Rap1 by cytosolic GEFs, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34008

Activation of Gq by Muscarinic Acetylcholine Receptor M3, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34487

Sar1p Activation And Membrane Binding, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_36332

Gi activation by P2Y purinoceptor 12, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_44918

GDP is exchanged for GTP on DRheb, Drosophila melanogaster
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6224

Regeneration of eEF1A:GTP by eEF1B activity, Homo sapiens
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_67

Sar1p Activation And Membrane Binding, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77041

Liganded Gz-activating GPCR acts as a GEF for Gz, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77066

G13 activation by TP receptor, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77652

Liganded Gs-activating GPCR acts as a GEF for Gs, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77906

Liganded Gi-activating GPCR acts as a GEF for Gi, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78375

Gq activation by TP receptor, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78455

Liganded Gi-activating GPCR acts as a GEF for Gi, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78720

Activation of Rap1 by cytosolic GEFs, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78874

Sar1p Activation And Membrane Binding, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78967

Activation of Cdc42 by pVav1, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79160

Gq activation by TP receptor, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79254

Activation of Rap1 by membrane-associated GEFs, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79314

Liganded Gz-activating GPCR acts as a GEF for Gz, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79499

Liganded Gz-activating GPCR acts as a GEF for Gz, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79750

VAV2 is a GEF for Rho/Rac family kinases, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79783

Gq activation by P2Y purinoceptor 1, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79862

VAV1 is a GEF for Rho/Rac family kinases, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80006

Gs activation by prostacyclin receptor, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80507

Activation of Rap1 by membrane-associated GEFs, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80641

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80694

VAV3 is a GEF for Rho/Rac family kinases, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80807

Liganded Gs-activating GPCR acts as a GEF for Gs, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81349

Gi activation by P2Y purinoceptor 12, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82067

Liganded Gi-activating GPCR acts as a GEF for Gi, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82396

Regeneration of eEF1A:GTP by eEF1B activity, Plasmodium falciparum
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82522

(Frs2)C3G stimulates nucleotide exchange on Rap1, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82999

p115-RhoGEF activation of Rac1, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83022

Gs activation by prostacyclin receptor, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83060

VAV2 is a GEF for Rho/Rac family kinases, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83264

Opsins that act as GEFs for G alpha-t, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83428

Activation of Rap1 by membrane-associated GEFs, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83544

Activation of Gq by Muscarinic Acetylcholine Receptor M3, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83699

Sar1p Activation And Membrane Binding, Arabidopsis thaliana
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84621

VAV3 is a GEF for Rho/Rac family kinases, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85103

Activation of Cdc42 by pVav1, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85579

Gq activation by TP receptor, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85654

VAV1 is a GEF for Rho/Rac family kinases, Drosophila melanogaster
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85754

Activation of Rap1 by membrane-associated GEFs, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86122

p115-RhoGEF activation of Rac1, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86161

p115-RhoGEF activation of Rac1, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86316

VAV3 is a GEF for Rho/Rac family kinases, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86337

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86600

G13 activation by TP receptor, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86605

G13 activation by TP receptor, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86755

VAV2 is a GEF for Rho/Rac family kinases, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87162

Activation of Rap1 by cytosolic GEFs, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87376

Activation of Rap1 by cytosolic GEFs, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87420

C3G stimulates nucleotide exchange on Rap1, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87432

Gq activation by TP receptor, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88322

Activation of Gq by Fatty Acid Receptor 1: Fatty Acid Complex, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88390

Liganded Gz-activating GPCR acts as a GEF for Gz, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88466

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88628

VAV3 is a GEF for Rho/Rac family kinases, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88693

Gi activation by P2Y purinoceptor 12, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88712

Gi activation by P2Y purinoceptor 12, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88844

Gi activation by P2Y purinoceptor 12, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88931

Opsins that act as GEFs for G alpha-t, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88989

Gs activation by prostacyclin receptor, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89041

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89183

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89187

(Frs2)C3G stimulates nucleotide exchange on Rap1, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89508

G13 activation by TP receptor, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89638

Activation of Rap1 by cytosolic GEFs, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89812

C3G stimulates nucleotide exchange on Rap1, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89832

Activation of Rap1 by cytosolic GEFs, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89894

Gs activation by prostacyclin receptor, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90259

VAV1 is a GEF for Rho/Rac family kinases, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90547

Activation of Gq by Fatty Acid Receptor 1: Fatty Acid Complex, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90621

Activation of Gq by Muscarinic Acetylcholine Receptor M3, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90735

Gq activation by TP receptor, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90851

G13 activation by TP receptor, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90883

Liganded Gz-activating GPCR acts as a GEF for Gz, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90952

VAV3 is a GEF for Rho/Rac family kinases, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90957

VAV3 is a GEF for Rho/Rac family kinases, Caenorhabditis elegans
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90972

Gq activation by P2Y purinoceptor 1, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91040

VAV2 is a GEF for Rho/Rac family kinases, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91047

Activation of Cdc42 by pVav1, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91400

Activation of Rap1 by cytosolic GEFs, Caenorhabditis elegans
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91460

Activation of Cdc42 by pVav1, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91485

Activation of Gq by Muscarinic Acetylcholine Receptor M3, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91527

Gq activation by TP receptor, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91561

Activation of Rac1 by pVav1, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92090

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92296

Activation of Gq by Fatty Acid Receptor 1: Fatty Acid Complex, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92362

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92743

Liganded Gi-activating GPCR acts as a GEF for Gi, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92880

Gq activation by P2Y purinoceptor 1, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93072

Sar1p Activation And Membrane Binding, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93077

Activation of Rac1 by pVav1, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93108

G13 activation by TP receptor, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93352

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93442

C3G stimulates nucleotide exchange on Rap1, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93643

Gq activation by TP receptor, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93708

(Frs2)C3G stimulates nucleotide exchange on Rap1, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93824

C3G stimulates nucleotide exchange on Rap1, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93888

p115-RhoGEF activation of Rac1, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93898

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93925

Activation of Rap1 by cytosolic GEFs, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94029

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94065

VAV3 is a GEF for Rho/Rac family kinases, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94237

Gi activation by P2Y purinoceptor 12, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94277

(Frs2)C3G stimulates nucleotide exchange on Rap1, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94454

VAV2 is a GEF for Rho/Rac family kinases, Drosophila melanogaster
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94569

Activation of Rap1 by membrane-associated GEFs, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94684

Gq activation by P2Y purinoceptor 1, Canis familiaris
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94737

VAV1 is a GEF for Rho/Rac family kinases, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94953

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95254

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95591

Activation of Gq by Muscarinic Acetylcholine Receptor M3, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96016

Activation of Cdc42 by pVav1, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96673

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96836

Liganded G12/13-activating GPCR acts as a GEF for G12/13, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96942

Activation of Rap1 by membrane-associated GEFs, Taeniopygia guttata
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97040

Activation of Rap1 by cytosolic GEFs, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97508

Regeneration of eEF1A:GTP by eEF1B activity, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97558

Liganded Gs-activating GPCR acts as a GEF for Gs, Bos taurus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97631

C3G stimulates nucleotide exchange on Rap1, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97694

Activation of Rap1 by membrane-associated GEFs, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97921

Gq activation by P2Y purinoceptor 1, Sus scrofa
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97991

VAV2 is a GEF for Rho/Rac family kinases, Mus musculus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98174

Gs activation by prostacyclin receptor, Xenopus tropicalis
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98386

Gq activation by P2Y purinoceptor 1, Gallus gallus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98453

VAV2 is a GEF for Rho/Rac family kinases, Rattus norvegicus
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98827

Sar1p Activation And Membrane Binding, Drosophila melanogaster
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99149

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Danio rerio
type: Axiom
annotated source: guanyl-nucleotide exchange factor activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99303

structural molecule activity
type: Class
subclass of: molecular_function
definition: The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell.
has_obo_namespace: molecular_function
id: GO:0005198
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: structural molecule activity
annotated property: definition
annotated target: The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell.
database_cross_reference: GOC:mah

cellular_component
type: Class
definition: The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
has_alternative_id: GO:0008372
database_cross_reference: NIF_Subcellular:sao-1337158144
database_cross_reference: NIF_Subcellular:sao1337158144
has_exact_synonym: cell or subcellular entity
has_exact_synonym: cellular component
has_obo_namespace: cellular_component
has_related_synonym: subcellular entity
id: GO:0005575
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. Note that when this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this.

Axiom
annotated source: cellular_component
annotated property: definition
annotated target: The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
database_cross_reference: GOC:go_curators
database_cross_reference: NIF_Subcellular:sao-1337158144

Axiom
annotated source: cellular_component
annotated property: has_related_synonym
annotated target: subcellular entity
database_cross_reference: NIF_Subcellular:nlx_subcell_100315

extracellular region
type: Class
subclass of: cellular_component
definition: The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
database_cross_reference: Wikipedia:Extracellular
has_exact_synonym: extracellular
has_obo_namespace: cellular_component
id: GO:0005576
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'.

Axiom
annotated source: extracellular region
annotated property: definition
annotated target: The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
database_cross_reference: GOC:go_curators

cell wall
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cellular_component
definition: The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
database_cross_reference: Wikipedia:Cell_wall
has_obo_namespace: cellular_component
id: GO:0005618
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cell wall
annotated property: definition
annotated target: The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
database_cross_reference: GOC:giardia
database_cross_reference: ISBN:0198547684
database_cross_reference: PMID:15134259
database_cross_reference: http://en.wikipedia.org/wiki/Microbial_cyst

obsolete membrane fraction
type: Class
definition: OBSOLETE: That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes.
consider: GO:0016020
has_exact_synonym: membrane fraction
has_obo_namespace: cellular_component
id: GO:0005624
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim yeast
in_subset: gosubset prok
comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.
deprecated: true

Axiom
annotated source: obsolete membrane fraction
annotated property: definition
annotated target: OBSOLETE: That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes.
database_cross_reference: GOC:ma

nucleus
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cellular_component
definition: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
database_cross_reference: NIF_Subcellular:sao1702920020
database_cross_reference: Wikipedia:Cell_nucleus
has_exact_synonym: cell nucleus
has_obo_namespace: cellular_component
id: GO:0005634
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast

Axiom
annotated source: nucleus
annotated property: definition
annotated target: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
database_cross_reference: GOC:go_curators

chromosome
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cellular_component
definition: A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
database_cross_reference: Wikipedia:Chromosome
has_narrow_synonym: interphase chromosome
has_narrow_synonym: prophase chromosome
has_obo_namespace: cellular_component
has_related_synonym: chromatid
id: GO:0005694
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok
comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.

Axiom
annotated source: chromosome
annotated property: definition
annotated target: A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
database_cross_reference: ISBN:0198547684

nucleolus
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: nucleus
definition: A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
database_cross_reference: NIF_Subcellular:sao1820400233
database_cross_reference: Wikipedia:Nucleolus
has_obo_namespace: cellular_component
id: GO:0005730
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast

Axiom
annotated source: nucleolus
annotated property: definition
annotated target: A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
database_cross_reference: ISBN:0198506732

cytoplasm
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cellular_component
definition: All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
database_cross_reference: Wikipedia:Cytoplasm
has_obo_namespace: cellular_component
id: GO:0005737
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cytoplasm
annotated property: definition
annotated target: All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
database_cross_reference: ISBN:0198547684

mitochondrion
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cytoplasm
definition: A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
database_cross_reference: NIF_Subcellular:sao1860313010
database_cross_reference: Wikipedia:Mitochondrion
has_exact_synonym: mitochondria
has_obo_namespace: cellular_component
id: GO:0005739
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
comment: Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.)

Axiom
annotated source: mitochondrion
annotated property: definition
annotated target: A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
database_cross_reference: GOC:giardia
database_cross_reference: ISBN:0198506732

mitochondrial envelope
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: mitochondrion
definition: The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
has_obo_namespace: cellular_component
id: GO:0005740
in_subset: goslim candida
in_subset: goslim yeast

Axiom
annotated source: mitochondrial envelope
annotated property: definition
annotated target: The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
database_cross_reference: GOC:ai
database_cross_reference: GOC:pz

vacuole
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cytoplasm
definition: A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
database_cross_reference: Wikipedia:Vacuole
has_obo_namespace: cellular_component
has_related_synonym: vacuolar carboxypeptidase Y
id: GO:0005773
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: vacuole
annotated property: definition
annotated target: A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
database_cross_reference: GOC:mtg_sensu
database_cross_reference: ISBN:0198506732

peroxisome
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cytoplasm
definition: A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
has_alternative_id: GO:0019818
has_broad_synonym: peroxisome vesicle
database_cross_reference: NIF_Subcellular:sao499555322
database_cross_reference: Wikipedia:Peroxisome
has_obo_namespace: cellular_component
has_related_synonym: peroxisomal
id: GO:0005777
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim plant
in_subset: goslim yeast

Axiom
annotated source: peroxisome
annotated property: definition
annotated target: A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
database_cross_reference: GOC:pm
database_cross_reference: PMID:9302272
database_cross_reference: UniProtKB-KW:KW-0576

Axiom
annotated source: peroxisome
annotated property: has_related_synonym
annotated target: peroxisomal
database_cross_reference: GOC:curators

endoplasmic reticulum
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cytoplasm
subclass of: Restriction
  on property: part of
  some values from: endomembrane system
definition: The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
database_cross_reference: NIF_Subcellular:sao1036339110
database_cross_reference: Wikipedia:Endoplasmic_reticulum
has_exact_synonym: ER
has_obo_namespace: cellular_component
id: GO:0005783
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast

Axiom
annotated source: endoplasmic reticulum
annotated property: definition
annotated target: The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
database_cross_reference: ISBN:0198506732

Golgi apparatus
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: endomembrane system
definition: A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
has_broad_synonym: Golgi
database_cross_reference: NIF_Subcellular:sao451912436
database_cross_reference: Wikipedia:Golgi_apparatus
has_exact_synonym: Golgi complex
has_narrow_synonym: Golgi ribbon
has_obo_namespace: cellular_component
id: GO:0005794
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
comment: Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.

Axiom
annotated source: Golgi apparatus
annotated property: definition
annotated target: A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
database_cross_reference: ISBN:0198506732

microtubule organizing center
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cytoskeleton
definition: An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
database_cross_reference: Wikipedia:Microtubule_organizing_center
has_exact_synonym: MTOC
has_exact_synonym: microtubule organising centre
has_obo_namespace: cellular_component
id: GO:0005815
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast

Axiom
annotated source: microtubule organizing center
annotated property: definition
annotated target: An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
database_cross_reference: GOC:vw
database_cross_reference: ISBN:0815316194
database_cross_reference: PMID:17072892
database_cross_reference: PMID:17245416
database_cross_reference: http://en.wikipedia.org/wiki/Microtubule_organizing_center

ribosome
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cytoplasm
definition: An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
has_alternative_id: GO:0033279
database_cross_reference: NIF_Subcellular:sao1429207766
database_cross_reference: Wikipedia:Ribosome
has_narrow_synonym: free ribosome
has_narrow_synonym: membrane bound ribosome
has_obo_namespace: cellular_component
has_related_synonym: ribosomal RNA
id: GO:0005840
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: ribosome
annotated property: definition
annotated target: An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
database_cross_reference: ISBN:0198506732

Axiom
annotated source: ribosome
annotated property: has_narrow_synonym
annotated target: free ribosome
database_cross_reference: NIF_Subcellular:sao1139385046

Axiom
annotated source: ribosome
annotated property: has_narrow_synonym
annotated target: membrane bound ribosome
database_cross_reference: NIF_Subcellular:sao1291545653

cytoskeleton
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cellular_component
definition: Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
database_cross_reference: Wikipedia:Cytoskeleton
has_obo_namespace: cellular_component
id: GO:0005856
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cytoskeleton
annotated property: definition
annotated target: Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
database_cross_reference: GOC:mah
database_cross_reference: ISBN:0198547684
database_cross_reference: PMID:16959967

plasma membrane
type: Class
subclass of: membrane
subclass of: Restriction
  on property: part of
  some values from: cellular_component
definition: The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
has_alternative_id: GO:0005904
has_broad_synonym: juxtamembrane
database_cross_reference: NIF_Subcellular:sao1663586795
database_cross_reference: Wikipedia:Cell_membrane
has_exact_synonym: cell membrane
has_exact_synonym: cellular membrane
has_exact_synonym: cytoplasmic membrane
has_exact_synonym: plasmalemma
has_narrow_synonym: bacterial inner membrane
has_narrow_synonym: inner endospore membrane
has_narrow_synonym: plasma membrane lipid bilayer
has_obo_namespace: cellular_component
id: GO:0005886
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: plasma membrane
annotated property: definition
annotated target: The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
database_cross_reference: ISBN:0716731363

Axiom
annotated source: plasma membrane
annotated property: has_exact_synonym
annotated target: cellular membrane
database_cross_reference: NIF_Subcellular:sao6433132645

Axiom
annotated source: plasma membrane
annotated property: has_narrow_synonym
annotated target: plasma membrane lipid bilayer
database_cross_reference: GOC:mah

cellular bud
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cellular_component
definition: A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.
has_obo_namespace: cellular_component
id: GO:0005933
in_subset: goslim candida
in_subset: goslim pir
in_subset: goslim yeast

Axiom
annotated source: cellular bud
annotated property: definition
annotated target: A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.
database_cross_reference: GOC:sgd_curators

cell cortex
type: Class
subclass of: cytoplasm
subclass of: Restriction
  on property: part of
  some values from: cytoplasm
definition: The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
database_cross_reference: Wikipedia:Cell_cortex
has_obo_namespace: cellular_component
has_related_synonym: cell periphery
has_related_synonym: peripheral cytoplasm
id: GO:0005938
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim yeast

Axiom
annotated source: cell cortex
annotated property: definition
annotated target: The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
database_cross_reference: GOC:mah
database_cross_reference: ISBN:0815316194

carbohydrate metabolic process
type: Class
subclass of: biological_process
definition: The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
database_cross_reference: Reactome:REACT_102834
database_cross_reference: Reactome:REACT_103806
database_cross_reference: Reactome:REACT_104502
database_cross_reference: Reactome:REACT_105321
database_cross_reference: Reactome:REACT_106046
database_cross_reference: Reactome:REACT_107409
database_cross_reference: Reactome:REACT_115733
database_cross_reference: Reactome:REACT_28218
database_cross_reference: Reactome:REACT_32291
database_cross_reference: Reactome:REACT_33141
database_cross_reference: Reactome:REACT_33953
database_cross_reference: Reactome:REACT_34800
database_cross_reference: Reactome:REACT_474
database_cross_reference: Reactome:REACT_77669
database_cross_reference: Reactome:REACT_81945
database_cross_reference: Reactome:REACT_83038
database_cross_reference: Reactome:REACT_83329
database_cross_reference: Reactome:REACT_88330
database_cross_reference: Reactome:REACT_88558
database_cross_reference: Reactome:REACT_90099
database_cross_reference: Reactome:REACT_96375
database_cross_reference: Reactome:REACT_98394
database_cross_reference: Wikipedia:Carbohydrate_metabolism
has_exact_synonym: carbohydrate metabolism
has_obo_namespace: biological_process
id: GO:0005975
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: carbohydrate metabolic process
annotated property: definition
annotated target: The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
database_cross_reference: GOC:mah
database_cross_reference: ISBN:0198506732

Metabolism of carbohydrates, Mus musculus
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_102834

Metabolism of carbohydrates, Mycobacterium tuberculosis
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_103806

Metabolism of carbohydrates, Gallus gallus
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_104502

Metabolism of carbohydrates, Escherichia coli
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_105321

Metabolism of carbohydrates, Drosophila melanogaster
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_106046

Metabolism of carbohydrates, Caenorhabditis elegans
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_107409

Carbohydrate metabolism, Gallus gallus
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_115733

Metabolism of carbohydrates, Xenopus tropicalis
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_28218

Metabolism of carbohydrates, Staphylococcus aureus N315
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_32291

Metabolism of carbohydrates, Taeniopygia guttata
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_33141

Metabolism of carbohydrates, Rattus norvegicus
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_33953

Metabolism of carbohydrates, Danio rerio
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_34800

Metabolism of carbohydrates, Homo sapiens
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_474

Metabolism of carbohydrates, Plasmodium falciparum
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_77669

Metabolism of carbohydrates, Schizosaccharomyces pombe
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_81945

Metabolism of carbohydrates, Arabidopsis thaliana
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_83038

Metabolism of carbohydrates, Saccharomyces cerevisiae
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_83329

Metabolism of carbohydrates, Bos taurus
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_88330

Metabolism of carbohydrates, Canis familiaris
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_88558

Metabolism of carbohydrates, Sus scrofa
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_90099

Metabolism of carbohydrates, Dictyostelium discoideum
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_96375

Metabolism of carbohydrates, Oryza sativa
type: Axiom
annotated source: carbohydrate metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_98394

generation of precursor metabolites and energy
type: Class
subclass of: biological_process
definition: The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
has_broad_synonym: energy pathways
has_obo_namespace: biological_process
has_related_synonym: intermediary metabolism
has_related_synonym: metabolic energy generation
id: GO:0006091
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: generation of precursor metabolites and energy
annotated property: definition
annotated target: The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
database_cross_reference: GOC:jl

Axiom
annotated source: generation of precursor metabolites and energy
annotated property: has_related_synonym
annotated target: intermediary metabolism
database_cross_reference: GOC:mah

DNA replication
type: Class
subclass of: biological_process
definition: The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
has_alternative_id: GO:0055133
database_cross_reference: Reactome:REACT_100559
database_cross_reference: Reactome:REACT_101280
database_cross_reference: Reactome:REACT_101497
database_cross_reference: Reactome:REACT_102679
database_cross_reference: Reactome:REACT_103614
database_cross_reference: Reactome:REACT_104547
database_cross_reference: Reactome:REACT_105292
database_cross_reference: Reactome:REACT_105467
database_cross_reference: Reactome:REACT_105835
database_cross_reference: Reactome:REACT_106018
database_cross_reference: Reactome:REACT_106104
database_cross_reference: Reactome:REACT_106382
database_cross_reference: Reactome:REACT_106434
database_cross_reference: Reactome:REACT_106732
database_cross_reference: Reactome:REACT_107075
database_cross_reference: Reactome:REACT_107423
database_cross_reference: Reactome:REACT_108461
database_cross_reference: Reactome:REACT_108634
database_cross_reference: Reactome:REACT_108739
database_cross_reference: Reactome:REACT_108768
database_cross_reference: Reactome:REACT_108929
database_cross_reference: Reactome:REACT_109137
database_cross_reference: Reactome:REACT_112472
database_cross_reference: Reactome:REACT_113703
database_cross_reference: Reactome:REACT_29423
database_cross_reference: Reactome:REACT_29444
database_cross_reference: Reactome:REACT_29691
database_cross_reference: Reactome:REACT_29764
database_cross_reference: Reactome:REACT_30149
database_cross_reference: Reactome:REACT_31024
database_cross_reference: Reactome:REACT_31919
database_cross_reference: Reactome:REACT_32546
database_cross_reference: Reactome:REACT_32932
database_cross_reference: Reactome:REACT_33572
database_cross_reference: Reactome:REACT_33874
database_cross_reference: Reactome:REACT_50018
database_cross_reference: Reactome:REACT_53588
database_cross_reference: Reactome:REACT_6729
database_cross_reference: Reactome:REACT_6738
database_cross_reference: Reactome:REACT_6750
database_cross_reference: Reactome:REACT_6769
database_cross_reference: Reactome:REACT_6798
database_cross_reference: Reactome:REACT_6869
database_cross_reference: Reactome:REACT_6936
database_cross_reference: Reactome:REACT_6939
database_cross_reference: Reactome:REACT_77532
database_cross_reference: Reactome:REACT_79188
database_cross_reference: Reactome:REACT_79450
database_cross_reference: Reactome:REACT_80432
database_cross_reference: Reactome:REACT_80571
database_cross_reference: Reactome:REACT_80896
database_cross_reference: Reactome:REACT_80988
database_cross_reference: Reactome:REACT_81803
database_cross_reference: Reactome:REACT_83095
database_cross_reference: Reactome:REACT_84829
database_cross_reference: Reactome:REACT_85561
database_cross_reference: Reactome:REACT_86410
database_cross_reference: Reactome:REACT_86739
database_cross_reference: Reactome:REACT_87233
database_cross_reference: Reactome:REACT_87449
database_cross_reference: Reactome:REACT_87590
database_cross_reference: Reactome:REACT_88085
database_cross_reference: Reactome:REACT_88384
database_cross_reference: Reactome:REACT_88529
database_cross_reference: Reactome:REACT_89355
database_cross_reference: Reactome:REACT_89439
database_cross_reference: Reactome:REACT_89725
database_cross_reference: Reactome:REACT_90512
database_cross_reference: Reactome:REACT_90809
database_cross_reference: Reactome:REACT_90838
database_cross_reference: Reactome:REACT_91184
database_cross_reference: Reactome:REACT_91302
database_cross_reference: Reactome:REACT_92527
database_cross_reference: Reactome:REACT_92644
database_cross_reference: Reactome:REACT_92706
database_cross_reference: Reactome:REACT_94983

Axiom
annotated source: DNA replication
annotated property: definition
annotated target: The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
database_cross_reference: GOC:mah

Activation of ATR in response to replication stress, Mus musculus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_100559

Activation of claspin, Xenopus tropicalis
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_101280

Activation of claspin, Bos taurus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_101497

Activation of ATR in response to replication stress, Gallus gallus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_102679

Stalling of DNA replication fork and RPA binding, Taeniopygia guttata
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_103614

Recruitment and activation of Chk1, Gallus gallus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_104547

Activation of ATR in response to replication stress, Xenopus tropicalis
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_105292

Loading of claspin onto DNA during replication origin firing, Danio rerio
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_105467

Stalling of DNA replication fork and RPA binding, Gallus gallus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_105835

Recruitment of Rad17-RFC complex to DNA, Gallus gallus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_106018

Binding of ATR-ATRIP to the RPA-ssDNA complex, Bos taurus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_106104

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Drosophila melanogaster
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_106382

Activation of claspin, Canis familiaris
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_106434

Recruitment and activation of Chk1, Canis familiaris
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_106732

Activation of ATR in response to replication stress, Danio rerio
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_107075

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Caenorhabditis elegans
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_107423

Recruitment and activation of Chk1, Bos taurus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_108461

Loading of claspin onto DNA during replication origin firing, Mus musculus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_108634

Binding of ATR-ATRIP to the RPA-ssDNA complex, Xenopus tropicalis
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_108739

Activation of ATR in response to replication stress, Bos taurus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_108768

Activation of ATR in response to replication stress, Drosophila melanogaster
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_108929

Stalling of DNA replication fork and RPA binding, Rattus norvegicus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_109137

Activation of ATR in response to replication stress, Saccharomyces cerevisiae
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_112472

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Gallus gallus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_113703

Activation of ATR in response to replication stress, Schizosaccharomyces pombe
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_29423

Binding of ATR-ATRIP to the RPA-ssDNA complex, Taeniopygia guttata
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_29444

Activation of ATR in response to replication stress, Rattus norvegicus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_29691

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Taeniopygia guttata
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_29764

Activation of claspin, Rattus norvegicus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_30149

Recruitment of Rad17-RFC complex to DNA, Xenopus tropicalis
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_31024

Loading of claspin onto DNA during replication origin firing, Rattus norvegicus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_31919

Recruitment of Rad17-RFC complex to DNA, Mus musculus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_32546

Recruitment and activation of Chk1, Taeniopygia guttata
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_32932

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_33572

Recruitment and activation of Chk1, Xenopus tropicalis
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_33874

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Rattus norvegicus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_50018

Loading of claspin onto DNA during replication origin firing, Canis familiaris
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_53588

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Homo sapiens
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_6729

Loading of claspin onto DNA during replication origin firing, Homo sapiens
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_6738

Activation of claspin, Homo sapiens
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_6750

Activation of ATR in response to replication stress, Homo sapiens
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_6769

Recruitment of Rad17-RFC complex to DNA, Homo sapiens
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_6798

Recruitment and activation of Chk1, Homo sapiens
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_6869

Stalling of DNA replication fork and RPA binding, Homo sapiens
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_6936

Binding of ATR-ATRIP to the RPA-ssDNA complex, Homo sapiens
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_6939

Stalling of DNA replication fork and RPA binding, Canis familiaris
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_77532

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Canis familiaris
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_79188

Activation of ATR in response to replication stress, Dictyostelium discoideum
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_79450

Loading of claspin onto DNA during replication origin firing, Taeniopygia guttata
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_80432

Activation of claspin, Mus musculus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_80571

Recruitment and activation of Chk1, Sus scrofa
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_80896

Loading of claspin onto DNA during replication origin firing, Bos taurus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_80988

Recruitment of Rad17-RFC complex to DNA, Canis familiaris
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_81803

Recruitment of Rad17-RFC complex to DNA, Danio rerio
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_83095

Binding of ATR-ATRIP to the RPA-ssDNA complex, Danio rerio
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_84829

Binding of ATR-ATRIP to the RPA-ssDNA complex, Rattus norvegicus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_85561

Stalling of DNA replication fork and RPA binding, Mus musculus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_86410

Recruitment and activation of Chk1, Rattus norvegicus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_86739

Binding of ATR-ATRIP to the RPA-ssDNA complex, Canis familiaris
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_87233

Recruitment of Rad17-RFC complex to DNA, Rattus norvegicus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_87449

Recruitment of Rad17-RFC complex to DNA, Bos taurus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_87590

Binding of ATR-ATRIP to the RPA-ssDNA complex, Gallus gallus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_88085

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Schizosaccharomyces pombe
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_88384

Activation of claspin, Gallus gallus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_88529

Activation of claspin, Danio rerio
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_89355

Activation of ATR in response to replication stress, Sus scrofa
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_89439

Loading of claspin onto DNA during replication origin firing, Drosophila melanogaster
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_89725

Stalling of DNA replication fork and RPA binding, Bos taurus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_90512

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Danio rerio
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_90809

Recruitment of Rad17-RFC complex to DNA, Taeniopygia guttata
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_90838

Recruitment and activation of Chk1, Danio rerio
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_91184

Activation of ATR in response to replication stress, Canis familiaris
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_91302

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Mus musculus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_92527

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Xenopus tropicalis
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_92644

Stalling of DNA replication fork and RPA binding, Danio rerio
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_92706

Stalling of DNA replication fork and RPA binding, Xenopus tropicalis
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_94983

Activation of ATR in response to replication stress, Taeniopygia guttata
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_95253

Activation of claspin, Taeniopygia guttata
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_95329

Binding of ATR-ATRIP to the RPA-ssDNA complex, Mus musculus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_96115

Recruitment and activation of Chk1, Mus musculus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_96804

Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Bos taurus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_96998

Loading of claspin onto DNA during replication origin firing, Gallus gallus
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_97204

Activation of ATR in response to replication stress, Caenorhabditis elegans
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_97726

Loading of claspin onto DNA during replication origin firing, Xenopus tropicalis
type: Axiom
annotated source: DNA replication
annotated property: database_cross_reference
annotated target: Reactome:REACT_99948

DNA repair
type: Class
subclass of: cellular response to DNA damage stimulus
definition: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
database_cross_reference: Reactome:REACT_102034
database_cross_reference: Reactome:REACT_106650
database_cross_reference: Reactome:REACT_107446
database_cross_reference: Reactome:REACT_107692
database_cross_reference: Reactome:REACT_107752
database_cross_reference: Reactome:REACT_108864
database_cross_reference: Reactome:REACT_108881
database_cross_reference: Reactome:REACT_108903
database_cross_reference: Reactome:REACT_109956
database_cross_reference: Reactome:REACT_115642
database_cross_reference: Reactome:REACT_115836
database_cross_reference: Reactome:REACT_127
database_cross_reference: Reactome:REACT_216
database_cross_reference: Reactome:REACT_29531
database_cross_reference: Reactome:REACT_29636
database_cross_reference: Reactome:REACT_78051
database_cross_reference: Reactome:REACT_82907
database_cross_reference: Reactome:REACT_83608
database_cross_reference: Reactome:REACT_83660
database_cross_reference: Reactome:REACT_84835
database_cross_reference: Reactome:REACT_85522
database_cross_reference: Reactome:REACT_86513
database_cross_reference: Reactome:REACT_86902
database_cross_reference: Reactome:REACT_88201
database_cross_reference: Reactome:REACT_88946
database_cross_reference: Reactome:REACT_89524
database_cross_reference: Reactome:REACT_90385
database_cross_reference: Reactome:REACT_90952
database_cross_reference: Reactome:REACT_91094
database_cross_reference: Reactome:REACT_91330
database_cross_reference: Reactome:REACT_91442
database_cross_reference: Reactome:REACT_91576
database_cross_reference: Reactome:REACT_92707
database_cross_reference: Reactome:REACT_93704
database_cross_reference: Reactome:REACT_94204
database_cross_reference: Reactome:REACT_94769
database_cross_reference: Reactome:REACT_95050
database_cross_reference: Reactome:REACT_95158
database_cross_reference: Reactome:REACT_96052
database_cross_reference: Reactome:REACT_96452
database_cross_reference: Reactome:REACT_99277
database_cross_reference: Wikipedia:DNA_repair
has_obo_namespace: biological_process
id: GO:0006281
in_subset: goslim pir
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: DNA repair
annotated property: definition
annotated target: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
database_cross_reference: PMID:11563486

DNA Repair, Staphylococcus aureus N315
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_102034

DNA Damage Reversal, Taeniopygia guttata
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_106650

DNA Repair, Arabidopsis thaliana
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_107446

DNA Damage Reversal, Gallus gallus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_107692

DNA Repair, Plasmodium falciparum
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_107752

DNA Damage Reversal, Rattus norvegicus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_108864

DNA Damage Reversal, Bos taurus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_108881

DNA Repair, Xenopus tropicalis
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_108903

DNA Repair, Gallus gallus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_109956

DNA repair, Gallus gallus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_115642

Fanconi Anemia Pathway in DNA repair, Gallus gallus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_115836

DNA Damage Reversal, Homo sapiens
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_127

DNA Repair, Homo sapiens
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_216

DNA Damage Reversal, Saccharomyces cerevisiae
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_29531

DNA Damage Reversal, Staphylococcus aureus N315
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_29636

DNA Damage Reversal, Canis familiaris
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_78051

DNA Repair, Oryza sativa
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_82907

DNA Damage Reversal, Caenorhabditis elegans
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_83608

DNA Repair, Escherichia coli
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_83660

DNA Damage Reversal, Dictyostelium discoideum
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_84835

DNA Repair, Mus musculus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_85522

DNA Repair, Mycobacterium tuberculosis
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_86513

DNA Repair, Danio rerio
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_86902

DNA Repair, Drosophila melanogaster
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_88201

DNA Damage Reversal, Mycobacterium tuberculosis
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_88946

DNA Damage Reversal, Drosophila melanogaster
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_89524

DNA Repair, Canis familiaris
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_90385

DNA Damage Reversal, Arabidopsis thaliana
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_90952

DNA Repair, Rattus norvegicus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_91094

DNA Repair, Bos taurus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_91330

DNA Repair, Caenorhabditis elegans
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_91442

DNA Damage Reversal, Oryza sativa
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_91576

DNA Repair, Taeniopygia guttata
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_92707

DNA Repair, Saccharomyces cerevisiae
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_93704

DNA Repair, Sus scrofa
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_94204

DNA Repair, Schizosaccharomyces pombe
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_94769

DNA Damage Reversal, Sus scrofa
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_95050

DNA Damage Reversal, Xenopus tropicalis
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_95158

DNA Repair, Dictyostelium discoideum
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_96052

DNA Damage Reversal, Danio rerio
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_96452

DNA Damage Reversal, Mus musculus
type: Axiom
annotated source: DNA repair
annotated property: database_cross_reference
annotated target: Reactome:REACT_99277

DNA recombination
type: Class
subclass of: biological_process
definition: Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
has_obo_namespace: biological_process
id: GO:0006310
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: DNA recombination
annotated property: definition
annotated target: Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
database_cross_reference: ISBN:0198506732

chromatin organization
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
has_exact_synonym: chromatin organisation
has_exact_synonym: establishment or maintenance of chromatin architecture
has_obo_namespace: biological_process
id: GO:0006325
in_subset: goslim pombe
in_subset: goslim yeast

Axiom
annotated source: chromatin organization
annotated property: definition
annotated target: Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
database_cross_reference: GOC:mah

Axiom
annotated source: chromatin organization
annotated property: has_exact_synonym
annotated target: chromatin organisation
database_cross_reference: GOC:mah

Axiom
annotated source: chromatin organization
annotated property: has_exact_synonym
annotated target: establishment or maintenance of chromatin architecture
database_cross_reference: GOC:mah

DNA-templated transcription, initiation
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
has_exact_synonym: DNA-dependent RNA polymerase complex assembly at promoter
has_exact_synonym: DNA-dependent transcription, initiation
has_exact_synonym: initiation of DNA-dependent transcription
has_exact_synonym: initiation of transcription, DNA-dependent
has_obo_namespace: biological_process
has_related_synonym: transcription initiation factor activity
has_related_synonym: transcription initiation, DNA-dependent
id: GO:0006352
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.

Axiom
annotated source: DNA-templated transcription, initiation
annotated property: definition
annotated target: Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
database_cross_reference: GOC:jid
database_cross_reference: GOC:txnOH
database_cross_reference: PMID:18280161

Axiom
annotated source: DNA-templated transcription, initiation
annotated property: has_exact_synonym
annotated target: DNA-dependent transcription, initiation
database_cross_reference: GOC:txnOH

Axiom
annotated source: DNA-templated transcription, initiation
annotated property: has_exact_synonym
annotated target: initiation of DNA-dependent transcription
database_cross_reference: GOC:jh2

Axiom
annotated source: DNA-templated transcription, initiation
annotated property: has_exact_synonym
annotated target: initiation of transcription, DNA-dependent
database_cross_reference: GOC:mah

Axiom
annotated source: DNA-templated transcription, initiation
annotated property: has_related_synonym
annotated target: transcription initiation, DNA-dependent
database_cross_reference: GOC:jh2

DNA-templated transcription, termination
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
has_broad_synonym: transcriptional complex disassembly
has_exact_synonym: DNA-dependent transcription, termination
has_exact_synonym: termination of DNA-dependent transcription
has_exact_synonym: termination of transcription, DNA-dependent
has_obo_namespace: biological_process
has_related_synonym: transcription termination factor activity
has_related_synonym: transcription termination, DNA-dependent
id: GO:0006353
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: DNA-templated transcription, termination
annotated property: definition
annotated target: The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
database_cross_reference: GOC:txnOH
database_cross_reference: ISBN:0716720094
database_cross_reference: PMID:15020047
database_cross_reference: PMID:18280161

Axiom
annotated source: DNA-templated transcription, termination
annotated property: has_exact_synonym
annotated target: DNA-dependent transcription, termination
database_cross_reference: GOC:txnOH

Axiom
annotated source: DNA-templated transcription, termination
annotated property: has_exact_synonym
annotated target: termination of DNA-dependent transcription
database_cross_reference: GOC:jh2

Axiom
annotated source: DNA-templated transcription, termination
annotated property: has_exact_synonym
annotated target: termination of transcription, DNA-dependent
database_cross_reference: GOC:mah

Axiom
annotated source: DNA-templated transcription, termination
annotated property: has_related_synonym
annotated target: transcription termination, DNA-dependent
database_cross_reference: GOC:jh2

DNA-templated transcription, elongation
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
has_broad_synonym: RNA elongation
has_exact_synonym: DNA-dependent transcription, elongation
has_exact_synonym: transcription elongation, DNA-dependent
has_exact_synonym: transcriptional elongation, DNA-dependent
has_obo_namespace: biological_process
id: GO:0006354
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: DNA-templated transcription, elongation
annotated property: definition
annotated target: The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
database_cross_reference: GOC:mah
database_cross_reference: GOC:txnOH
database_cross_reference: PMID:15020047
database_cross_reference: PMID:18280161

Axiom
annotated source: DNA-templated transcription, elongation
annotated property: has_exact_synonym
annotated target: DNA-dependent transcription, elongation
database_cross_reference: GOC:txnOH

Axiom
annotated source: DNA-templated transcription, elongation
annotated property: has_exact_synonym
annotated target: transcription elongation, DNA-dependent
database_cross_reference: GOC:jh2

transcription from RNA polymerase I promoter
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.
database_cross_reference: Reactome:REACT_100735
database_cross_reference: Reactome:REACT_100886
database_cross_reference: Reactome:REACT_110611
database_cross_reference: Reactome:REACT_110625
database_cross_reference: Reactome:REACT_1309
database_cross_reference: Reactome:REACT_28615
database_cross_reference: Reactome:REACT_28661
database_cross_reference: Reactome:REACT_30029
database_cross_reference: Reactome:REACT_31383
database_cross_reference: Reactome:REACT_32101
database_cross_reference: Reactome:REACT_39475
database_cross_reference: Reactome:REACT_77153
database_cross_reference: Reactome:REACT_78975
database_cross_reference: Reactome:REACT_84230
database_cross_reference: Reactome:REACT_92088
database_cross_reference: Reactome:REACT_95034
database_cross_reference: Reactome:REACT_95463
has_exact_synonym: transcription from Pol I promoter
has_obo_namespace: biological_process
has_related_synonym: RNA polymerase I transcription factor activity
id: GO:0006360
in_subset: goslim yeast

Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: definition
annotated target: The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.
database_cross_reference: GOC:jl
database_cross_reference: GOC:txnOH

RNA Polymerase I Transcription, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_100735

RNA Polymerase I Transcription, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_100886

RNA Polymerase I Transcription, Saccharomyces cerevisiae
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_110611

RNA Polymerase I Transcription, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_110625

RNA Polymerase I Transcription, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_1309

RNA Polymerase I Transcription, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_28615

RNA Polymerase I Transcription, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_28661

RNA Polymerase I Transcription, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_30029

RNA Polymerase I Transcription, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_31383

RNA Polymerase I Transcription, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_32101

RNA Polymerase I Transcription, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_39475

RNA Polymerase I Transcription, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_77153

RNA Polymerase I Transcription, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_78975

RNA Polymerase I Transcription, Oryza sativa
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_84230

RNA Polymerase I Transcription, Dictyostelium discoideum
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_92088

RNA Polymerase I Transcription, Schizosaccharomyces pombe
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_95034

RNA Polymerase I Transcription, Arabidopsis thaliana
type: Axiom
annotated source: transcription from RNA polymerase I promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_95463

rRNA processing
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
has_alternative_id: GO:0006365
has_narrow_synonym: 35S primary transcript processing
has_obo_namespace: biological_process
id: GO:0006364
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: rRNA processing
annotated property: definition
annotated target: Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
database_cross_reference: GOC:curators

transcription from RNA polymerase II promoter
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
has_alternative_id: GO:0032568
has_alternative_id: GO:0032569
database_cross_reference: Reactome:REACT_105738
database_cross_reference: Reactome:REACT_106213
database_cross_reference: Reactome:REACT_108012
database_cross_reference: Reactome:REACT_109421
database_cross_reference: Reactome:REACT_1366
database_cross_reference: Reactome:REACT_31558
database_cross_reference: Reactome:REACT_32943
database_cross_reference: Reactome:REACT_33538
database_cross_reference: Reactome:REACT_33583
database_cross_reference: Reactome:REACT_34720
database_cross_reference: Reactome:REACT_79747
database_cross_reference: Reactome:REACT_89454
database_cross_reference: Reactome:REACT_89916
database_cross_reference: Reactome:REACT_97471
database_cross_reference: Reactome:REACT_97536
database_cross_reference: Reactome:REACT_99228
database_cross_reference: Reactome:REACT_99748
database_cross_reference: Reactome:REACT_99950
has_exact_synonym: transcription from Pol II promoter
has_obo_namespace: biological_process
has_related_synonym: RNA polymerase II transcription factor activity
has_related_synonym: gene-specific transcription from RNA polymerase II promoter
has_related_synonym: general transcription from RNA polymerase II promoter
has_related_synonym: specific transcription from RNA polymerase II promoter
id: GO:0006366
in_subset: goslim yeast

Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: definition
annotated target: The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
database_cross_reference: GOC:jl
database_cross_reference: GOC:txnOH
database_cross_reference: ISBN:0321000382

RNA Polymerase II Transcription, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_105738

RNA Polymerase II Transcription, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_106213

RNA Polymerase II Transcription, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_108012

RNA Polymerase II Transcription, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109421

RNA Polymerase II Transcription, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_1366

RNA Polymerase II Transcription, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_31558

RNA Polymerase II Transcription, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_32943

RNA Polymerase II Transcription, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_33538

RNA Polymerase II Transcription, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_33583

RNA Polymerase II Transcription, Schizosaccharomyces pombe
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_34720

RNA Polymerase II Transcription, Plasmodium falciparum
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_79747

RNA Polymerase II Transcription, Oryza sativa
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_89454

RNA Polymerase II Transcription, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_89916

RNA Polymerase II Transcription, Arabidopsis thaliana
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_97471

RNA Polymerase II Transcription, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_97536

RNA Polymerase II Transcription, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_99228

RNA Polymerase II Transcription, Dictyostelium discoideum
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_99748

RNA Polymerase II Transcription, Saccharomyces cerevisiae
type: Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_99950

Axiom
annotated source: transcription from RNA polymerase II promoter
annotated property: has_related_synonym
annotated target: specific transcription from RNA polymerase II promoter
database_cross_reference: GOC:mah

transcription from RNA polymerase III promoter
type: Class
subclass of: biological_process
definition: The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
database_cross_reference: Reactome:REACT_100945
database_cross_reference: Reactome:REACT_101038
database_cross_reference: Reactome:REACT_101551
database_cross_reference: Reactome:REACT_101656
database_cross_reference: Reactome:REACT_101661
database_cross_reference: Reactome:REACT_101700
database_cross_reference: Reactome:REACT_101771
database_cross_reference: Reactome:REACT_101901
database_cross_reference: Reactome:REACT_102138
database_cross_reference: Reactome:REACT_102603
database_cross_reference: Reactome:REACT_102683
database_cross_reference: Reactome:REACT_103091
database_cross_reference: Reactome:REACT_103169
database_cross_reference: Reactome:REACT_103226
database_cross_reference: Reactome:REACT_103412
database_cross_reference: Reactome:REACT_103650
database_cross_reference: Reactome:REACT_103786
database_cross_reference: Reactome:REACT_104805
database_cross_reference: Reactome:REACT_105112
database_cross_reference: Reactome:REACT_105558
database_cross_reference: Reactome:REACT_105661
database_cross_reference: Reactome:REACT_106059
database_cross_reference: Reactome:REACT_1061
database_cross_reference: Reactome:REACT_106142
database_cross_reference: Reactome:REACT_106447
database_cross_reference: Reactome:REACT_106560
database_cross_reference: Reactome:REACT_106688
database_cross_reference: Reactome:REACT_106837
database_cross_reference: Reactome:REACT_107790
database_cross_reference: Reactome:REACT_107815
database_cross_reference: Reactome:REACT_108150
database_cross_reference: Reactome:REACT_108254
database_cross_reference: Reactome:REACT_108736
database_cross_reference: Reactome:REACT_108779
database_cross_reference: Reactome:REACT_109038
database_cross_reference: Reactome:REACT_109056
database_cross_reference: Reactome:REACT_109134
database_cross_reference: Reactome:REACT_109293
database_cross_reference: Reactome:REACT_109350
database_cross_reference: Reactome:REACT_109707
database_cross_reference: Reactome:REACT_109747
database_cross_reference: Reactome:REACT_109934
database_cross_reference: Reactome:REACT_109938
database_cross_reference: Reactome:REACT_110233
database_cross_reference: Reactome:REACT_110354
database_cross_reference: Reactome:REACT_110533
database_cross_reference: Reactome:REACT_110624
database_cross_reference: Reactome:REACT_112623
database_cross_reference: Reactome:REACT_112804
database_cross_reference: Reactome:REACT_113692
database_cross_reference: Reactome:REACT_114988
database_cross_reference: Reactome:REACT_1179
database_cross_reference: Reactome:REACT_118261
database_cross_reference: Reactome:REACT_118310
database_cross_reference: Reactome:REACT_118481
database_cross_reference: Reactome:REACT_1241
database_cross_reference: Reactome:REACT_1371
database_cross_reference: Reactome:REACT_1374
database_cross_reference: Reactome:REACT_1616
database_cross_reference: Reactome:REACT_2178
database_cross_reference: Reactome:REACT_2210
database_cross_reference: Reactome:REACT_2248
database_cross_reference: Reactome:REACT_2251
database_cross_reference: Reactome:REACT_251
database_cross_reference: Reactome:REACT_28871
database_cross_reference: Reactome:REACT_28926
database_cross_reference: Reactome:REACT_29249
database_cross_reference: Reactome:REACT_29589
database_cross_reference: Reactome:REACT_30206
database_cross_reference: Reactome:REACT_30383
database_cross_reference: Reactome:REACT_30530
database_cross_reference: Reactome:REACT_30710
database_cross_reference: Reactome:REACT_30749
database_cross_reference: Reactome:REACT_30852
database_cross_reference: Reactome:REACT_30868
database_cross_reference: Reactome:REACT_31576
database_cross_reference: Reactome:REACT_31708

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_43442

RNA Polymerase III Promoter Opening at Type 1 Promoters, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_50555

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_76991

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_77583

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_77734

RNA Polymerase III Productive Transcription, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_77763

Initiation of RNA Polymerase III Productive Transcription, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_77942

Resumption of RNA Polymerase III Productive Transcription, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_78034

Resumption of RNA Polymerase III Productive Transcription, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_78101

RNA Polymerase III Promoter Opening at Type 1 Promoters, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_78330

RNA Polymerase III Productive Transcription, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_78526

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_79030

Resumption of RNA Polymerase III Productive Transcription, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_79212

RNA Polymerase III Transcription, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_79230

RNA Polymerase III Promoter Opening at Type 1 Promoters, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_796

RNA Polymerase III Transcription, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_79674

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_79928

RNA Polymerase III Productive Transcription, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_80506

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_80530

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Arabidopsis thaliana
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_80924

RNA Polymerase III Productive Transcription, Schizosaccharomyces pombe
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_81033

Resumption of RNA Polymerase III Productive Transcription, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_81681

RNA Polymerase III Productive Transcription, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_82476

RNA Polymerase III Transcription, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_82823

RNA Polymerase III Transcription, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_82958

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_83072

Resumption of RNA Polymerase III Productive Transcription, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_83162

RNA Polymerase III Transcription, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_83237

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_83573

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_83679

RNA Polymerase III Promoter Opening at Type 1 Promoters, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_83791

RNA Polymerase III Transcription, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_84005

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_84052

RNA Polymerase III Transcription, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_84174

RNA Polymerase III Transcription, Arabidopsis thaliana
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_84770

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_85321

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_85665

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_85700

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_85938

Initiation of RNA Polymerase III Productive Transcription, Dictyostelium discoideum
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_86188

RNA Polymerase III Productive Transcription, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_86214

Resumption of RNA Polymerase III Productive Transcription, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_86477

RNA Polymerase III Productive Transcription, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_86680

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_87495

RNA Polymerase III Promoter Opening at Type 1 Promoters, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_88180

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_88328

Initiation of RNA Polymerase III Productive Transcription, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_89113

RNA Polymerase III Productive Transcription, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_89159

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_89744

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_90232

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_90884

Initiation of RNA Polymerase III Productive Transcription, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_90929

Initiation of RNA Polymerase III Productive Transcription, Arabidopsis thaliana
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_90945

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_90947

RNA Polymerase III Transcription, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_91182

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_91223

Initiation of RNA Polymerase III Productive Transcription, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_91433

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_92510

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_92565

RNA Polymerase III Promoter Opening at Type 1 Promoters, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_92674

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_92814

RNA Polymerase III Transcription, Oryza sativa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_92970

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_93003

RNA Polymerase III Productive Transcription, Oryza sativa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_93041

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Oryza sativa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_93262

Resumption of RNA Polymerase III Productive Transcription, Arabidopsis thaliana
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_93305

RNA Polymerase III Transcription, Dictyostelium discoideum
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_93548

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Dictyostelium discoideum
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_93709

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_93754

RNA Polymerase III Productive Transcription, Arabidopsis thaliana
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_93859

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_94189

RNA Polymerase III Transcription, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_94421

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_94567

Resumption of RNA Polymerase III Productive Transcription, Oryza sativa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_94753

Resumption of RNA Polymerase III Productive Transcription, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_96798

Initiation of RNA Polymerase III Productive Transcription, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_97406

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_97559

RNA Polymerase III Productive Transcription, Dictyostelium discoideum
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_98079

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_98254

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_98466

Resumption of RNA Polymerase III Productive Transcription, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_98470

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_98660

RNA Polymerase III Productive Transcription, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_98770

RNA Polymerase III Promoter Opening at Type 1 Promoters, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_99332

Initiation of RNA Polymerase III Productive Transcription, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_99492

Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: definition
annotated target: The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
database_cross_reference: GOC:jl
database_cross_reference: GOC:txnOH

Initiation of RNA Polymerase III Productive Transcription, Schizosaccharomyces pombe
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_100945

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_101038

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_101551

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_101656

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_101661

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_101700

RNA Polymerase III Promoter Opening at Type 1 Promoters, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_101771

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_101901

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_102138

RNA Polymerase III Transcription, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_102603

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_102683

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_103091

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_103169

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_103226

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_103412

RNA Polymerase III Transcription, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_103650

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_103786

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Schizosaccharomyces pombe
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_104805

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_105112

Resumption of RNA Polymerase III Productive Transcription, Dictyostelium discoideum
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_105558

RNA Polymerase III Transcription, Schizosaccharomyces pombe
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_105661

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_106059

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_1061

Initiation of RNA Polymerase III Productive Transcription, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_106142

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_106447

Initiation of RNA Polymerase III Productive Transcription, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_106560

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_106688

Resumption of RNA Polymerase III Productive Transcription, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_106837

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_107790

RNA Polymerase III Transcription, Saccharomyces cerevisiae
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_107815

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Gallus gallus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_108150

RNA Polymerase III Promoter Opening at Type 1 Promoters, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_108254

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Sus scrofa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_108736

Initiation of RNA Polymerase III Productive Transcription, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_108779

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109038

Resumption of RNA Polymerase III Productive Transcription, Schizosaccharomyces pombe
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109056

Initiation of RNA Polymerase III Productive Transcription, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109134

RNA Polymerase III Productive Transcription, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109293

Resumption of RNA Polymerase III Productive Transcription, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109350

RNA Polymerase III Productive Transcription, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109707

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109747

RNA Polymerase III Promoter Opening at Type 1 Promoters, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109934

Initiation of RNA Polymerase III Productive Transcription, Oryza sativa
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_109938

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_110233

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_110354

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_110533

Initiation of RNA Polymerase III Productive Transcription, Danio rerio
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_110624

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_112623

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Dictyostelium discoideum
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_112804

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Dictyostelium discoideum
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_113692

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_114988

Initiation of RNA Polymerase III Productive Transcription, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_1179

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_118261

RNA Polymerase III Promoter Opening at Type 1 Promoters, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_118310

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Caenorhabditis elegans
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_118481

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_1241

RNA Polymerase III Transcription, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_1371

Resumption of RNA Polymerase III Productive Transcription, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_1374

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_1616

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_2178

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_2210

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_2248

RNA Polymerase III Productive Transcription, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_2251

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Homo sapiens
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_251

RNA Polymerase III Productive Transcription, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_28871

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_28926

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_29249

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_29589

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_30206

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_30383

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_30530

RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Taeniopygia guttata
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_30710

RNA Polymerase III Promoter Opening at Type 1 Promoters, Rattus norvegicus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_30749

RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_30852

RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_30868

Resumption of RNA Polymerase III Productive Transcription, Xenopus tropicalis
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_31576

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Drosophila melanogaster
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_31708

RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Mus musculus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_32551

RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Canis familiaris
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_32580

RNA Polymerase III Abortive Initiation At Type 1 Open Promoters, Bos taurus
type: Axiom
annotated source: transcription from RNA polymerase III promoter
annotated property: database_cross_reference
annotated target: Reactome:REACT_34048

mRNA processing
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
database_cross_reference: Reactome:REACT_100203
database_cross_reference: Reactome:REACT_107308
database_cross_reference: Reactome:REACT_109953
database_cross_reference: Reactome:REACT_113864
database_cross_reference: Reactome:REACT_114358
database_cross_reference: Reactome:REACT_115262
database_cross_reference: Reactome:REACT_1768
database_cross_reference: Reactome:REACT_32742
database_cross_reference: Reactome:REACT_33642
database_cross_reference: Reactome:REACT_82691
database_cross_reference: Reactome:REACT_90366
database_cross_reference: Reactome:REACT_91511
database_cross_reference: Reactome:REACT_93186
database_cross_reference: Reactome:REACT_94083
database_cross_reference: Reactome:REACT_96661
database_cross_reference: Reactome:REACT_97412
database_cross_reference: Reactome:REACT_97436
has_obo_namespace: biological_process
has_related_synonym: mRNA maturation
id: GO:0006397
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: mRNA processing
annotated property: definition
annotated target: Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
database_cross_reference: GOC:mah

Processing of Capped Intronless Pre-mRNA, Dictyostelium discoideum
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_100203

Processing of Capped Intronless Pre-mRNA, Xenopus tropicalis
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_107308

Processing of Capped Intronless Pre-mRNA, Canis familiaris
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_109953

Processing of Capped Intronless Pre-mRNA, Saccharomyces cerevisiae
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_113864

Processing of Capped Intronless Pre-mRNA, Schizosaccharomyces pombe
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_114358

Processing of Capped Intronless Pre-mRNA, Arabidopsis thaliana
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_115262

Processing of Capped Intronless Pre-mRNA, Homo sapiens
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_1768

Processing of Capped Intronless Pre-mRNA, Bos taurus
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_32742

Processing of Capped Intronless Pre-mRNA, Caenorhabditis elegans
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_33642

Processing of Capped Intronless Pre-mRNA, Gallus gallus
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_82691

Processing of Capped Intronless Pre-mRNA, Drosophila melanogaster
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_90366

Processing of Capped Intronless Pre-mRNA, Danio rerio
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_91511

Processing of Capped Intronless Pre-mRNA, Sus scrofa
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_93186

Processing of Capped Intronless Pre-mRNA, Taeniopygia guttata
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_94083

Processing of Capped Intronless Pre-mRNA, Oryza sativa
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_96661

Processing of Capped Intronless Pre-mRNA, Rattus norvegicus
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_97412

Processing of Capped Intronless Pre-mRNA, Mus musculus
type: Axiom
annotated source: mRNA processing
annotated property: database_cross_reference
annotated target: Reactome:REACT_97436

RNA catabolic process
type: Class
subclass of: biological_process
definition: The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
has_exact_synonym: RNA breakdown
has_exact_synonym: RNA catabolism
has_exact_synonym: RNA degradation
has_obo_namespace: biological_process
id: GO:0006401
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: RNA catabolic process
annotated property: definition
annotated target: The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
database_cross_reference: ISBN:0198506732

translational initiation
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
has_alternative_id: GO:0006440
has_alternative_id: GO:0006454
has_broad_synonym: biopolymerisation
has_broad_synonym: biopolymerization
has_broad_synonym: protein synthesis initiation
database_cross_reference: Reactome:REACT_101789
database_cross_reference: Reactome:REACT_104290
database_cross_reference: Reactome:REACT_2159
database_cross_reference: Reactome:REACT_29447
database_cross_reference: Reactome:REACT_30389
database_cross_reference: Reactome:REACT_33969
database_cross_reference: Reactome:REACT_34354
database_cross_reference: Reactome:REACT_77252
database_cross_reference: Reactome:REACT_79705
database_cross_reference: Reactome:REACT_85780
database_cross_reference: Reactome:REACT_88031
database_cross_reference: Reactome:REACT_91066
database_cross_reference: Reactome:REACT_95293
database_cross_reference: Reactome:REACT_95552
database_cross_reference: Reactome:REACT_95685
database_cross_reference: Reactome:REACT_97707
database_cross_reference: Reactome:REACT_98138
database_cross_reference: Reactome:REACT_99004
has_exact_synonym: translation initiation
has_obo_namespace: biological_process
id: GO:0006413
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: translational initiation
annotated property: definition
annotated target: The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
database_cross_reference: ISBN:019879276X

Eukaryotic Translation Initiation, Gallus gallus
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_101789

Eukaryotic Translation Initiation, Xenopus tropicalis
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_104290

Eukaryotic Translation Initiation, Homo sapiens
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_2159

Eukaryotic Translation Initiation, Dictyostelium discoideum
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_29447

Eukaryotic Translation Initiation, Oryza sativa
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_30389

Eukaryotic Translation Initiation, Caenorhabditis elegans
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_33969

Eukaryotic Translation Initiation, Taeniopygia guttata
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_34354

Eukaryotic Translation Initiation, Drosophila melanogaster
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_77252

Eukaryotic Translation Initiation, Rattus norvegicus
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_79705

Eukaryotic Translation Initiation, Bos taurus
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_85780

Eukaryotic Translation Initiation, Schizosaccharomyces pombe
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_88031

Eukaryotic Translation Initiation, Arabidopsis thaliana
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_91066

Eukaryotic Translation Initiation, Plasmodium falciparum
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_95293

Eukaryotic Translation Initiation, Mus musculus
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_95552

Eukaryotic Translation Initiation, Canis familiaris
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_95685

Eukaryotic Translation Initiation, Sus scrofa
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_97707

Eukaryotic Translation Initiation, Saccharomyces cerevisiae
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_98138

Eukaryotic Translation Initiation, Danio rerio
type: Axiom
annotated source: translational initiation
annotated property: database_cross_reference
annotated target: Reactome:REACT_99004

translational elongation
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
has_alternative_id: GO:0006442
has_alternative_id: GO:0006455
has_broad_synonym: protein synthesis elongation
database_cross_reference: Reactome:REACT_100207
database_cross_reference: Reactome:REACT_100561
database_cross_reference: Reactome:REACT_101290
database_cross_reference: Reactome:REACT_101737
database_cross_reference: Reactome:REACT_102082
database_cross_reference: Reactome:REACT_103580
database_cross_reference: Reactome:REACT_108124
database_cross_reference: Reactome:REACT_108677
database_cross_reference: Reactome:REACT_108858
database_cross_reference: Reactome:REACT_1477
database_cross_reference: Reactome:REACT_30678
database_cross_reference: Reactome:REACT_31079
database_cross_reference: Reactome:REACT_80015
database_cross_reference: Reactome:REACT_80831
database_cross_reference: Reactome:REACT_81624
database_cross_reference: Reactome:REACT_82124
database_cross_reference: Reactome:REACT_88049
database_cross_reference: Reactome:REACT_93503
database_cross_reference: Reactome:REACT_96070
has_exact_synonym: translation elongation
has_obo_namespace: biological_process
id: GO:0006414
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: translational elongation
annotated property: definition
annotated target: The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
database_cross_reference: GOC:ems

Eukaryotic Translation Elongation, Dictyostelium discoideum
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_100207

Eukaryotic Translation Elongation, Canis familiaris
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_100561

Eukaryotic Translation Elongation, Gallus gallus
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_101290

Eukaryotic Translation Elongation, Escherichia coli
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_101737

Eukaryotic Translation Elongation, Mus musculus
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_102082

Eukaryotic Translation Elongation, Danio rerio
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_103580

Eukaryotic Translation Elongation, Xenopus tropicalis
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_108124

Eukaryotic Translation Elongation, Taeniopygia guttata
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_108677

Eukaryotic Translation Elongation, Caenorhabditis elegans
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_108858

Eukaryotic Translation Elongation, Homo sapiens
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_1477

Eukaryotic Translation Elongation, Arabidopsis thaliana
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_30678

Eukaryotic Translation Elongation, Sus scrofa
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_31079

Eukaryotic Translation Elongation, Bos taurus
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_80015

Eukaryotic Translation Elongation, Rattus norvegicus
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_80831

Eukaryotic Translation Elongation, Drosophila melanogaster
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_81624

Eukaryotic Translation Elongation, Saccharomyces cerevisiae
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_82124

Eukaryotic Translation Elongation, Schizosaccharomyces pombe
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_88049

Eukaryotic Translation Elongation, Oryza sativa
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_93503

Eukaryotic Translation Elongation, Plasmodium falciparum
type: Axiom
annotated source: translational elongation
annotated property: database_cross_reference
annotated target: Reactome:REACT_96070

regulation of translation
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: regulates
  some values from: biological_process
definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
has_alternative_id: GO:0006445
has_exact_synonym: regulation of protein anabolism
has_exact_synonym: regulation of protein biosynthesis
has_exact_synonym: regulation of protein formation
has_exact_synonym: regulation of protein synthesis
has_obo_namespace: biological_process
id: GO:0006417
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: regulation of translation
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
database_cross_reference: GOC:isa_complete

tRNA aminoacylation for protein translation
type: Class
subclass of: cellular amino acid metabolic process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis.
database_cross_reference: MetaCyc:TRNA-CHARGING-PWY
database_cross_reference: Reactome:REACT_100041
database_cross_reference: Reactome:REACT_100416
database_cross_reference: Reactome:REACT_100487
database_cross_reference: Reactome:REACT_102312
database_cross_reference: Reactome:REACT_103116
database_cross_reference: Reactome:REACT_103136
database_cross_reference: Reactome:REACT_103575
database_cross_reference: Reactome:REACT_103831
database_cross_reference: Reactome:REACT_104381
database_cross_reference: Reactome:REACT_106785
database_cross_reference: Reactome:REACT_107047
database_cross_reference: Reactome:REACT_107203
database_cross_reference: Reactome:REACT_107248
database_cross_reference: Reactome:REACT_107617
database_cross_reference: Reactome:REACT_107708
database_cross_reference: Reactome:REACT_109699
database_cross_reference: Reactome:REACT_111025
database_cross_reference: Reactome:REACT_15302
database_cross_reference: Reactome:REACT_15306
database_cross_reference: Reactome:REACT_15482
database_cross_reference: Reactome:REACT_28311
database_cross_reference: Reactome:REACT_28868
database_cross_reference: Reactome:REACT_29481
database_cross_reference: Reactome:REACT_30365
database_cross_reference: Reactome:REACT_31574
database_cross_reference: Reactome:REACT_31839
database_cross_reference: Reactome:REACT_33855
database_cross_reference: Reactome:REACT_34656
database_cross_reference: Reactome:REACT_40380
database_cross_reference: Reactome:REACT_59282
database_cross_reference: Reactome:REACT_78082
database_cross_reference: Reactome:REACT_79804
database_cross_reference: Reactome:REACT_80723
database_cross_reference: Reactome:REACT_81425
database_cross_reference: Reactome:REACT_81996
database_cross_reference: Reactome:REACT_82393
database_cross_reference: Reactome:REACT_82791
database_cross_reference: Reactome:REACT_84562
database_cross_reference: Reactome:REACT_84847
database_cross_reference: Reactome:REACT_85758
database_cross_reference: Reactome:REACT_85924
database_cross_reference: Reactome:REACT_86341
database_cross_reference: Reactome:REACT_87556
database_cross_reference: Reactome:REACT_88061
database_cross_reference: Reactome:REACT_88111
database_cross_reference: Reactome:REACT_88297
database_cross_reference: Reactome:REACT_89110
database_cross_reference: Reactome:REACT_89459
database_cross_reference: Reactome:REACT_89892
database_cross_reference: Reactome:REACT_91438
database_cross_reference: Reactome:REACT_91939
database_cross_reference: Reactome:REACT_93083
database_cross_reference: Reactome:REACT_93096
database_cross_reference: Reactome:REACT_93590
database_cross_reference: Reactome:REACT_95057
database_cross_reference: Reactome:REACT_95362
database_cross_reference: Reactome:REACT_95636
database_cross_reference: Reactome:REACT_95656
database_cross_reference: Reactome:REACT_97943
database_cross_reference: Reactome:REACT_98561
database_cross_reference: Reactome:REACT_98686
database_cross_reference: Reactome:REACT_99090
database_cross_reference: Reactome:REACT_99901
has_narrow_synonym: tRNA charging
has_obo_namespace: biological_process
id: GO:0006418
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: definition
annotated target: The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis.
database_cross_reference: GOC:ma

Mitochondrial tRNA aminoacylation, Escherichia coli
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_100041

Cytosolic tRNA aminoacylation, Sus scrofa
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_100416

Mitochondrial tRNA aminoacylation, Drosophila melanogaster
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_100487

tRNA Aminoacylation, Plasmodium falciparum
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_102312

tRNA Aminoacylation, Canis familiaris
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_103116

Mitochondrial tRNA aminoacylation, Taeniopygia guttata
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_103136

tRNA Aminoacylation, Arabidopsis thaliana
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_103575

Mitochondrial tRNA aminoacylation, Oryza sativa
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_103831

Cytosolic tRNA aminoacylation, Staphylococcus aureus N315
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_104381

Cytosolic tRNA aminoacylation, Schizosaccharomyces pombe
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_106785

tRNA Aminoacylation, Escherichia coli
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_107047

Cytosolic tRNA aminoacylation, Plasmodium falciparum
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_107203

tRNA Aminoacylation, Danio rerio
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_107248

Mitochondrial tRNA aminoacylation, Rattus norvegicus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_107617

tRNA Aminoacylation, Schizosaccharomyces pombe
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_107708

tRNA Aminoacylation, Xenopus tropicalis
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_109699

Cytosolic tRNA aminoacylation, Caenorhabditis elegans
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_111025

Mitochondrial tRNA aminoacylation, Homo sapiens
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_15302

Cytosolic tRNA aminoacylation, Homo sapiens
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_15306

tRNA Aminoacylation, Homo sapiens
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_15482

tRNA Aminoacylation, Staphylococcus aureus N315
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_28311

tRNA Aminoacylation, Bos taurus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_28868

tRNA Aminoacylation, Mycobacterium tuberculosis
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_29481

Cytosolic tRNA aminoacylation, Dictyostelium discoideum
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_30365

Cytosolic tRNA aminoacylation, Oryza sativa
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_31574

Cytosolic tRNA aminoacylation, Bos taurus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_31839

tRNA Aminoacylation, Caenorhabditis elegans
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_33855

Mitochondrial tRNA aminoacylation, Caenorhabditis elegans
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_34656

tRNA Aminoacylation, Rattus norvegicus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_40380

Cytosolic tRNA aminoacylation, Mus musculus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_59282

tRNA Aminoacylation, Mus musculus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_78082

Mitochondrial tRNA aminoacylation, Dictyostelium discoideum
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_79804

tRNA Aminoacylation, Drosophila melanogaster
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_80723

tRNA Aminoacylation, Sus scrofa
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_81425

Mitochondrial tRNA aminoacylation, Saccharomyces cerevisiae
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_81996

Cytosolic tRNA aminoacylation, Escherichia coli
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_82393

Cytosolic tRNA aminoacylation, Danio rerio
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_82791

Mitochondrial tRNA aminoacylation, Bos taurus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_84562

Cytosolic tRNA aminoacylation, Xenopus tropicalis
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_84847

tRNA Aminoacylation, Taeniopygia guttata
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_85758

Cytosolic tRNA aminoacylation, Taeniopygia guttata
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_85924

Mitochondrial tRNA aminoacylation, Mycobacterium tuberculosis
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_86341

Cytosolic tRNA aminoacylation, Drosophila melanogaster
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_87556

Cytosolic tRNA aminoacylation, Rattus norvegicus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_88061

Mitochondrial tRNA aminoacylation, Arabidopsis thaliana
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_88111

Cytosolic tRNA aminoacylation, Gallus gallus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_88297

Cytosolic tRNA aminoacylation, Canis familiaris
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_89110

tRNA Aminoacylation, Oryza sativa
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_89459

Mitochondrial tRNA aminoacylation, Xenopus tropicalis
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_89892

Mitochondrial tRNA aminoacylation, Staphylococcus aureus N315
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_91438

Mitochondrial tRNA aminoacylation, Mus musculus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_91939

Mitochondrial tRNA aminoacylation, Danio rerio
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_93083

tRNA Aminoacylation, Gallus gallus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_93096

Cytosolic tRNA aminoacylation, Saccharomyces cerevisiae
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_93590

Cytosolic tRNA aminoacylation, Mycobacterium tuberculosis
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_95057

Mitochondrial tRNA aminoacylation, Plasmodium falciparum
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_95362

Mitochondrial tRNA aminoacylation, Gallus gallus
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_95636

tRNA Aminoacylation, Dictyostelium discoideum
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_95656

Mitochondrial tRNA aminoacylation, Sus scrofa
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_97943

Mitochondrial tRNA aminoacylation, Schizosaccharomyces pombe
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_98561

Cytosolic tRNA aminoacylation, Arabidopsis thaliana
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_98686

tRNA Aminoacylation, Saccharomyces cerevisiae
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_99090

Mitochondrial tRNA aminoacylation, Canis familiaris
type: Axiom
annotated source: tRNA aminoacylation for protein translation
annotated property: database_cross_reference
annotated target: Reactome:REACT_99901

protein folding
type: Class
subclass of: biological_process
definition: The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
has_alternative_id: GO:0007022
has_alternative_id: GO:0007024
has_alternative_id: GO:0007025
database_cross_reference: Reactome:REACT_100411
database_cross_reference: Reactome:REACT_104912
database_cross_reference: Reactome:REACT_105663
database_cross_reference: Reactome:REACT_106009
database_cross_reference: Reactome:REACT_106427
database_cross_reference: Reactome:REACT_106894
database_cross_reference: Reactome:REACT_106927
database_cross_reference: Reactome:REACT_107029
database_cross_reference: Reactome:REACT_108248
database_cross_reference: Reactome:REACT_109411
database_cross_reference: Reactome:REACT_110417
database_cross_reference: Reactome:REACT_16956
database_cross_reference: Reactome:REACT_17001
database_cross_reference: Reactome:REACT_17004
database_cross_reference: Reactome:REACT_17056
database_cross_reference: Reactome:REACT_23878
database_cross_reference: Reactome:REACT_30906
database_cross_reference: Reactome:REACT_32155
database_cross_reference: Reactome:REACT_32255
database_cross_reference: Reactome:REACT_33395
database_cross_reference: Reactome:REACT_77627
database_cross_reference: Reactome:REACT_77963
database_cross_reference: Reactome:REACT_78530
database_cross_reference: Reactome:REACT_81155
database_cross_reference: Reactome:REACT_83906
database_cross_reference: Reactome:REACT_85492
database_cross_reference: Reactome:REACT_85496
database_cross_reference: Reactome:REACT_86318
database_cross_reference: Reactome:REACT_91676
database_cross_reference: Reactome:REACT_92785
database_cross_reference: Reactome:REACT_92961
database_cross_reference: Reactome:REACT_92981
database_cross_reference: Reactome:REACT_94123
database_cross_reference: Reactome:REACT_94443
database_cross_reference: Reactome:REACT_94772
database_cross_reference: Reactome:REACT_96773
database_cross_reference: Reactome:REACT_97016
database_cross_reference: Reactome:REACT_97220
database_cross_reference: Reactome:REACT_98132
database_cross_reference: Wikipedia:Protein_folding
has_narrow_synonym: alpha-tubulin folding
has_narrow_synonym: beta-tubulin folding
has_narrow_synonym: chaperonin-mediated tubulin folding
has_obo_namespace: biological_process
has_related_synonym: chaperone activity
has_related_synonym: chaperonin ATPase activity
has_related_synonym: co-chaperone activity
has_related_synonym: co-chaperonin activity
has_related_synonym: glycoprotein-specific chaperone activity
has_related_synonym: non-chaperonin molecular chaperone ATPase activity
has_related_synonym: protein complex assembly, multichaperone pathway
id: GO:0006457
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: protein folding
annotated property: definition
annotated target: The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
database_cross_reference: GOC:go_curators
database_cross_reference: GOC:rb

Chaperonin-mediated protein folding, Arabidopsis thaliana
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_100411

Chaperonin-mediated protein folding, Caenorhabditis elegans
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_104912

Chaperonin-mediated protein folding, Rattus norvegicus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_105663

Chaperonin-mediated protein folding, Canis familiaris
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_106009

Chaperonin-mediated protein folding, Mus musculus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_106427

Formation of tubulin folding intermediates by CCT/TriC, Canis familiaris
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_106894

Chaperonin-mediated protein folding, Drosophila melanogaster
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_106927

Formation of tubulin folding intermediates by CCT/TriC, Drosophila melanogaster
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_107029

Chaperonin-mediated protein folding, Gallus gallus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_108248

Formation of tubulin folding intermediates by CCT/TriC, Bos taurus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_109411

Formation of tubulin folding intermediates by CCT/TriC, Rattus norvegicus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_110417

Formation of tubulin folding intermediates by CCT/TriC, Homo sapiens
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_16956

Formation of tubulin folding intermediates by CCT/TriC, Mus musculus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_17001

Chaperonin-mediated protein folding, Homo sapiens
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_17004

Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding, Bos taurus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_17056

N-glycan trimming in the ER and Calnexin/Calreticulin cycle, Homo sapiens
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_23878

Chaperonin-mediated protein folding, Oryza sativa
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_30906

Chaperonin-mediated protein folding, Saccharomyces cerevisiae
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_32155

Chaperonin-mediated protein folding, Schizosaccharomyces pombe
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_32255

Formation of tubulin folding intermediates by CCT/TriC, Mus musculus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_33395

Chaperonin-mediated protein folding, Plasmodium falciparum
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_77627

Formation of tubulin folding intermediates by CCT/TriC, Saccharomyces cerevisiae
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_77963

Formation of tubulin folding intermediates by CCT/TriC, Gallus gallus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_78530

Formation of tubulin folding intermediates by CCT/TriC, Caenorhabditis elegans
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_81155

Chaperonin-mediated protein folding, Dictyostelium discoideum
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_83906

Formation of tubulin folding intermediates by CCT/TriC, Sus scrofa
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_85492

Formation of tubulin folding intermediates by CCT/TriC, Plasmodium falciparum
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_85496

Formation of tubulin folding intermediates by CCT/TriC, Arabidopsis thaliana
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_86318

Formation of tubulin folding intermediates by CCT/TriC, Schizosaccharomyces pombe
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_91676

Formation of tubulin folding intermediates by CCT/TriC, Dictyostelium discoideum
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_92785

Chaperonin-mediated protein folding, Xenopus tropicalis
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_92961

Chaperonin-mediated protein folding, Taeniopygia guttata
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_92981

Formation of tubulin folding intermediates by CCT/TriC, Taeniopygia guttata
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_94123

Formation of tubulin folding intermediates by CCT/TriC, Danio rerio
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_94443

Chaperonin-mediated protein folding, Sus scrofa
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_94772

Chaperonin-mediated protein folding, Danio rerio
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_96773

Chaperonin-mediated protein folding, Bos taurus
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_97016

Formation of tubulin folding intermediates by CCT/TriC, Xenopus tropicalis
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_97220

Formation of tubulin folding intermediates by CCT/TriC, Oryza sativa
type: Axiom
annotated source: protein folding
annotated property: database_cross_reference
annotated target: Reactome:REACT_98132

Axiom
annotated source: protein folding
annotated property: has_narrow_synonym
annotated target: alpha-tubulin folding
database_cross_reference: GOC:mah

Axiom
annotated source: protein folding
annotated property: has_narrow_synonym
annotated target: beta-tubulin folding
database_cross_reference: GOC:mah

Axiom
annotated source: protein folding
annotated property: has_narrow_synonym
annotated target: chaperonin-mediated tubulin folding
database_cross_reference: GOC:mah

protein phosphorylation
type: Class
subclass of: biological_process
definition: The process of introducing a phosphate group on to a protein.
has_exact_synonym: protein amino acid phosphorylation
has_obo_namespace: biological_process
id: GO:0006468
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: protein phosphorylation
annotated property: definition
annotated target: The process of introducing a phosphate group on to a protein.
database_cross_reference: GOC:hb

Axiom
annotated source: protein phosphorylation
annotated property: has_exact_synonym
annotated target: protein amino acid phosphorylation
database_cross_reference: GOC:bf

protein dephosphorylation
type: Class
subclass of: biological_process
definition: The process of removing one or more phosphoric residues from a protein.
has_exact_synonym: protein amino acid dephosphorylation
has_obo_namespace: biological_process
id: GO:0006470
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: protein dephosphorylation
annotated property: definition
annotated target: The process of removing one or more phosphoric residues from a protein.
database_cross_reference: GOC:hb

Axiom
annotated source: protein dephosphorylation
annotated property: has_exact_synonym
annotated target: protein amino acid dephosphorylation
database_cross_reference: GOC:bf

protein glycosylation
type: Class
subclass of: carbohydrate metabolic process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
has_exact_synonym: protein amino acid glycosylation
has_obo_namespace: biological_process
id: GO:0006486
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: protein glycosylation
annotated property: definition
annotated target: A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
database_cross_reference: GOC:curators
database_cross_reference: GOC:pr

Axiom
annotated source: protein glycosylation
annotated property: has_exact_synonym
annotated target: protein amino acid glycosylation
database_cross_reference: GOC:bf

protein lipidation
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The covalent attachment of lipid groups to an amino acid in a protein.
has_alternative_id: GO:0042050
database_cross_reference: RESID:AA0059
database_cross_reference: RESID:AA0060
database_cross_reference: RESID:AA0077
database_cross_reference: RESID:AA0078
database_cross_reference: RESID:AA0079
database_cross_reference: RESID:AA0080
database_cross_reference: RESID:AA0102
database_cross_reference: RESID:AA0103
database_cross_reference: RESID:AA0104
database_cross_reference: RESID:AA0106
database_cross_reference: RESID:AA0107
database_cross_reference: RESID:AA0158
database_cross_reference: RESID:AA0159
database_cross_reference: RESID:AA0160
database_cross_reference: RESID:AA0161
database_cross_reference: RESID:AA0162
database_cross_reference: RESID:AA0163
database_cross_reference: RESID:AA0166
database_cross_reference: RESID:AA0223
database_cross_reference: RESID:AA0290
database_cross_reference: RESID:AA0307
database_cross_reference: RESID:AA0308
database_cross_reference: RESID:AA0309
database_cross_reference: RESID:AA0316
has_exact_synonym: lipid:protein modification
has_exact_synonym: protein amino acid lipidation
has_obo_namespace: biological_process
id: GO:0006497
in_subset: goslim yeast
in_subset: gosubset prok
comment: For non-covalent interactions with a lipid, consider instead the term 'lipid binding ; GO:0008289' and its children.

Axiom
annotated source: protein lipidation
annotated property: definition
annotated target: The covalent attachment of lipid groups to an amino acid in a protein.
database_cross_reference: GOC:jl

Axiom
annotated source: protein lipidation
annotated property: has_exact_synonym
annotated target: protein amino acid lipidation
database_cross_reference: GOC:bf

cellular amino acid metabolic process
type: Class
subclass of: biological_process
definition: The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
has_alternative_id: GO:0006519
database_cross_reference: Reactome:REACT_116093
has_exact_synonym: amino acid and derivative metabolism
has_exact_synonym: amino acid metabolic process
has_exact_synonym: cellular amino acid and derivative metabolic process
has_exact_synonym: cellular amino acid metabolism
has_obo_namespace: biological_process
id: GO:0006520
in_subset: goslim aspergillus
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cellular amino acid metabolic process
annotated property: definition
annotated target: The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
database_cross_reference: CHEBI:33709
database_cross_reference: GOC:curators
database_cross_reference: ISBN:0198506732

Amino acid metabolism, Gallus gallus
type: Axiom
annotated source: cellular amino acid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_116093

Axiom
annotated source: cellular amino acid metabolic process
annotated property: has_exact_synonym
annotated target: amino acid and derivative metabolism
database_cross_reference: GOC:curators

Axiom
annotated source: cellular amino acid metabolic process
annotated property: has_exact_synonym
annotated target: amino acid metabolic process
database_cross_reference: GOC:curators

protein targeting
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
subclass of: Restriction
  on property: occurs in
  some values from: cellular_component
definition: The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
database_cross_reference: Wikipedia:Protein_targeting
has_narrow_synonym: protein sorting along secretory pathway
has_obo_namespace: biological_process
has_related_synonym: nascent polypeptide association
id: GO:0006605
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that protein targeting encompasses the transport of the protein to the specified location, and may also include additional steps such as protein processing.

Axiom
annotated source: protein targeting
annotated property: definition
annotated target: The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
database_cross_reference: GOC:ma

lipid metabolic process
type: Class
subclass of: biological_process
definition: The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
database_cross_reference: Reactome:REACT_104930
database_cross_reference: Reactome:REACT_107479
database_cross_reference: Reactome:REACT_108775
database_cross_reference: Reactome:REACT_114669
database_cross_reference: Reactome:REACT_115652
database_cross_reference: Reactome:REACT_28745
database_cross_reference: Reactome:REACT_31395
database_cross_reference: Reactome:REACT_32539
database_cross_reference: Reactome:REACT_33836
database_cross_reference: Reactome:REACT_602
database_cross_reference: Reactome:REACT_77176
database_cross_reference: Reactome:REACT_77191
database_cross_reference: Reactome:REACT_79244
database_cross_reference: Reactome:REACT_81778
database_cross_reference: Reactome:REACT_82512
database_cross_reference: Reactome:REACT_82723
database_cross_reference: Reactome:REACT_87884
database_cross_reference: Reactome:REACT_90757
database_cross_reference: Reactome:REACT_94607
database_cross_reference: Reactome:REACT_97906
database_cross_reference: Reactome:REACT_98129
database_cross_reference: Reactome:REACT_99706
database_cross_reference: Wikipedia:Lipid_metabolism
has_exact_synonym: lipid metabolism
has_obo_namespace: biological_process
id: GO:0006629
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: lipid metabolic process
annotated property: definition
annotated target: The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
database_cross_reference: GOC:ma

Lipid digestion, mobilization, and transport, Drosophila melanogaster
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_104930

Lipid digestion, mobilization, and transport, Xenopus tropicalis
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_107479

Lipid digestion, mobilization, and transport, Canis familiaris
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_108775

Lipid digestion, mobilization, and transport, Staphylococcus aureus N315
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_114669

Lipid metabolism, Gallus gallus
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_115652

Lipid digestion, mobilization, and transport, Saccharomyces cerevisiae
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_28745

Lipid digestion, mobilization, and transport, Sus scrofa
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_31395

Lipid digestion, mobilization, and transport, Bos taurus
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_32539

Lipid digestion, mobilization, and transport, Rattus norvegicus
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_33836

Lipid digestion, mobilization, and transport, Homo sapiens
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_602

Lipid digestion, mobilization, and transport, Danio rerio
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_77176

Lipid digestion, mobilization, and transport, Arabidopsis thaliana
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_77191

Lipid digestion, mobilization, and transport, Plasmodium falciparum
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_79244

Lipid digestion, mobilization, and transport, Oryza sativa
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_81778

Lipid digestion, mobilization, and transport, Taeniopygia guttata
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_82512

Lipid digestion, mobilization, and transport, Escherichia coli
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_82723

Lipid digestion, mobilization, and transport, Caenorhabditis elegans
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_87884

Lipid digestion, mobilization, and transport, Mus musculus
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_90757

Lipid digestion, mobilization, and transport, Mycobacterium tuberculosis
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_94607

Lipid digestion, mobilization, and transport, Gallus gallus
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_97906

Lipid digestion, mobilization, and transport, Schizosaccharomyces pombe
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_98129

Lipid digestion, mobilization, and transport, Dictyostelium discoideum
type: Axiom
annotated source: lipid metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_99706

vitamin metabolic process
type: Class
subclass of: biological_process
definition: The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
database_cross_reference: Reactome:REACT_101808
database_cross_reference: Reactome:REACT_101968
database_cross_reference: Reactome:REACT_102472
database_cross_reference: Reactome:REACT_103646
database_cross_reference: Reactome:REACT_104403
database_cross_reference: Reactome:REACT_105907
database_cross_reference: Reactome:REACT_106152
database_cross_reference: Reactome:REACT_108558
database_cross_reference: Reactome:REACT_110948
database_cross_reference: Reactome:REACT_11193
database_cross_reference: Reactome:REACT_13450
database_cross_reference: Reactome:REACT_30091
database_cross_reference: Reactome:REACT_31562
database_cross_reference: Reactome:REACT_33241
database_cross_reference: Reactome:REACT_33738
database_cross_reference: Reactome:REACT_34161
database_cross_reference: Reactome:REACT_34372
database_cross_reference: Reactome:REACT_36524
database_cross_reference: Reactome:REACT_78899
database_cross_reference: Reactome:REACT_79004
database_cross_reference: Reactome:REACT_80415
database_cross_reference: Reactome:REACT_81509
database_cross_reference: Reactome:REACT_82129
database_cross_reference: Reactome:REACT_82903
database_cross_reference: Reactome:REACT_83508
database_cross_reference: Reactome:REACT_84128
database_cross_reference: Reactome:REACT_87513
database_cross_reference: Reactome:REACT_88847
database_cross_reference: Reactome:REACT_88850
database_cross_reference: Reactome:REACT_90099
database_cross_reference: Reactome:REACT_96278
database_cross_reference: Reactome:REACT_96904
database_cross_reference: Reactome:REACT_97734
database_cross_reference: Reactome:REACT_97893
has_exact_synonym: vitamin metabolism
has_obo_namespace: biological_process
id: GO:0006766
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim pir
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: vitamin metabolic process
annotated property: definition
annotated target: The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
database_cross_reference: GOC:ai

Metabolism of vitamins and cofactors, Bos taurus
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_101808

Metabolism of vitamins and cofactors, Saccharomyces cerevisiae
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_101968

Vitamins, Xenopus tropicalis
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_102472

Metabolism of vitamins and cofactors, Staphylococcus aureus N315
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_103646

Vitamins, Bos taurus
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_104403

Metabolism of vitamins and cofactors, Danio rerio
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_105907

Metabolism of vitamins and cofactors, Xenopus tropicalis
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_106152

Metabolism of vitamins and cofactors, Rattus norvegicus
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_108558

Metabolism of vitamins and cofactors, Sus scrofa
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_110948

Metabolism of vitamins and cofactors, Homo sapiens
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_11193

Vitamins, Homo sapiens
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_13450

Metabolism of vitamins and cofactors, Oryza sativa
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_30091

Vitamins, Sus scrofa
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_31562

Vitamins, Oryza sativa
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_33241

Metabolism of vitamins and cofactors, Mycobacterium tuberculosis
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_33738

Metabolism of vitamins and cofactors, Mus musculus
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_34161

Vitamins, Taeniopygia guttata
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_34372

Vitamins, Gallus gallus
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_36524

Metabolism of vitamins and cofactors, Caenorhabditis elegans
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_78899

Vitamins, Danio rerio
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_79004

Vitamins, Rattus norvegicus
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_80415

Metabolism of vitamins and cofactors, Gallus gallus
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_81509

Metabolism of vitamins and cofactors, Taeniopygia guttata
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_82129

Vitamins, Canis familiaris
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_82903

Metabolism of vitamins and cofactors, Arabidopsis thaliana
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_83508

Vitamins, Drosophila melanogaster
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_84128

Metabolism of vitamins and cofactors, Schizosaccharomyces pombe
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_87513

Vitamins, Mus musculus
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_88847

Metabolism of vitamins and cofactors, Dictyostelium discoideum
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_88850

Vitamins, Arabidopsis thaliana
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_90099

Metabolism of vitamins and cofactors, Plasmodium falciparum
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_96278

Metabolism of vitamins and cofactors, Drosophila melanogaster
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_96904

Metabolism of vitamins and cofactors, Escherichia coli
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_97734

Metabolism of vitamins and cofactors, Canis familiaris
type: Axiom
annotated source: vitamin metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_97893

ion transport
type: Class
subclass of: biological_process
definition: The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
database_cross_reference: Reactome:REACT_102356
database_cross_reference: Reactome:REACT_102895
database_cross_reference: Reactome:REACT_106972
database_cross_reference: Reactome:REACT_109067
database_cross_reference: Reactome:REACT_110862
database_cross_reference: Reactome:REACT_19397
database_cross_reference: Reactome:REACT_29110
database_cross_reference: Reactome:REACT_31978
database_cross_reference: Reactome:REACT_33992
database_cross_reference: Reactome:REACT_34201
database_cross_reference: Reactome:REACT_79109
database_cross_reference: Reactome:REACT_82618
database_cross_reference: Reactome:REACT_87822
database_cross_reference: Reactome:REACT_91472
database_cross_reference: Reactome:REACT_91958
database_cross_reference: Reactome:REACT_92903
database_cross_reference: Reactome:REACT_93485
database_cross_reference: Reactome:REACT_94357
database_cross_reference: Reactome:REACT_96078
database_cross_reference: Reactome:REACT_96919
database_cross_reference: Reactome:REACT_98077
has_obo_namespace: biological_process
id: GO:0006811
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: ion transport
annotated property: definition
annotated target: The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
database_cross_reference: GOC:ai

Transport of inorganic cations/anions and amino acids/oligopeptides, Xenopus tropicalis
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_102356

Transport of inorganic cations/anions and amino acids/oligopeptides, Staphylococcus aureus N315
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_102895

Transport of inorganic cations/anions and amino acids/oligopeptides, Sus scrofa
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_106972

Transport of inorganic cations/anions and amino acids/oligopeptides, Saccharomyces cerevisiae
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_109067

Transport of inorganic cations/anions and amino acids/oligopeptides, Arabidopsis thaliana
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_110862

Transport of inorganic cations/anions and amino acids/oligopeptides, Homo sapiens
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_19397

Transport of inorganic cations/anions and amino acids/oligopeptides, Oryza sativa
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_29110

Transport of inorganic cations/anions and amino acids/oligopeptides, Mus musculus
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_31978

Transport of inorganic cations/anions and amino acids/oligopeptides, Danio rerio
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_33992

Transport of inorganic cations/anions and amino acids/oligopeptides, Gallus gallus
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_34201

Transport of inorganic cations/anions and amino acids/oligopeptides, Caenorhabditis elegans
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_79109

Transport of inorganic cations/anions and amino acids/oligopeptides, Escherichia coli
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_82618

Transport of inorganic cations/anions and amino acids/oligopeptides, Bos taurus
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_87822

Transport of inorganic cations/anions and amino acids/oligopeptides, Dictyostelium discoideum
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_91472

Transport of inorganic cations/anions and amino acids/oligopeptides, Drosophila melanogaster
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_91958

Transport of inorganic cations/anions and amino acids/oligopeptides, Mycobacterium tuberculosis
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_92903

Transport of inorganic cations/anions and amino acids/oligopeptides, Canis familiaris
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_93485

Transport of inorganic cations/anions and amino acids/oligopeptides, Rattus norvegicus
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_94357

Transport of inorganic cations/anions and amino acids/oligopeptides, Plasmodium falciparum
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_96078

Transport of inorganic cations/anions and amino acids/oligopeptides, Taeniopygia guttata
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_96919

Transport of inorganic cations/anions and amino acids/oligopeptides, Schizosaccharomyces pombe
type: Axiom
annotated source: ion transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_98077

amino acid transport
type: Class
subclass of: ion transport
definition: The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
has_alternative_id: GO:0006866
database_cross_reference: Reactome:REACT_104605
database_cross_reference: Reactome:REACT_105142
database_cross_reference: Reactome:REACT_105179
database_cross_reference: Reactome:REACT_106669
database_cross_reference: Reactome:REACT_107151
database_cross_reference: Reactome:REACT_107366
database_cross_reference: Reactome:REACT_107449
database_cross_reference: Reactome:REACT_112073
database_cross_reference: Reactome:REACT_115423
database_cross_reference: Reactome:REACT_13796
database_cross_reference: Reactome:REACT_29020
database_cross_reference: Reactome:REACT_81602
database_cross_reference: Reactome:REACT_81848
database_cross_reference: Reactome:REACT_83425
database_cross_reference: Reactome:REACT_90553
database_cross_reference: Reactome:REACT_95755
database_cross_reference: Reactome:REACT_96944
database_cross_reference: Reactome:REACT_98408
database_cross_reference: Reactome:REACT_99072
has_obo_namespace: biological_process
id: GO:0006865
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: amino acid transport
annotated property: definition
annotated target: The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
database_cross_reference: GOC:ai

Amino acid transport across the plasma membrane, Rattus norvegicus
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_104605

Amino acid transport across the plasma membrane, Mus musculus
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_105142

Amino acid transport across the plasma membrane, Caenorhabditis elegans
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_105179

Amino acid transport across the plasma membrane, Dictyostelium discoideum
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_106669

Amino acid transport across the plasma membrane, Arabidopsis thaliana
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_107151

Amino acid transport across the plasma membrane, Gallus gallus
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_107366

Amino acid transport across the plasma membrane, Escherichia coli
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_107449

Amino acid transport across the plasma membrane, Mycobacterium tuberculosis
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_112073

Amino acid transport across the plasma membrane, Saccharomyces cerevisiae
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_115423

Amino acid transport across the plasma membrane, Homo sapiens
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_13796

Amino acid transport across the plasma membrane, Staphylococcus aureus N315
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_29020

Amino acid transport across the plasma membrane, Oryza sativa
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_81602

Amino acid transport across the plasma membrane, Danio rerio
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_81848

Amino acid transport across the plasma membrane, Bos taurus
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_83425

Amino acid transport across the plasma membrane, Drosophila melanogaster
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_90553

Amino acid transport across the plasma membrane, Taeniopygia guttata
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_95755

Amino acid transport across the plasma membrane, Sus scrofa
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_96944

Amino acid transport across the plasma membrane, Xenopus tropicalis
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_98408

Amino acid transport across the plasma membrane, Canis familiaris
type: Axiom
annotated source: amino acid transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_99072

lipid transport
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
has_obo_namespace: biological_process
id: GO:0006869
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: lipid transport
annotated property: definition
annotated target: The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
database_cross_reference: ISBN:0198506732

cellular ion homeostasis
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: occurs in
  some values from: cellular_component
definition: Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
has_obo_namespace: biological_process
id: GO:0006873
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cellular ion homeostasis
annotated property: definition
annotated target: Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
database_cross_reference: GOC:mah

exocytosis
type: Class
subclass of: biological_process
definition: A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. Steps that prepare vesicles for fusion with the membrane (e.g. docking and priming) are included in this process. This is the process in which most molecules are secreted from eukaryotic cells.
has_alternative_id: GO:0016194
has_alternative_id: GO:0016195
database_cross_reference: Wikipedia:Exocytosis
has_exact_synonym: vesicle exocytosis
has_obo_namespace: biological_process
has_related_synonym: nonselective vesicle exocytosis
id: GO:0006887
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: exocytosis
annotated property: definition
annotated target: A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. Steps that prepare vesicles for fusion with the membrane (e.g. docking and priming) are included in this process. This is the process in which most molecules are secreted from eukaryotic cells.
database_cross_reference: GOC:mah
database_cross_reference: ISBN:0716731363

endocytosis
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: has_part
  some values from: membrane invagination
subclass of: Restriction
  on property: has_part
  some values from: vesicle organization
definition: A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
has_alternative_id: GO:0016193
has_alternative_id: GO:0016196
database_cross_reference: Wikipedia:Endocytosis
has_exact_synonym: plasma membrane invagination
has_exact_synonym: vesicle endocytosis
has_obo_namespace: biological_process
has_related_synonym: nonselective vesicle endocytosis
id: GO:0006897
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: endocytosis
annotated property: definition
annotated target: A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
database_cross_reference: GOC:mah
database_cross_reference: ISBN:0198506732
database_cross_reference: ISBN:0716731363

response to osmotic stress
type: Class
subclass of: biological_process
definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
has_exact_synonym: osmotic response
has_exact_synonym: osmotic stress response
has_obo_namespace: biological_process
id: GO:0006970
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: response to osmotic stress
annotated property: definition
annotated target: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
database_cross_reference: GOC:jl

cellular response to DNA damage stimulus
type: Class
subclass of: biological_process
definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
has_alternative_id: GO:0034984
has_broad_synonym: response to DNA damage stimulus
has_exact_synonym: DNA damage response
has_exact_synonym: cellular DNA damage response
has_exact_synonym: response to genotoxic stress
has_obo_namespace: biological_process
id: GO:0006974
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cellular response to DNA damage stimulus
annotated property: definition
annotated target: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
database_cross_reference: GOC:go_curators

response to oxidative stress
type: Class
subclass of: biological_process
definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
has_obo_namespace: biological_process
id: GO:0006979
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: response to oxidative stress
annotated property: definition
annotated target: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
database_cross_reference: GOC:jl
database_cross_reference: PMID:12115731

nucleus organization
type: Class
subclass of: biological_process
definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
has_alternative_id: GO:0048287
has_exact_synonym: nuclear organisation
has_exact_synonym: nuclear organization
has_obo_namespace: biological_process
has_related_synonym: nuclear morphology
has_related_synonym: nuclear organization and biogenesis
has_related_synonym: nucleus organization and biogenesis
id: GO:0006997
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim pir
in_subset: goslim yeast

Axiom
annotated source: nucleus organization
annotated property: definition
annotated target: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
database_cross_reference: GOC:dph
database_cross_reference: GOC:ems
database_cross_reference: GOC:jl
database_cross_reference: GOC:mah

Axiom
annotated source: nucleus organization
annotated property: has_exact_synonym
annotated target: nuclear organisation
database_cross_reference: GOC:curators

Axiom
annotated source: nucleus organization
annotated property: has_exact_synonym
annotated target: nuclear organization
database_cross_reference: GOC:curators

Axiom
annotated source: nucleus organization
annotated property: has_related_synonym
annotated target: nuclear organization and biogenesis
database_cross_reference: GOC:mah

Axiom
annotated source: nucleus organization
annotated property: has_related_synonym
annotated target: nucleus organization and biogenesis
database_cross_reference: GOC:mah

mitochondrion organization
type: Class
subclass of: biological_process
definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
has_exact_synonym: mitochondria organization
has_exact_synonym: mitochondrion organisation
has_obo_namespace: biological_process
has_related_synonym: mitochondrion organization and biogenesis
id: GO:0007005
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim pombe
in_subset: goslim yeast

Axiom
annotated source: mitochondrion organization
annotated property: definition
annotated target: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
database_cross_reference: GOC:dph
database_cross_reference: GOC:jl
database_cross_reference: GOC:mah
database_cross_reference: GOC:sgd_curators
database_cross_reference: PMID:9786946

Axiom
annotated source: mitochondrion organization
annotated property: has_exact_synonym
annotated target: mitochondria organization
database_cross_reference: GOC:mah

Axiom
annotated source: mitochondrion organization
annotated property: has_exact_synonym
annotated target: mitochondrion organisation
database_cross_reference: GOC:mah

Axiom
annotated source: mitochondrion organization
annotated property: has_related_synonym
annotated target: mitochondrion organization and biogenesis
database_cross_reference: GOC:curators

cytoskeleton organization
type: Class
subclass of: biological_process
definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
has_exact_synonym: cytoskeleton organisation
has_obo_namespace: biological_process
has_related_synonym: cytoskeletal organization and biogenesis
has_related_synonym: cytoskeletal regulator activity
has_related_synonym: cytoskeleton organization and biogenesis
id: GO:0007010
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cytoskeleton organization
annotated property: definition
annotated target: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
database_cross_reference: GOC:dph
database_cross_reference: GOC:jl
database_cross_reference: GOC:mah

Axiom
annotated source: cytoskeleton organization
annotated property: has_exact_synonym
annotated target: cytoskeleton organisation
database_cross_reference: GOC:curators

Axiom
annotated source: cytoskeleton organization
annotated property: has_related_synonym
annotated target: cytoskeletal organization and biogenesis
database_cross_reference: GOC:mah

Axiom
annotated source: cytoskeleton organization
annotated property: has_related_synonym
annotated target: cytoskeleton organization and biogenesis
database_cross_reference: GOC:mah

peroxisome organization
type: Class
subclass of: biological_process
definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
has_exact_synonym: peroxisome organisation
has_obo_namespace: biological_process
has_related_synonym: peroxisome organization and biogenesis
has_related_synonym: peroxisome-assembly ATPase activity
id: GO:0007031
in_subset: goslim pir
in_subset: goslim pombe
in_subset: goslim yeast

Axiom
annotated source: peroxisome organization
annotated property: definition
annotated target: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
database_cross_reference: GOC:mah

Axiom
annotated source: peroxisome organization
annotated property: has_exact_synonym
annotated target: peroxisome organisation
database_cross_reference: GOC:curators

Axiom
annotated source: peroxisome organization
annotated property: has_related_synonym
annotated target: peroxisome organization and biogenesis
database_cross_reference: GOC:mah

vacuole organization
type: Class
subclass of: biological_process
definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
has_alternative_id: GO:0044086
has_exact_synonym: vacuole organisation
has_narrow_synonym: vacuolar assembly
has_obo_namespace: biological_process
has_related_synonym: vacuole biogenesis
has_related_synonym: vacuole organization and biogenesis
id: GO:0007033
in_subset: goslim pir
in_subset: goslim yeast

Axiom
annotated source: vacuole organization
annotated property: definition
annotated target: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
database_cross_reference: GOC:mah

Axiom
annotated source: vacuole organization
annotated property: has_exact_synonym
annotated target: vacuole organisation
database_cross_reference: GOC:curators

Axiom
annotated source: vacuole organization
annotated property: has_narrow_synonym
annotated target: vacuolar assembly
database_cross_reference: GOC:mah

Axiom
annotated source: vacuole organization
annotated property: has_related_synonym
annotated target: vacuole biogenesis
database_cross_reference: GOC:mah

Axiom
annotated source: vacuole organization
annotated property: has_related_synonym
annotated target: vacuole organization and biogenesis
database_cross_reference: GOC:mah

chromosome segregation
type: Class
subclass of: biological_process
definition: The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
database_cross_reference: Wikipedia:Chromosome_segregation
has_exact_synonym: chromosome division
has_obo_namespace: biological_process
has_related_synonym: chromosome transmission
id: GO:0007059
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: chromosome segregation
annotated property: definition
annotated target: The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
database_cross_reference: GOC:jl
database_cross_reference: GOC:mah
database_cross_reference: GOC:mtg_cell_cycle
database_cross_reference: GOC:vw

cell budding
type: Class
subclass of: biological_process
definition: A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.
has_broad_synonym: budding
has_obo_namespace: biological_process
id: GO:0007114
in_subset: goslim candida
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cell budding
annotated property: definition
annotated target: A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.
database_cross_reference: ISBN:0198506732

pseudohyphal growth
type: Class
subclass of: biological_process
definition: A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate.
has_obo_namespace: biological_process
id: GO:0007124
in_subset: goslim candida
in_subset: goslim yeast

Axiom
annotated source: pseudohyphal growth
annotated property: definition
annotated target: A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate.
database_cross_reference: GOC:krc
database_cross_reference: PMID:11104818

tRNA processing
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
has_exact_synonym: tRNA maturation
has_obo_namespace: biological_process
id: GO:0008033
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: tRNA processing
annotated property: definition
annotated target: The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
database_cross_reference: GOC:jl
database_cross_reference: PMID:12533506

Axiom
annotated source: tRNA processing
annotated property: has_exact_synonym
annotated target: tRNA maturation
database_cross_reference: GOC:vw

cytoskeletal protein binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
has_obo_namespace: molecular_function
id: GO:0008092
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cytoskeletal protein binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
database_cross_reference: GOC:mah

transcription factor binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
has_exact_synonym: TF binding
has_obo_namespace: molecular_function
id: GO:0008134
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: transcription factor binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
database_cross_reference: ISBN:0198506732

translation factor activity, RNA binding
type: Class
subclass of: RNA binding
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome.
has_broad_synonym: translation factor activity, nucleic acid binding
has_obo_namespace: molecular_function
id: GO:0008135
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: translation factor activity, RNA binding
annotated property: definition
annotated target: Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome.
database_cross_reference: GOC:ai
database_cross_reference: GOC:vw

Axiom
annotated source: translation factor activity, RNA binding
annotated property: has_broad_synonym
annotated target: translation factor activity, nucleic acid binding
database_cross_reference: GOC:mah

biological_process
type: Class
definition: Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
has_alternative_id: GO:0000004
has_alternative_id: GO:0007582
database_cross_reference: Wikipedia:Biological_process
has_exact_synonym: biological process
has_exact_synonym: physiological process
has_obo_namespace: biological_process
id: GO:0008150
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. Note that when this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this.

Axiom
annotated source: biological_process
annotated property: definition
annotated target: Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
database_cross_reference: GOC:go_curators
database_cross_reference: GOC:isa_complete

methyltransferase activity
type: Class
subclass of: transferase activity
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Catalysis of the transfer of a methyl group to an acceptor molecule.
has_alternative_id: GO:0004480
has_broad_synonym: methylase
database_cross_reference: EC:2.1.1
database_cross_reference: Reactome:REACT_100745
database_cross_reference: Reactome:REACT_100863
database_cross_reference: Reactome:REACT_100884
database_cross_reference: Reactome:REACT_103958
database_cross_reference: Reactome:REACT_104757
database_cross_reference: Reactome:REACT_105478
database_cross_reference: Reactome:REACT_105909
database_cross_reference: Reactome:REACT_106465
database_cross_reference: Reactome:REACT_107676
database_cross_reference: Reactome:REACT_15531
database_cross_reference: Reactome:REACT_15553
database_cross_reference: Reactome:REACT_2094
database_cross_reference: Reactome:REACT_29020
database_cross_reference: Reactome:REACT_29098
database_cross_reference: Reactome:REACT_33644
database_cross_reference: Reactome:REACT_33779
database_cross_reference: Reactome:REACT_73401
database_cross_reference: Reactome:REACT_77286
database_cross_reference: Reactome:REACT_78774
database_cross_reference: Reactome:REACT_79799
database_cross_reference: Reactome:REACT_83214
database_cross_reference: Reactome:REACT_84525
database_cross_reference: Reactome:REACT_84974
database_cross_reference: Reactome:REACT_86817
database_cross_reference: Reactome:REACT_86905
database_cross_reference: Reactome:REACT_87169
database_cross_reference: Reactome:REACT_93379
database_cross_reference: Reactome:REACT_93809
database_cross_reference: Reactome:REACT_94274
database_cross_reference: Reactome:REACT_96444
database_cross_reference: Reactome:REACT_99316
has_obo_namespace: molecular_function
id: GO:0008168
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: methyltransferase activity
annotated property: definition
annotated target: Catalysis of the transfer of a methyl group to an acceptor molecule.
database_cross_reference: ISBN:0198506732

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Bos taurus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100745

methylation of Dopamine to form 3-Methoxytyramine, Taeniopygia guttata
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100863

methylation of Dopamine to form 3-Methoxytyramine, Xenopus tropicalis
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100884

methylation of Dopamine to form 3-Methoxytyramine, Rattus norvegicus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103958

guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine, Danio rerio
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104757

guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine, Bos taurus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105478

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Xenopus tropicalis
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105909

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Sus scrofa
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106465

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Schizosaccharomyces pombe
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107676

methylation of Dopamine to form 3-Methoxytyramine, Homo sapiens
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15531

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Homo sapiens
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15553

guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine, Homo sapiens
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_2094

methylation of Dopamine to form 3-Methoxytyramine, Bos taurus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29020

guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine, Canis familiaris
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29098

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Mycobacterium tuberculosis
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33644

methylation of Dopamine to form 3-Methoxytyramine, Mycobacterium tuberculosis
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33779

guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine, Rattus norvegicus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_73401

methylation of Dopamine to form 3-Methoxytyramine, Canis familiaris
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77286

guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine, Mus musculus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78774

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Mus musculus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79799

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Gallus gallus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83214

guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine, Taeniopygia guttata
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84525

methylation of Dopamine to form 3-Methoxytyramine, Sus scrofa
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84974

methylation of Dopamine to form 3-Methoxytyramine, Schizosaccharomyces pombe
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86817

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Rattus norvegicus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86905

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Taeniopygia guttata
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87169

methylation of Dopamine to form 3-Methoxytyramine, Gallus gallus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93379

guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine, Xenopus tropicalis
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93809

Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Canis familiaris
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94274

methylation of Dopamine to form 3-Methoxytyramine, Mus musculus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96444

guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine, Gallus gallus
type: Axiom
annotated source: methyltransferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99316

protein alkylation
type: Class
subclass of: biological_process
definition: The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom.
has_exact_synonym: protein amino acid alkylation
has_obo_namespace: biological_process
id: GO:0008213
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: protein alkylation
annotated property: definition
annotated target: The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom.
database_cross_reference: GOC:ma

Axiom
annotated source: protein alkylation
annotated property: has_exact_synonym
annotated target: protein amino acid alkylation
database_cross_reference: GOC:bf

peptidase activity
type: Class
subclass of: hydrolase activity
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
database_cross_reference: EC:3.4
database_cross_reference: Reactome:REACT_106748
database_cross_reference: Reactome:REACT_110349
database_cross_reference: Reactome:REACT_13710
database_cross_reference: Reactome:REACT_19284
database_cross_reference: Reactome:REACT_93020
database_cross_reference: Reactome:REACT_99630
has_exact_synonym: hydrolase, acting on peptide bonds
has_exact_synonym: peptide hydrolase activity
has_narrow_synonym: protease activity
has_narrow_synonym: proteinase activity
has_obo_namespace: molecular_function
id: GO:0008233
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: peptidase activity
annotated property: definition
annotated target: Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
database_cross_reference: GOC:jl
database_cross_reference: ISBN:0815332181

gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6, Rattus norvegicus
type: Axiom
annotated source: peptidase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106748

gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6, Mus musculus
type: Axiom
annotated source: peptidase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110349

gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6, Homo sapiens
type: Axiom
annotated source: peptidase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_13710

Proteolytic processing of Slit, Homo sapiens
type: Axiom
annotated source: peptidase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19284

gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6, Bos taurus
type: Axiom
annotated source: peptidase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93020

gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6, Gallus gallus
type: Axiom
annotated source: peptidase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99630

lipid binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with a lipid.
has_obo_namespace: molecular_function
id: GO:0008289
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: lipid binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with a lipid.
database_cross_reference: GOC:ai

RNA splicing
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
has_alternative_id: GO:0006395
database_cross_reference: Reactome:REACT_107090
database_cross_reference: Reactome:REACT_107348
database_cross_reference: Reactome:REACT_107931
database_cross_reference: Reactome:REACT_108122
database_cross_reference: Reactome:REACT_113880
database_cross_reference: Reactome:REACT_1735
database_cross_reference: Reactome:REACT_34200
database_cross_reference: Reactome:REACT_81581
database_cross_reference: Reactome:REACT_82520
database_cross_reference: Reactome:REACT_91201
database_cross_reference: Reactome:REACT_94469
database_cross_reference: Reactome:REACT_96521
database_cross_reference: Reactome:REACT_97651
database_cross_reference: Reactome:REACT_98240
database_cross_reference: Reactome:REACT_98753
database_cross_reference: Reactome:REACT_98879
database_cross_reference: Wikipedia:RNA_splicing
has_obo_namespace: biological_process
has_related_synonym: pre-mRNA splicing factor activity
id: GO:0008380
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: RNA splicing
annotated property: definition
annotated target: The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
database_cross_reference: GOC:krc
database_cross_reference: GOC:mah

mRNA Splicing, Gallus gallus
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_107090

mRNA Splicing, Dictyostelium discoideum
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_107348

mRNA Splicing, Caenorhabditis elegans
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_107931

mRNA Splicing, Schizosaccharomyces pombe
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_108122

mRNA Splicing, Taeniopygia guttata
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_113880

mRNA Splicing, Homo sapiens
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_1735

mRNA Splicing, Plasmodium falciparum
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_34200

mRNA Splicing, Oryza sativa
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_81581

mRNA Splicing, Rattus norvegicus
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_82520

mRNA Splicing, Canis familiaris
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_91201

mRNA Splicing, Drosophila melanogaster
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_94469

mRNA Splicing, Bos taurus
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_96521

mRNA Splicing, Xenopus tropicalis
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_97651

mRNA Splicing, Danio rerio
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_98240

mRNA Splicing, Mus musculus
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_98753

mRNA Splicing, Arabidopsis thaliana
type: Axiom
annotated source: RNA splicing
annotated property: database_cross_reference
annotated target: Reactome:REACT_98879

protein transporter activity
type: Class
subclass of: molecular_function
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Enables the directed movement of proteins into, out of or within a cell, or between cells.
has_alternative_id: GO:0015463
has_exact_synonym: protein carrier activity
has_narrow_synonym: enzyme transporter activity
has_narrow_synonym: protein transport chaperone
has_obo_namespace: molecular_function
has_related_synonym: holin
has_related_synonym: secretin
id: GO:0008565
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: protein transporter activity
annotated property: definition
annotated target: Enables the directed movement of proteins into, out of or within a cell, or between cells.
database_cross_reference: ISBN:0198506732

Axiom
annotated source: protein transporter activity
annotated property: has_narrow_synonym
annotated target: protein transport chaperone
database_cross_reference: GOC:dph
database_cross_reference: GOC:mah
database_cross_reference: GOC:tb

carbohydrate transport
type: Class
subclass of: biological_process
definition: The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.
has_alternative_id: GO:0006861
has_alternative_id: GO:0008644
has_narrow_synonym: sugar transport
has_obo_namespace: biological_process
id: GO:0008643
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: carbohydrate transport
annotated property: definition
annotated target: The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.
database_cross_reference: GOC:ai

oligosaccharide metabolic process
type: Class
subclass of: carbohydrate metabolic process
definition: The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
has_exact_synonym: oligosaccharide metabolism
has_obo_namespace: biological_process
id: GO:0009311
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: oligosaccharide metabolic process
annotated property: definition
annotated target: The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
database_cross_reference: ISBN:0198506732

response to heat
type: Class
subclass of: biological_process
definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
has_alternative_id: GO:0006951
has_narrow_synonym: response to heat shock
has_obo_namespace: biological_process
id: GO:0009408
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: response to heat
annotated property: definition
annotated target: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
database_cross_reference: GOC:lr

RNA modification
type: Class
subclass of: biological_process
definition: The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
has_alternative_id: GO:0016547
database_cross_reference: Wikipedia:RNA_editing
has_narrow_synonym: RNA editing
has_obo_namespace: biological_process
id: GO:0009451
in_subset: goslim yeast
in_subset: gosubset prok
comment: The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing.

Axiom
annotated source: RNA modification
annotated property: definition
annotated target: The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
database_cross_reference: GOC:go_curators
database_cross_reference: ISBN:1555811337

Axiom
annotated source: RNA modification
annotated property: has_narrow_synonym
annotated target: RNA editing
database_cross_reference: GOC:hjd

membrane invagination
type: Class
subclass of: biological_process
definition: The infolding of a membrane, resulting in formation of a vesicle.
has_obo_namespace: biological_process
id: GO:0010324
in_subset: goslim yeast

Axiom
annotated source: membrane invagination
annotated property: definition
annotated target: The infolding of a membrane, resulting in formation of a vesicle.
database_cross_reference: GOC:tb

endomembrane system
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: has_part
  some values from: vacuole
subclass of: Restriction
  on property: has_part
  some values from: plasma membrane
definition: A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
database_cross_reference: Wikipedia:Endomembrane_system
has_obo_namespace: cellular_component
id: GO:0012505
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim yeast

Axiom
annotated source: endomembrane system
annotated property: definition
annotated target: A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
database_cross_reference: GOC:lh

nucleobase-containing compound transport
type: Class
subclass of: biological_process
definition: The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
has_obo_namespace: biological_process
has_related_synonym: nucleobase, nucleoside, nucleotide and nucleic acid transport
id: GO:0015931
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: nucleobase-containing compound transport
annotated property: definition
annotated target: The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
database_cross_reference: GOC:ai

Axiom
annotated source: nucleobase-containing compound transport
annotated property: has_related_synonym
annotated target: nucleobase, nucleoside, nucleotide and nucleic acid transport
database_cross_reference: GOC:dph
database_cross_reference: GOC:tb

membrane
type: Class
subclass of: cellular_component
definition: A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
database_cross_reference: Wikipedia:Biological_membrane
has_obo_namespace: cellular_component
id: GO:0016020
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: membrane
annotated property: definition
annotated target: A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
database_cross_reference: GOC:dos
database_cross_reference: GOC:mah
database_cross_reference: ISBN:0815316194

cytoplasmic, membrane-bounded vesicle
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cytoplasm
definition: A membrane-bounded vesicle found in the cytoplasm of the cell.
has_exact_synonym: cytoplasmic membrane bounded vesicle
has_exact_synonym: cytoplasmic membrane-enclosed vesicle
has_obo_namespace: cellular_component
id: GO:0016023
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cytoplasmic, membrane-bounded vesicle
annotated property: definition
annotated target: A membrane-bounded vesicle found in the cytoplasm of the cell.
database_cross_reference: GOC:ai
database_cross_reference: GOC:mah

vesicle organization
type: Class
subclass of: biological_process
definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
has_exact_synonym: vesicle organisation
has_obo_namespace: biological_process
has_related_synonym: vesicle organization and biogenesis
id: GO:0016050
in_subset: goslim pir
in_subset: goslim yeast

Axiom
annotated source: vesicle organization
annotated property: definition
annotated target: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
database_cross_reference: GOC:mah

Axiom
annotated source: vesicle organization
annotated property: has_exact_synonym
annotated target: vesicle organisation
database_cross_reference: GOC:curators

Axiom
annotated source: vesicle organization
annotated property: has_related_synonym
annotated target: vesicle organization and biogenesis
database_cross_reference: GOC:mah

endosomal transport
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
subclass of: Restriction
  on property: occurs in
  some values from: cellular_component
definition: The directed movement of substances into, out of, or mediated by an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.
database_cross_reference: Reactome:REACT_27258
has_obo_namespace: biological_process
has_related_synonym: endosome transport
id: GO:0016197
in_subset: goslim yeast

Axiom
annotated source: endosomal transport
annotated property: definition
annotated target: The directed movement of substances into, out of, or mediated by an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.
database_cross_reference: ISBN:0198506732

Endosomal Sorting Complex Required For Transport (ESCRT), Homo sapiens
type: Axiom
annotated source: endosomal transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_27258

Axiom
annotated source: endosomal transport
annotated property: has_related_synonym
annotated target: endosome transport
database_cross_reference: GOC:bf

kinase activity
type: Class
subclass of: transferase activity
definition: Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
database_cross_reference: Reactome:REACT_100073
database_cross_reference: Reactome:REACT_100078
database_cross_reference: Reactome:REACT_100159
database_cross_reference: Reactome:REACT_100260
database_cross_reference: Reactome:REACT_100298
database_cross_reference: Reactome:REACT_100305
database_cross_reference: Reactome:REACT_100311
database_cross_reference: Reactome:REACT_100390
database_cross_reference: Reactome:REACT_100465
database_cross_reference: Reactome:REACT_100495
database_cross_reference: Reactome:REACT_100519
database_cross_reference: Reactome:REACT_100636
database_cross_reference: Reactome:REACT_100637
database_cross_reference: Reactome:REACT_101024
database_cross_reference: Reactome:REACT_101170
database_cross_reference: Reactome:REACT_101303
database_cross_reference: Reactome:REACT_101431
database_cross_reference: Reactome:REACT_101543
database_cross_reference: Reactome:REACT_101596
database_cross_reference: Reactome:REACT_101638
database_cross_reference: Reactome:REACT_101667
database_cross_reference: Reactome:REACT_101841
database_cross_reference: Reactome:REACT_101862
database_cross_reference: Reactome:REACT_101914
database_cross_reference: Reactome:REACT_102090
database_cross_reference: Reactome:REACT_102093
database_cross_reference: Reactome:REACT_102154
database_cross_reference: Reactome:REACT_102322
database_cross_reference: Reactome:REACT_102330
database_cross_reference: Reactome:REACT_102380
database_cross_reference: Reactome:REACT_102475
database_cross_reference: Reactome:REACT_102499
database_cross_reference: Reactome:REACT_102552
database_cross_reference: Reactome:REACT_102607
database_cross_reference: Reactome:REACT_102711
database_cross_reference: Reactome:REACT_102729
database_cross_reference: Reactome:REACT_102817
database_cross_reference: Reactome:REACT_102887
database_cross_reference: Reactome:REACT_102908
database_cross_reference: Reactome:REACT_102915
database_cross_reference: Reactome:REACT_103060
database_cross_reference: Reactome:REACT_103291
database_cross_reference: Reactome:REACT_103327
database_cross_reference: Reactome:REACT_103359
database_cross_reference: Reactome:REACT_103468
database_cross_reference: Reactome:REACT_103691
database_cross_reference: Reactome:REACT_103727
database_cross_reference: Reactome:REACT_103804
database_cross_reference: Reactome:REACT_103989
database_cross_reference: Reactome:REACT_104022
database_cross_reference: Reactome:REACT_104044
database_cross_reference: Reactome:REACT_104109
database_cross_reference: Reactome:REACT_104209
database_cross_reference: Reactome:REACT_104323
database_cross_reference: Reactome:REACT_104386
database_cross_reference: Reactome:REACT_104523
database_cross_reference: Reactome:REACT_104644
database_cross_reference: Reactome:REACT_104687
database_cross_reference: Reactome:REACT_104730
database_cross_reference: Reactome:REACT_104822
database_cross_reference: Reactome:REACT_104837
database_cross_reference: Reactome:REACT_104878
database_cross_reference: Reactome:REACT_105254
database_cross_reference: Reactome:REACT_105274
database_cross_reference: Reactome:REACT_105345
database_cross_reference: Reactome:REACT_105373
database_cross_reference: Reactome:REACT_105503
database_cross_reference: Reactome:REACT_105561
database_cross_reference: Reactome:REACT_105569
database_cross_reference: Reactome:REACT_105589
database_cross_reference: Reactome:REACT_105664
database_cross_reference: Reactome:REACT_105700
database_cross_reference: Reactome:REACT_105971
database_cross_reference: Reactome:REACT_105976
database_cross_reference: Reactome:REACT_106075
database_cross_reference: Reactome:REACT_106144
database_cross_reference: Reactome:REACT_106159

Axiom
annotated source: kinase activity
annotated property: definition
annotated target: Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
database_cross_reference: ISBN:0198506732

Activation of S6K1, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100073

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100078

Inactivation of Myt1 kinase, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100159

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100260

Phosphorylation of L1 by CK-II, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100298

Regulation of NUDC by phosphorylation, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100305

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100311

Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100390

Phosphorylation and inactivation of eEF2K by activated S6K1, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100465

Cdc6 protein is phosphorylated by CDK, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100495

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100519

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100636

Phosphorylation of the Scc1:Cohesion Complex, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100637

Phosphorylation and inactivation of eEF2K by activated S6K1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101024

Phosphorylation of APC component of the destruction complex, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101170

Activation of the Anaphase Promoting Complex (APC) by PLK1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101303

Mcm2-7 is phosphorylated by DDK, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101431

CAK-mediated phosphorylation of Cyclin E:Cdk2, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101543

Phosphorylation of Cyclin D:Cdk4/6 complexes, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101596

Phosphorylation and activation of CHK2 by ATM, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101638

Down Regulation of Emi1 through Phosphorylation of Emi1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101667

Phosphorylation of Cdc25C at Ser216, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101841

Myt-1 mediated phosphorylation of Cyclin A:Cdc2, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101862

Wee1- mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_101914

Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102090

Phosphorylation and activation of eIF4G by activated S6K1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102093

Autophosphorylation of PAK-2p34 in the activation loop, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102154

RAF1 phosphorylates MEK2, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102322

Phosphorylation of MDM2 at serine-395 by ATM kinase, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102330

Regulation of KIF23 (MKLP1) by phosphorylation, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102380

Inactivation of Myt1 kinase, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102475

CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102499

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102552

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102607

Phosphorylation of L1 by CK-II, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102711

RAF1 phosphorylates MEK1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102729

Phosphorylation of L1 by ERK, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102817

Mcm2-7 is phosphorylated by DDK, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102887

Phosphorylation of the Scc1:Cohesion Complex, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102908

Activation of S6K1, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102915

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains), Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103060

Phosphorylation of complexed TSC2 by PKB, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103291

Phosphorylation of Cyclin E2:Cdk2 complexes by Myt1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103327

Wee1- mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103359

Activation of Cdc25C, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103468

Phosphorylation of COP1 at Ser-387 by ATM, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103691

Phosphorylation of NBS1 by ATM, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103727

Phosphorylation of AKT2 by PDK1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103804

Phosphorylation of NBS1 by ATM, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103989

Phosphorylation of p53 at ser-15 by ATM kinase, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104022

Phosphorylation and activation of Chk1 by ATM, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104044

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104109

Activation of S6K1, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104209

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104323

Phosphorylation and activation of eIF4B by activated S6K1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104386

Inactivation of Wee1 kinase, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104523

Regulation of KIF20A (MKL2) by phosphorylation, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104644

Phosphorylation of L1 by CK-II, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104687

Activation of the Anaphase Promoting Complex (APC) by PLK1, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104730

Phosphorylation of COP1 at Ser-387 by ATM, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104822

SOS phosphorylation and dissociation (SHC), Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104837

Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104878

Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105254

Regulation of KIF20A (MKL2) by phosphorylation, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105274

Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105345

Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105373

Phosphorylation of L1 by ERK, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105503

Phosphorylation of complexed TSC2 by PKB, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105561

CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105569

Phosphorylation of p53 at ser-15 by ATM kinase, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105589

Akt1 phosphorylates BAD protein, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105664

Phosphorylation of PDE3B, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105700

Phosphorylation of Cyclin A:Cdk2 at Tyr 15, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105971

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105976

Akt1 phosphorylates BAD protein, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106075

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106144

Wee1- mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106159

Phosphorylation of TSC2 by PKB, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106186

Activation of the Anaphase Promoting Complex (APC) by PLK1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106225

Phosphorylation of Wee1 kinase by Chk1, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1063

Activation of Cdc25C, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106324

Phosphorylation of L1 by ERK, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106383

Phosphorylation and inactivation of eEF2K by activated S6K1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106411

Regulation of KIF23 (MKLP1) by phosphorylation, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106420

Phosphorylation of Cdc25A at Ser-123 by Chk2, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106500

Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106505

Phosphorylation of NBS1 by ATM, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106514

CAK-mediated phosphorylation of Cyclin E:Cdk2, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106567

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106599

Phosphorylation of Cyclin A:Cdk2 at Tyr 15, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106681

CAK-mediated phosphorylation of Cyclin E:Cdk2, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106722

SOS phosphorylation and dissociation (IRS, Crk), Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106738

CAK-mediated phosphorylation of Cyclin E:Cdk2, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106897

Phosphorylation of Ribosomal protein S6 by activated S6K1, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107009

Phosphorylation of Cdc25C at Ser216, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107055

SOS phosphorylation and dissociation (IRS, Crk), Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107102

Phosphorylation of APC component of the destruction complex, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107243

Phosphorylation of TSC2 by PKB, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107247

CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107310

Inactivation of Myt1 kinase, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107424

Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107623

Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107685

Phosphorylation of the Emi1 DSGxxS degron by Plk1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107732

Phosphorylation of Cdc25C at Ser216, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107736

Phosphorylation and activation of CHK2 by ATM, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107787

Phosphorylation of DLC2 by MAPK-8, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107849

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107854

Plk1-mediated phosphorylation of Nlp, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108002

Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108096

Phosphorylation of Ribosomal protein S6 by activated S6K1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108132

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108362

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108394

Phosphorylation and activation of Chk1 by ATM, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108520

Inactivation of Myt1 kinase, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108578

Free APC/C phosphorylated by Plk1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108776

Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108840

Free APC/C phosphorylated by Plk1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108871

Phosphorylation of Cyclin B1 in the CRS domain, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108971

Phosphorylation of cPLA2 by ERK-2, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108985

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109045

Phosphorylation of Cdc25A at Ser-123 by Chk2, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109065

Phosphorylation of 4E-BP1 by activated mTORC1, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109117

SOS phosphorylation and dissociation (IRS), Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109197

Inactivation of Myt1 kinase, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109244

Free APC/C phosphorylated by Plk1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109260

SOS phosphorylation and dissociation (IRS), Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109264

Activation of the Anaphase Promoting Complex (APC) by PLK1, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109331

Phosphorylation of APC component of the destruction complex, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109367

Regulation of KIF20A (MKL2) by phosphorylation, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109549

CAK-mediated phosphorylation of Cyclin A:Cdk2, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109641

Free APC/C phosphorylated by Plk1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109769

Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109799

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains), Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110175

Phosphorylation of APC component of the destruction complex, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110254

Phosphorylation and activation of Chk1 by ATM, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110296

Phosphorylation and inactivation of eEF2K by activated S6K1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110351

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains), Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110382

Down Regulation of Emi1 through Phosphorylation of Emi1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110530

Phosphorylation of DLC2 by MAPK-8, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110583

Mcm2-7 is phosphorylated by DDK, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110643

Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110679

Inactivation of Myt1 kinase, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110774

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110775

Regulation of KIF23 (MKLP1) by phosphorylation, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110947

Phosphorylation and activation of eIF4G by activated S6K1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110995

FGFR associated PI3K phosphorylates PIP2 to PIP3, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_111124

FGFR-associated PI3K phosphorylates PIP2 to PIP3, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_111171

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1116

Phosphorylation of Cdc25A at Ser-123 by Chk2, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_111930

Regulation of KIF20A (MKL2) by phosphorylation, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1120

Mcm2-7 is phosphorylated by DDK, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112075

Phosphorylation of L1 by CK-II, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112101

Phosphorylation of AKT2 by PDK1, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112156

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112214

Akt1 phosphorylates BAD protein, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112270

Autophosphorylation of DNA-PKcs, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112298

Phosphorylation and activation of eIF4G by activated S6K1, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112324

Regulation of KIF23 (MKLP1) by phosphorylation, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112360

Phosphorylation of Cdc25A at Ser-123 by Chk2, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112413

Inactivation of Wee1 kinase, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112480

Phosphorylation and activation of eIF4G by activated S6K1, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112545

CAK-mediated phosphorylation of Cyclin E:Cdk2, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112633

Phosphorylation of L1 by ERK, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112709

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112722

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112790

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112846

Phosphorylation of BRCA1 at multiple sites by ATM, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112892

Autophosphorylation of DNA-PKcs, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_112948

Phosphorylation of Cyclin B1 in the CRS domain, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113022

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113051

Phosphorylation and activation of eIF4B by activated S6K1, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113121

Phosphorylation of Ribosomal protein S6 by activated S6K1, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113227

CAK-mediated phosphorylation of Cyclin E:Cdk2, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113244

Activation of S6K1, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113269

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113435

Autophosphorylation of DNA-PKcs, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113527

Activation of Cdc25C, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113569

Phosphorylation of Ribosomal protein S6 by activated S6K1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113811

Phosphorylation of Cyclin B1 in the CRS domain, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113820

PIP2 conversion to PIP3, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113894

Phosphorylation of Cdc25A at Ser-123 by Chk1, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113929

Activation of Cdc25C, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113990

CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114160

Phosphorylation of the Scc1:Cohesion Complex, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114198

Phosphorylation of Cdc25A at Ser-123 by Chk1, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114207

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114227

Autophosphorylation of DNA-PKcs, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114233

Autophosphorylation of DNA-PKcs, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114255

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114268

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114280

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114319

Activation of Cdc25C, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114323

Phosphorylation of DLC1 by MAPK 8, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114395

Autophosphorylation of DNA-PKcs, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114434

Phosphorylation of AKT2 by PDK1, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114461

Phosphorylation of BRCA1 at multiple sites by ATM, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114522

Phosphorylation of Cdc25A at Ser-123 by Chk1, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114553

Phosphorylation of TSC2 by PKB, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114599

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114624

Phosphorylation of Ribosomal protein S6 by activated S6K1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114771

Phosphorylation and activation of eIF4G by activated S6K1, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114906

Autophosphorylation of DNA-PKcs, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114984

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115006

Phosphorylation and activation of eIF4G by activated S6K1, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115135

Autophosphorylation of DNA-PKcs, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115168

Autophosphorylation of DNA-PKcs, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115199

Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115358

CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115384

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115440

Phosphorylation of the SA2 Cohesin Complex, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115472

CAK-mediated phosphorylation of Cyclin E:Cdk2, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115475

Autophosphorylation of DNA-PKcs, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115521

Phosphorylation of Cdc25A at Ser-123 by Chk2, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115527

Phosphorylation of H2AX at S139 by ATM at the site of DSB, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115747

Phosphorylation of RAD51 by tyrosine kinase Abelson family protein members, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_116149

Phosphorylation of the Scc1:Cohesion Complex, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_118137

Phosphorylation of the SA2 Cohesin Complex, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_118229

Phosphorylation of the Scc1:Cohesion Complex, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_118284

Phosphorylation of the SA2 Cohesin Complex, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_118307

Phosphorylation of the Scc1:Cohesion Complex, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_118367

Phosphorylation of the SA2 Cohesin Complex, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_118462

Phosphorylation (Ser5) of RNA pol II CTD, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1185

Cdc6 protein is phosphorylated by CDK, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1279

Phosphorylation of Cdc25C at Ser216, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_128

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_132

Regulation of NUDC by phosphorylation, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1326

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_13431

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Oryctolagus cuniculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_13581

Phosphorylation of the Scc1:Cohesion Complex, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1362

Autophosphorylation of PAK-2p34, Oryctolagus cuniculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_13817

Phosphorylation of PDE3B by AKT-1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1382

Autophosphorylation of PAK-2p34 in the activation loop, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_13820

SOS phosphorylation and dissociation (SHC), Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1420

Phosphorylation of the SA2 Cohesin Complex, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1481

Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1517

Plk1-mediated phosphorylation of Nlp, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15386

Phosphorylation and activation of CHK2 by ATM, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1603

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1657

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1680

SOS phosphorylation and dissociation (IRS), Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_169

RAF1 phosphorylates MEK2, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1727

Phosphorylation of p53 at ser-15 by ATM kinase, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1756

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains), Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1782

Activation of the Anaphase Promoting Complex (APC) by PLK1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1808

Phosphorylation of PDE3B, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1878

Akt1 phosphorylates BAD protein, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_188

Phosphorylation of DLC1 by MAPK 8, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1888

Regulation of KIF23 (MKLP1) by phosphorylation, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1930

Phosphorylation of PD-1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19312

Inactivation of Wee1 kinase, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1944

Phosphorylation of DLC2 by MAPK-8, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_1981

Phosphorylation of NBS1 by ATM, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_2009

Raf1 phosphorylates MEK1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_203

Phosphorylation of CREB by ribosomal protein S6 kinase, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20503

Phosphorylation of COP1 at Ser-387 by ATM, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20543

Phosphorylation by MAPK/ERK, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20562

Raf activation, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20578

Phosphorylation of CREB by PKA, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20583

Activation of MAPK, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20631

Phophorylation by PDK1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_20640

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_2066

Orc1 is phosphorylated by cyclin A/CDK2, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_2111

Activation of Cdc25C, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_2119

Autophosphorylation of DNA-PKcs, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_215

Phosphorylation of L1 by ERK, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_22099

Phosphorylation of L1 by CK-II, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_22378

Raf1 phosphorylates MEK2, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_23976

Phosphorylation of cPLA2 by ERK-2, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_23990

PIP2 conversion to PIP3, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_244

SOS phosphorylation and dissociation (IRS, Crk), Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_26

Phosphorylation of Wee1 kinase by Chk1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_264

Phosphorylation of BRCA1 at multiple sites by ATM, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28054

Inactivation of Wee1 kinase, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28091

RAF1 phosphorylates MEK1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28113

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains), Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28163

Phosphorylation of Wee1 kinase by Chk1, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28264

Phosphorylation of Ribosomal protein S6 by activated S6K1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28480

Activation of the Anaphase Promoting Complex (APC) by PLK1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28555

Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28681

Phosphorylation and activation of eIF4B by activated S6K1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28719

RAF1 phosphorylates MEK2, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28743

Phosphorylation of MDM2 at serine-395 by ATM kinase, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28746

Down Regulation of Emi1 through Phosphorylation of Emi1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_28824

Phosphorylation of L1 by ERK, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29029

Phosphorylation of Cyclin A:Cdk2 at Tyr 15, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29168

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29201

Activation of Cdc25C, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29213

CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29277

Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29284

Activation of S6K1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29289

Phosphorylation of L1 by ERK, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29300

Phosphorylation of Ribosomal protein S6 by activated S6K1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29334

Phosphorylation of AKT2 by PDK1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29395

Orc1 is phosphorylated by cyclin A/CDK2, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29396

Regulation of KIF20A (MKL2) by phosphorylation, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29410

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29451

Phosphorylation of 4E-BP1 by activated mTORC1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29588

Regulation of NUDC by phosphorylation, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29614

Cdc6 protein is phosphorylated by CDK, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29689

Phosphorylation of PDE3B, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29694

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29759

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29788

Phosphorylation of APC component of the destruction complex, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29873

Down Regulation of Emi1 through Phosphorylation of Emi1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29914

Phosphorylation (Ser5) of RNA pol II CTD, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30020

Phosphorylation (Ser5) of RNA pol II CTD, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30023

Phosphorylation of BRCA1 at multiple sites by ATM, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30052

Phosphorylation of L1 by CK-II, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30070

PIP2 conversion to PIP3, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30084

SOS phosphorylation and dissociation (IRS, Crk), Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30113

Phosphorylation and activation of eIF4B by activated S6K1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30116

Phosphorylation of the Emi1 DSGxxS degron by Plk1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30165

Phosphorylation and activation of Chk1 by ATM, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_302

Phosphorylation of the SA2 Cohesin Complex, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30230

RAF1 phosphorylates MEK1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30345

Inactivation of Myt1 kinase, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30490

Phosphorylation of the Scc1:Cohesion Complex, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30496

Phosphorylation and inactivation of eEF2K by activated S6K1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30679

Phosphorylation of BRCA1 at multiple sites by ATM, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30700

Inactivation of Myt1 kinase, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30836

Phosphorylation and activation of Chk1 by ATM, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30921

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30938

PIP2 conversion to PIP3, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30948

Plk1-mediated phosphorylation of Nlp, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30985

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30997

Phosphorylation of TSC2 by PKB, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31081

Phosphorylation of the Scc1:Cohesion Complex, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31149

Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31196

Regulation of KIF20A (MKL2) by phosphorylation, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31227

Phosphorylation of the Scc1:Cohesion Complex, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31273

Orc1 is phosphorylated by cyclin A/CDK2, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31290

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31293

Phosphorylation and activation of CHK2 by ATM, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31449

Activation of S6K1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31466

Phosphorylation of the SA2 Cohesin Complex, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31519

Phosphorylation of NBS1 by ATM, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31536

Autophosphorylation of PAK-2p34 in the activation loop, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31571

Phosphorylation of L1 by ERK, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31625

SOS phosphorylation and dissociation (SHC), Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31639

Phosphorylation and activation of CHK2 by ATM, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31868

Phosphorylation of L1 by CK-II, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31915

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31935

Phosphorylation (Ser5) of RNA pol II CTD, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31984

Wee1- mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32009

Inactivation of Myt1 kinase, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32077

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains), Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32079

Phosphorylation of COP1 at Ser-387 by ATM, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32145

Phosphorylation of NBS1 by ATM, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32150

Phosphorylation of cPLA2 by ERK-2, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32271

Phosphorylation of MDM2 at serine-395 by ATM kinase, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32358

Mcm2-7 is phosphorylated by DDK, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32374

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32438

Phosphorylation of BRCA1 at multiple sites by ATM, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32492

Phosphorylation of NBS1 by ATM, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32565

Phosphorylation and activation of eIF4B by activated S6K1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32598

Phosphorylation of the Emi1 DSGxxS degron by Plk1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32620

Phosphorylation of Cyclin D:Cdk4/6 complexes, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32845

Phosphorylation and inactivation of eEF2K by activated S6K1, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32906

Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32956

Phosphorylation of the SA2 Cohesin Complex, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33003

Phosphorylation of L1 by ERK, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33009

Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33080

Phosphorylation of NBS1 by ATM, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33369

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33385

Phosphorylation of the Emi1 DSGxxS degron by Plk1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33519

Phosphorylation of complexed TSC2 by PKB, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33532

Phosphorylation of BRCA1 at multiple sites by ATM, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33692

Regulation of KIF23 (MKLP1) by phosphorylation, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33840

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33928

Phosphorylation of the Emi1 DSGxxS degron by Plk1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33979

Phosphorylation of PD-1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34080

Phosphorylation of Cdc25A at Ser-123 by Chk1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34111

Phosphorylation of cPLA2 by ERK-2, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34145

Phosphorylation of L1 by ERK, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34222

Activation of Cdc25C, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34285

Phosphorylation and activation of Chk1 by ATM, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34310

Phosphorylation (Ser5) of RNA pol II CTD, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34403

Phosphorylation and inactivation of eEF2K by activated S6K1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34514

Cdc6 protein is phosphorylated by CDK, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34516

Phosphorylation of 4E-BP1 by activated mTORC1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34607

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains), Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34741

Phosphorylation and inactivation of eEF2K by activated S6K1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34788

Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34804

Phosphorylation of Cyclin E2:Cdk2 complexes by Myt1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_384

Inactivation of Myt1 kinase, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_414

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_41715

Phosphorylation of Cdc25A at Ser-123 by Chk2, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_43

Down Regulation of Emi1 through Phosphorylation of Emi1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_496

Phosphorylation and activation of eIF4G by activated S6K1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_54449

RAF1 phosphorylates MEK1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_545

Phosphorylation and activation of Chk1 by ATM kinase, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_559

PIP2 conversion to PIP3, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_58131

CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6139

Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6170

Wee1- mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6178

Phosphorylation (Ser5) of RNA pol II CTD, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6234

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6297

Phosphorylation of NEFL by the P-TEFb(Cyclin T1:Cdk9) complex, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6311

CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6314

Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex, Human immunodeficiency virus 1
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6316

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6327

Myt-1 mediated phosphorylation of Cyclin A:Cdc2, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6342

Phosphorylation of Cyclin B1 in the CRS domain, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6353

Phosphorylation of TSC2 by PKB, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6725

Phosphorylation and activation of eIF4B by activated S6K1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6778

Free APC/C phosphorylated by Plk1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6859

Phosphorylation of the Emi1 DSGxxS degron by Plk1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6861

Phosphorylation and activation of eIF4G by activated S6K1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6870

Phosphorylation of 4E-BP1 by activated mTORC1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6873

Phosphorylation and inactivation of eEF2K by activated S6K1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6883

Phosphorylation of Ribosomal protein S6 by activated S6K1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6912

Activation of S6K1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6948

Phosphorylation of complexed TSC2 by PKB, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_6952

Phosphorylation of Cyclin D:Cdk4/6 complexes, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_76979

Phosphorylation of COP1 at Ser-387 by ATM, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77040

Phosphorylation of MDM2 at serine-395 by ATM kinase, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77074

Phosphorylation of Cdc25A at Ser-123 by Chk2, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77179

Phosphorylation of DLC2 by MAPK-8, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77231

Plk1-mediated phosphorylation of Nlp, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77234

Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_773

RAF1 phosphorylates MEK2, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77326

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77362

Phosphorylation of the Emi1 DSGxxS degron by Plk1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77365

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77397

Regulation of NUDC by phosphorylation, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77407

Activation of the Anaphase Promoting Complex (APC) by PLK1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77443

Phosphorylation of L1 by CK-II, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77450

Phosphorylation of Cyclin D:Cdk4/6 complexes, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77535

CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77550

CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77566

Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77606

Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77615

CAK-mediated phosphorylation of Cyclin A:Cdk2, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77654

Regulation of KIF23 (MKLP1) by phosphorylation, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77660

Phosphorylation of PDE3B, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77733

Activation of the Anaphase Promoting Complex (APC) by PLK1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77834

Phosphorylation (Ser5) of RNA pol II CTD, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77857

Phosphorylation of Wee1 kinase by Chk1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77897

Mcm2-7 is phosphorylated by DDK, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77911

Autophosphorylation of PAK-2p34 in the activation loop, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77928

Phosphorylation of Wee1 kinase by Chk1, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77949

Phosphorylation of Cyclin B1 in the CRS domain, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77977

Plk1-mediated phosphorylation of Nlp, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78014

Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78035

Phosphorylation of TSC2 by PKB, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78087

Phosphorylation of Cdc25A at Ser-123 by Chk2, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78121

Regulation of NUDC by phosphorylation, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78226

Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78281

Myt-1 mediated phosphorylation of Cyclin A:Cdc2, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78427

Phosphorylation and activation of eIF4B by activated S6K1, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78450

CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78451

Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78503

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78533

Down Regulation of Emi1 through Phosphorylation of Emi1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78539

Free APC/C phosphorylated by Plk1, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78556

Phosphorylation and inactivation of eEF2K by activated S6K1, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78625

CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78651

Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78696

Cdc6 protein is phosphorylated by CDK, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78748

Phosphorylation (Ser5) of RNA pol II CTD, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78901

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79012

Autophosphorylation of PAK-2p34 in the activation loop, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79039

Phosphorylation of Wee1 kinase by Chk1, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79087

SOS phosphorylation and dissociation (IRS), Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79125

Phosphorylation of Cyclin B1 in the CRS domain, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79182

Mcm2-7 is phosphorylated by DDK, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79208

Phosphorylation of 4E-BP1 by activated mTORC1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79220

Phosphorylation of p53 at ser-15 by ATM kinase, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79255

Cdc6 protein is phosphorylated by CDK, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79372

Phosphorylation of p53 at ser-15 by ATM kinase, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79573

Phosphorylation of the Scc1:Cohesion Complex, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79686

Autophosphorylation of PAK-2p34 in the activation loop, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79694

Activation of S6K1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79700

Orc1 is phosphorylated by cyclin A/CDK2, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79709

Phosphorylation of Cyclin E2:Cdk2 complexes by Myt1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79720

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80110

Phosphorylation of complexed TSC2 by PKB, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80144

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80185

Activation of S6K1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80213

Phosphorylation of the Scc1:Cohesion Complex, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80218

Regulation of KIF20A (MKL2) by phosphorylation, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80239

Mcm2-7 is phosphorylated by DDK, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80255

Regulation of KIF20A (MKL2) by phosphorylation, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80591

Phosphorylation of NBS1 by ATM, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80606

Inactivation of Wee1 kinase, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80617

Phosphorylation of L1 by ERK, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80632

Down Regulation of Emi1 through Phosphorylation of Emi1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80665

Phosphorylation of COP1 at Ser-387 by ATM, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80684

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80689

PIP2 conversion to PIP3, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80699

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80700

CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80714

Phosphorylation of PDE3B, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80804

Phosphorylation (Ser5) of RNA pol II CTD, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80853

Phosphorylation of MDM2 at serine-395 by ATM kinase, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80860

Phosphorylation of Cdc25A at Ser-123 by Chk1, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_80909

PIP2 conversion to PIP3, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81027

Phosphorylation and activation of CHK2 by ATM, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81148

Phosphorylation and activation of CHK2 by ATM, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81218

Phosphorylation of APC component of the destruction complex, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81439

Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81458

Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81490

Wee1- mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81590

Phosphorylation of Cyclin E2:Cdk2 complexes by Myt1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81616

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81647

Phosphorylation of Cdc25A at Ser-123 by Chk1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81652

Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81693

Orc1 is phosphorylated by cyclin A/CDK2, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81715

Phosphorylation of Cyclin A:Cdk2 at Tyr 15, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81727

Phosphorylation of Cx43 by c-src, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81864

Phosphorylation of Cdc25A at Ser-123 by Chk1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81941

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82037

Phosphorylation and activation of Chk1 by ATM, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82115

Phosphorylation of complexed TSC2 by PKB, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82125

PIP2 conversion to PIP3, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82128

Phosphorylation of DLC2 by MAPK-8, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82261

Autophosphorylation of PAK-2p34 in the activation loop, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82270

Phosphorylation of Cyclin D:Cdk4/6 complexes, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82303

Phosphorylation and activation of Chk1 by ATM, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82310

CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82361

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82456

Phosphorylation of the SA2 Cohesin Complex, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82473

Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82616

Phosphorylation of complexed TSC2 by PKB, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82678

Plk1-mediated phosphorylation of Nlp, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82728

Down Regulation of Emi1 through Phosphorylation of Emi1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82751

Inactivation of Wee1 kinase, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82824

Phosphorylation of DLC2 by MAPK-8, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82901

PIP2 conversion to PIP3, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_82927

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83006

Inactivation of Myt1 kinase, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83089

Phosphorylation (Ser5) of RNA pol II CTD, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83110

Phosphorylation and activation of Chk1 by ATM, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83178

Phosphorylation of the SA2 Cohesin Complex, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83187

Phosphorylation and activation of eIF4G by activated S6K1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83239

Phosphorylation of NBS1 by ATM, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83279

CAK-mediated phosphorylation of Cyclin A:Cdk2, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83297

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83436

Phosphorylation and activation of CHK2 by ATM, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83476

Wee1- mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83529

Phosphorylation and activation of Chk1 by ATM, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83533

Phosphorylation of Wee1 kinase by Chk1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83579

Plk1-mediated phosphorylation of Nlp, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83582

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83671

Free APC/C phosphorylated by Plk1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83696

Phosphorylation of Cdc25A at Ser-123 by Chk1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83709

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83727

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains), Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83899

Phosphorylation of COP1 at Ser-387 by ATM, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83979

Phosphorylation of the SA2 Cohesin Complex, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84080

Phosphorylation of Wee1 kinase by Chk1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84082

CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84208

Phosphorylation of L1 by ERK, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84273

Phosphorylation of COP1 at Ser-387 by ATM, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84348

Phosphorylation of p53 at ser-15 by ATM kinase, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84405

Phosphorylation of Cdc25A at Ser-123 by Chk1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_845

Cdc6 protein is phosphorylated by CDK, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84560

Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84656

Phosphorylation of Wee1 kinase by Chk1, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84932

Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85009

Activation of S6K1, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85017

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85044

Activation of the Anaphase Promoting Complex (APC) by PLK1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85066

Phosphorylation of Cdc25C at Ser216, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85256

Regulation of KIF20A (MKL2) by phosphorylation, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85328

Phosphorylation of Cx43 by c-src, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85379

Phosphorylation and activation of eIF4G by activated S6K1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85449

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85586

Phosphorylation of Cyclin B1 in the CRS domain, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85699

Phosphorylation of L1 by ERK, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85720

CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85745

Phosphorylation of BRCA1 at multiple sites by ATM, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85751

Phosphorylation and activation of Chk1 by ATM, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85812

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85836

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_85871

Phosphorylation of the SA2 Cohesin Complex, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86014

Phosphorylation and activation of CHK2 by ATM, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86033

Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86061

Phosphorylation of COP1 at Ser-387 by ATM, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86092

Activation of the Anaphase Promoting Complex (APC) by PLK1, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86211

Phosphorylation of Cyclin A:Cdk2 at Tyr 15, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86252

Regulation of NUDC by phosphorylation, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86261

Phosphorylation of TSC2 by PKB, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86277

Phosphorylation and activation of eIF4G by activated S6K1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86365

Akt1 phosphorylates BAD protein, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86372

Phosphorylation of Cx43 by c-src, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86415

Phosphorylation of PD-1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86422

Cdc6 protein is phosphorylated by CDK, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86533

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86736

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86800

Phosphorylation of p53 at ser-15 by ATM kinase, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86867

Phosphorylation of Ribosomal protein S6 by activated S6K1, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86952

Phosphorylation (Ser5) of RNA pol II CTD, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86967

Regulation of NUDC by phosphorylation, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87010

Phosphorylation of cPLA2 by ERK-2, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87121

Phosphorylation of L1 by CK-II, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87149

Phosphorylation of Cx43 by c-src, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87212

Cdc6 protein is phosphorylated by CDK, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87222

Phosphorylation of Cyclin A:Cdk2 at Tyr 15, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87298

Regulation of KIF23 (MKLP1) by phosphorylation, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87329

Phosphorylation of Cx43 by c-src, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87391

SOS phosphorylation and dissociation (SHC), Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87424

Phosphorylation of AKT2 by PDK1, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87437

Activation of S6K1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87485

Akt1 phosphorylates BAD protein, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87497

Phosphorylation of Cyclin E2:Cdk2 complexes by Myt1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87503

Phosphorylation of Cyclin B1 in the CRS domain, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87523

Phosphorylation of MDM2 at serine-395 by ATM kinase, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87534

Activation of the Anaphase Promoting Complex (APC) by PLK1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87593

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87650

Phosphorylation of PDE3B, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87679

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87753

CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87880

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87967

Activation of S6K1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88025

Phosphorylation of NBS1 by ATM, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88055

Phosphorylation of Cdc25A at Ser-123 by Chk1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88091

Regulation of KIF23 (MKLP1) by phosphorylation, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88220

Phosphorylation of Cdc25A at Ser-123 by Chk1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88298

CAK-mediated phosphorylation of Cyclin A:Cdk2, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88326

CAK-mediated phosphorylation of Cyclin A:Cdk2, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88374

Phosphorylation and inactivation of eEF2K by activated S6K1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88421

Orc1 is phosphorylated by cyclin A/CDK2, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88430

Phosphorylation of Ribosomal protein S6 by activated S6K1, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88440

Phosphorylation of cPLA2 by ERK-2, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88458

Inactivation of Wee1 kinase, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88486

Cdc6 protein is phosphorylated by CDK, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88516

Phosphorylation of the Emi1 DSGxxS degron by Plk1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88548

Plk1-mediated phosphorylation of Nlp, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88564

Phosphorylation of Cdc25A at Ser-123 by Chk2, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88590

Phosphorylation of Cdc25A at Ser-123 by Chk2, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88665

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88668

Phosphorylation (Ser5) of RNA pol II CTD, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88766

Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88871

Autophosphorylation of PAK-2p34 in the activation loop, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88928

Free APC/C phosphorylated by Plk1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88987

Phosphorylation of Cdc25A at Ser-123 by Chk1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89001

Phosphorylation of PD-1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89026

Activation of Cdc25C, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89122

Phosphorylation of APC component of the destruction complex, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89366

Phosphorylation of AKT2 by PDK1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89427

Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89464

Phosphorylation of NBS1 by ATM, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89547

Phosphorylation of Ribosomal protein S6 by activated S6K1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89579

Phosphorylation of MDM2 at serine-395 by ATM kinase, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89769

Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89794

Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89879

Phosphorylation of Ribosomal protein S6 by activated S6K1, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89988

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9007

Phosphorylation of AKT2 by PDK1, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90132

Phosphorylation of Wee1 kinase by Chk1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90167

Wee1- mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90220

Phosphorylation of AKT2 by PDK1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90227

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90290

Regulation of NUDC by phosphorylation, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90364

Phosphorylation of Wee1 kinase by Chk1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90426

Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90449

Regulation of NUDC by phosphorylation, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90562

Phosphorylation of Cyclin A:Cdk2 at Tyr 15, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9057

CAK-mediated phosphorylation of Cyclin E:Cdk2, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9067

Phosphorylation (Ser5) of RNA pol II CTD, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90675

Mcm2-7 is phosphorylated by DDK, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_907

CAK-mediated phosphorylation of Cyclin A:Cdk2, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9070

Phosphorylation of AKT2 by PDK1, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_908

Phosphorylation of Wee1 kinase by Chk1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90917

SOS phosphorylation and dissociation (IRS, Crk), Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91050

Phosphorylation of Cyclin E2:Cdk2 complexes by Myt1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91062

Inactivation of Wee1 kinase, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91085

Phosphorylation and activation of CHK2 by ATM, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91156

Phosphorylation (Ser5) of RNA pol II CTD, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91157

Phosphorylation of 4E-BP1 by activated mTORC1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91196

Phosphorylation and activation of eIF4B by activated S6K1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91197

Phosphorylation of Cdc25A at Ser-123 by Chk2, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91240

Down Regulation of Emi1 through Phosphorylation of Emi1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91263

SOS phosphorylation and dissociation (IRS), Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91382

Regulation of KIF20A (MKL2) by phosphorylation, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91470

PIP2 conversion to PIP3, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91501

Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91541

Phosphorylation of DLC2 by MAPK-8, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91574

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91643

Phosphorylation of the SA2 Cohesin Complex, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91684

Regulation of KIF23 (MKLP1) by phosphorylation, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91760

Phosphorylation of APC component of the destruction complex, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91937

Inactivation of Myt1 kinase, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92033

Myt-1 mediated phosphorylation of Cyclin A:Cdc2, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92108

Activation of S6K1, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92126

Autophosphorylation of PAK-2p34 in the activation loop, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92148

Phosphorylation of PDE3B, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92219

Phosphorylation of the Emi1 DSGxxS degron by Plk1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92247

Regulation of KIF23 (MKLP1) by phosphorylation, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92407

Autophosphorylation of PAK-2p34 in the activation loop, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92735

Phosphorylation of L1 by ERK, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92736

Phosphorylation of Wee1 kinase by Chk1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92804

SOS phosphorylation and dissociation (SHC), Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92852

Phosphorylation of TSC2 by PKB, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92889

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92915

RAF1 phosphorylates MEK1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92929

Phosphorylation and activation of Chk1 by ATM, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92951

RAF1 phosphorylates MEK1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93018

Phosphorylation of cPLA2 by ERK-2, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93105

CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93124

Phosphorylation of Ribosomal protein S6 by activated S6K1, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93149

Phosphorylation and activation of Chk1 by ATM, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93166

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93219

Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93221

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93346

Phosphorylation of cPLA2 by ERK-2, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93366

Phosphorylation of Ribosomal protein S6 by activated S6K1, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93414

Regulation of KIF20A (MKL2) by phosphorylation, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93440

Regulation of KIF23 (MKLP1) by phosphorylation, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93441

CAK-mediated phosphorylation of Cyclin A:Cdk2, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93613

Phosphorylation of MDM2 at serine-395 by ATM kinase, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93615

Phosphorylation of BRCA1 at multiple sites by ATM, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_937

RAF1 phosphorylates MEK1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93706

Phosphorylation of Cyclin A:Cdk2 at Tyr 15, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93746

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93878

SOS phosphorylation and dissociation (IRS, Crk), Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94017

Phosphorylation of Cx43 by c-src, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94113

Phosphorylation of Wee1 kinase by Chk1, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94151

SOS phosphorylation and dissociation (SHC), Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94248

Phosphorylation of p53 at ser-15 by ATM kinase, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94258

Phosphorylation of Cyclin B1 in the CRS domain, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94298

Orc1 is phosphorylated by cyclin A/CDK2, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94397

Phosphorylation of PD-1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94428

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains), Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94452

Phosphorylation and activation of eIF4B by activated S6K1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94464

Phosphorylation of the Scc1:Cohesion Complex, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94562

SOS phosphorylation and dissociation (IRS, Crk), Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94615

Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94784

Phosphorylation of the SA2 Cohesin Complex, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94817

Autophosphorylation of PAK-2p34 in the activation loop, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94947

Phosphorylation of Ribosomal protein S6 by activated S6K1, Oryza sativa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95052

Phosphorylation of the Scc1:Cohesion Complex, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95087

Inactivation of Wee1 kinase, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95088

Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95089

Regulation of NUDC by phosphorylation, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95155

CAK-mediated phosphorylation of Cyclin A:Cdk2, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95163

Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95437

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95461

Phosphorylation of Cdc25C at Ser216, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95504

PIP2 conversion to PIP3, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95769

Phosphorylation of Cyclin D:Cdk4/6 complexes, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96

Myt-1 mediated phosphorylation of Cyclin A:Cdc2, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96039

Phosphorylation of PDE3B, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96088

SOS phosphorylation and dissociation (IRS), Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96097

Phosphorylation of Cx43 by c-src, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96102

Phosphorylation and activation of eIF4G by activated S6K1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96129

Regulation of NUDC by phosphorylation, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96200

Phosphorylation of COP1 at Ser-387 by ATM, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96208

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96218

Free APC/C phosphorylated by Plk1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96356

Phosphorylation of L1 by CK-II, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96461

Autophosphorylation of PAK-2p34 in the activation loop, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96468

Phosphorylation of COP1 at Ser-387 by ATM, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96483

RAF1 phosphorylates MEK2, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96500

Activation of Cdc25C, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96524

Plk1-mediated phosphorylation of Nlp, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96656

Phosphorylation and activation of CHK2 by ATM, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96666

Phosphorylation of Cdc25A at Ser-123 by Chk2, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96758

Activation of S6K1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96793

CAK-mediated phosphorylation of Cyclin E:Cdk2, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96797

Phosphorylation of MDM2 at serine-395 by ATM kinase, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96877

Phosphorylation of TSC2 by PKB, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96899

Cdc6 protein is phosphorylated by CDK, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_96968

Phosphorylation and activation of eIF4G by activated S6K1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97193

Orc1 is phosphorylated by cyclin A/CDK2, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97218

Activation of S6K1, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97282

Phosphorylation of Cyclin E2:Cdk2 complexes by Myt1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97299

Activation of the Anaphase Promoting Complex (APC) by PLK1, Dictyostelium discoideum
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97458

Myt-1 mediated phosphorylation of Cyclin A:Cdc2, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97577

Mcm2-7 is phosphorylated by DDK, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97661

Phosphorylation of complexed TSC2 by PKB, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97667

Phosphorylation of cPLA2 by ERK-2, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97748

Phosphorylation of Cx43 by c-src, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97759

Phosphorylation of Cdc25A at Ser-123 by Chk2, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97847

Phosphorylation of BRCA1 at multiple sites by ATM, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97905

Myt-1 mediated phosphorylation of Cyclin A:Cdc2, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98024

Phosphorylation of Cdc25C at Ser216, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98050

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98066

Regulation of NUDC by phosphorylation, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98109

Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98176

Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98213

RAF1 phosphorylates MEK2, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98253

Phosphorylation of Cyclin B1 in the CRS domain, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98296

Myt-1 mediated phosphorylation of Cyclin A:Cdc2, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98373

Phosphorylation of COP1 at Ser-387 by ATM, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98378

Phosphorylation and activation of Chk1 by ATM, Arabidopsis thaliana
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98395

Phosphorylation and inactivation of eEF2K by activated S6K1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98434

Phosphorylation of 4E-BP1 by activated mTORC1, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98436

Inactivation of Wee1 kinase, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98443

Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98493

Autophosphorylation of PAK-2p34 in the activation loop, Saccharomyces cerevisiae
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98558

Phosphorylation and activation of CHK2 by ATM, Xenopus tropicalis
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98560

Regulation of KIF23 (MKLP1) by phosphorylation, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98663

Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98708

Phosphorylation of Cdc25A at Ser-123 by Chk1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98731

Phosphorylation of TSC2 by PKB, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98738

Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98741

Phosphorylation of Cx43 by c-src, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98779

Phosphorylation of MDM2 at serine-395 by ATM kinase, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_988

Phosphorylation of complexed TSC2 by PKB, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98847

Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98908

Phosphorylation of PD-1, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98913

Phosphorylation of AKT2 by PDK1, Rattus norvegicus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98971

Free APC/C phosphorylated by Plk1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98996

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99025

CAK-mediated phosphorylation of Cyclin E:Cdk2, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99053

Phosphorylation of NBS1 by ATM, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99141

Inactivation of Wee1 kinase, Drosophila melanogaster
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99158

Phosphorylation of Ribosomal protein S6 by activated S6K1, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99207

Phosphorylation of AKT2 by PDK1, Danio rerio
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99231

Activation of the Anaphase Promoting Complex (APC) by PLK1, Caenorhabditis elegans
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99266

Phosphorylation of Cyclin D:Cdk4/6 complexes, Sus scrofa
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99302

RAF1 phosphorylates MEK1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99311

Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9955

Phosphorylation of Ribosomal protein S6 by activated S6K1, Mus musculus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99556

RAF1 phosphorylates MEK2, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99560

Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9959

Phosphorylation of Cyclin A:Cdk2 at Tyr 15, Bos taurus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99595

Phosphorylation of DLC2 by MAPK-8, Taeniopygia guttata
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99713

Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9978

Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Canis familiaris
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99785

Phosphorylation of APC component of the destruction complex, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9983

Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9987

Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Gallus gallus
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99929

Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Schizosaccharomyces pombe
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99966

Phosphorylation of Cx43 by c-src, Homo sapiens
type: Axiom
annotated source: kinase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_9997

oxidoreductase activity
type: Class
subclass of: molecular_function
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
database_cross_reference: EC:1
database_cross_reference: Reactome:REACT_102858
database_cross_reference: Reactome:REACT_102973
database_cross_reference: Reactome:REACT_103874
database_cross_reference: Reactome:REACT_104604
database_cross_reference: Reactome:REACT_105062
database_cross_reference: Reactome:REACT_105121
database_cross_reference: Reactome:REACT_106088
database_cross_reference: Reactome:REACT_106276
database_cross_reference: Reactome:REACT_107002
database_cross_reference: Reactome:REACT_107467
database_cross_reference: Reactome:REACT_108745
database_cross_reference: Reactome:REACT_109500
database_cross_reference: Reactome:REACT_110582
database_cross_reference: Reactome:REACT_115316
database_cross_reference: Reactome:REACT_15389
database_cross_reference: Reactome:REACT_15410
database_cross_reference: Reactome:REACT_17006
database_cross_reference: Reactome:REACT_17042
database_cross_reference: Reactome:REACT_29212
database_cross_reference: Reactome:REACT_30160
database_cross_reference: Reactome:REACT_31762
database_cross_reference: Reactome:REACT_32960
database_cross_reference: Reactome:REACT_34705
database_cross_reference: Reactome:REACT_44470
database_cross_reference: Reactome:REACT_78923
database_cross_reference: Reactome:REACT_84842
database_cross_reference: Reactome:REACT_86178
database_cross_reference: Reactome:REACT_88304
database_cross_reference: Reactome:REACT_89057
database_cross_reference: Reactome:REACT_90394
database_cross_reference: Reactome:REACT_91638
database_cross_reference: Reactome:REACT_91952
database_cross_reference: Reactome:REACT_92075
database_cross_reference: Reactome:REACT_92434
database_cross_reference: Reactome:REACT_93539
database_cross_reference: Reactome:REACT_93974
database_cross_reference: Reactome:REACT_95169
database_cross_reference: Reactome:REACT_95558
database_cross_reference: Reactome:REACT_95573
database_cross_reference: Reactome:REACT_97234
database_cross_reference: Reactome:REACT_97568
database_cross_reference: Reactome:REACT_97851
database_cross_reference: Reactome:REACT_98022
database_cross_reference: Reactome:REACT_99085
database_cross_reference: Reactome:REACT_99794
database_cross_reference: Reactome:REACT_99989
has_exact_synonym: redox activity
has_narrow_synonym: oxidoreductase activity, acting on other substrates
has_obo_namespace: molecular_function
id: GO:0016491
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that enzymes of class EC:1.97.-.- should also be annotated to this term.

Axiom
annotated source: oxidoreductase activity
annotated property: definition
annotated target: Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
database_cross_reference: GOC:go_curators

Diiodinated tyrosine can be deiodinated, Mus musculus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102858

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Canis familiaris
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_102973

Monoiodinated tyrosine can be deiodinated, Canis familiaris
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_103874

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Danio rerio
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_104604

Monoiodinated tyrosine can be deiodinated, Danio rerio
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105062

Monoiodinated tyrosine can be deiodinated, Caenorhabditis elegans
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_105121

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Rattus norvegicus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106088

Monoiodinated tyrosine can be deiodinated, Rattus norvegicus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106276

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2], Sus scrofa
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107002

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2], Rattus norvegicus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_107467

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Taeniopygia guttata
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108745

Monoiodinated tyrosine can be deiodinated, Bos taurus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_109500

Diiodinated tyrosine can be deiodinated, Rattus norvegicus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110582

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Drosophila melanogaster
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115316

Monoiodinated tyrosine can be deiodinated, Homo sapiens
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15389

Diiodinated tyrosine can be deiodinated, Homo sapiens
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15410

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Homo sapiens
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_17006

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2], Homo sapiens
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_17042

Diiodinated tyrosine can be deiodinated, Canis familiaris
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_29212

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2], Mus musculus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_30160

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Gallus gallus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_31762

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Bos taurus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_32960

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Mus musculus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_34705

Monoiodinated tyrosine can be deiodinated, Mus musculus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_44470

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2], Taeniopygia guttata
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_78923

Diiodinated tyrosine can be deiodinated, Gallus gallus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84842

Monoiodinated tyrosine can be deiodinated, Xenopus tropicalis
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_86178

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2], Bos taurus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88304

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2], Gallus gallus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89057

Diiodinated tyrosine can be deiodinated, Xenopus tropicalis
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90394

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Arabidopsis thaliana
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91638

Monoiodinated tyrosine can be deiodinated, Gallus gallus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91952

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Xenopus tropicalis
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92075

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2], Canis familiaris
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_92434

Diiodinated tyrosine can be deiodinated, Drosophila melanogaster
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93539

Diiodinated tyrosine can be deiodinated, Taeniopygia guttata
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_93974

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2], Danio rerio
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95169

Monoiodinated tyrosine can be deiodinated, Sus scrofa
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95558

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Caenorhabditis elegans
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_95573

Diiodinated tyrosine can be deiodinated, Caenorhabditis elegans
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97234

Diiodinated tyrosine can be deiodinated, Sus scrofa
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97568

Diiodinated tyrosine can be deiodinated, Bos taurus
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_97851

Monoiodinated tyrosine can be deiodinated, Drosophila melanogaster
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98022

palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Oryza sativa
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99085

Diiodinated tyrosine can be deiodinated, Danio rerio
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99794

Monoiodinated tyrosine can be deiodinated, Taeniopygia guttata
type: Axiom
annotated source: oxidoreductase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_99989

histone modification
type: Class
subclass of: chromatin organization
definition: The covalent alteration of one or more amino acid residues within a histone protein.
database_cross_reference: Wikipedia:Histone#Histone_modifications_in_chromatin_regulation
has_obo_namespace: biological_process
id: GO:0016570
in_subset: goslim yeast

Axiom
annotated source: histone modification
annotated property: definition
annotated target: The covalent alteration of one or more amino acid residues within a histone protein.
database_cross_reference: GOC:krc

transferase activity
type: Class
subclass of: molecular_function
definition: Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
database_cross_reference: EC:2
database_cross_reference: Reactome:REACT_25050
has_obo_namespace: molecular_function
id: GO:0016740
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: transferase activity
annotated property: definition
annotated target: Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
database_cross_reference: ISBN:0198506732

Molybdenum ion transfer onto molybdopterin, Homo sapiens
type: Axiom
annotated source: transferase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_25050

transferase activity, transferring glycosyl groups
type: Class
subclass of: transferase activity
definition: Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
has_alternative_id: GO:0016932
database_cross_reference: EC:2.4
has_exact_synonym: glycosyltransferase activity
has_exact_synonym: transglycosidase activity
has_exact_synonym: transglycosylase activity
has_narrow_synonym: transferase activity, transferring other glycosyl groups
has_obo_namespace: molecular_function
id: GO:0016757
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that enzymes of class EC:2.4.99.- should also be annotated to this term.

Axiom
annotated source: transferase activity, transferring glycosyl groups
annotated property: definition
annotated target: Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
database_cross_reference: GOC:jl
database_cross_reference: ISBN:0198506732

nucleotidyltransferase activity
type: Class
subclass of: transferase activity
definition: Catalysis of the transfer of a nucleotidyl group to a reactant.
database_cross_reference: EC:2.7.7
has_obo_namespace: molecular_function
id: GO:0016779
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: nucleotidyltransferase activity
annotated property: definition
annotated target: Catalysis of the transfer of a nucleotidyl group to a reactant.
database_cross_reference: ISBN:0198506732

hydrolase activity
type: Class
subclass of: molecular_function
definition: Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
database_cross_reference: EC:3
database_cross_reference: Reactome:REACT_110436
database_cross_reference: Reactome:REACT_111159
database_cross_reference: Reactome:REACT_15331
database_cross_reference: Reactome:REACT_83734
database_cross_reference: Reactome:REACT_84047
database_cross_reference: Reactome:REACT_87959
database_cross_reference: Reactome:REACT_88159
database_cross_reference: Reactome:REACT_90118
database_cross_reference: Reactome:REACT_91045
database_cross_reference: Reactome:REACT_98572
has_obo_namespace: molecular_function
id: GO:0016787
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: hydrolase activity
annotated property: definition
annotated target: Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
database_cross_reference: ISBN:0198506732

Hydrolysis of phosphatidylcholine, Bos taurus
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110436

Partial proteolysis of antigen in phagolysosomes, Homo sapiens
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_111159

Hydrolysis of phosphatidylcholine, Homo sapiens
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_15331

Hydrolysis of phosphatidylcholine, Danio rerio
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_83734

Hydrolysis of phosphatidylcholine, Xenopus tropicalis
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84047

Hydrolysis of phosphatidylcholine, Gallus gallus
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87959

Hydrolysis of phosphatidylcholine, Canis familiaris
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88159

Hydrolysis of phosphatidylcholine, Mus musculus
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_90118

Hydrolysis of phosphatidylcholine, Taeniopygia guttata
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91045

Hydrolysis of phosphatidylcholine, Rattus norvegicus
type: Axiom
annotated source: hydrolase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_98572

phosphatase activity
type: Class
subclass of: hydrolase activity
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
has_alternative_id: GO:0003869
has_alternative_id: GO:0016302
database_cross_reference: EC:3.1.3
database_cross_reference: EC:3.1.3.41
database_cross_reference: MetaCyc:4-NITROPHENYLPHOSPHATASE-RXN
database_cross_reference: RHEA:21667
has_exact_synonym: phosphoric monoester hydrolase activity
has_narrow_synonym: 4-nitrophenylphosphatase activity
has_narrow_synonym: 4-nitrophenylphosphate phosphohydrolase activity
has_narrow_synonym: K-pNPPase activity
has_narrow_synonym: NPPase activity
has_narrow_synonym: PNPPase activity
has_narrow_synonym: ecto-p-nitrophenyl phosphatase activity
has_narrow_synonym: nitrophenyl phosphatase activity
has_narrow_synonym: p-nitrophenylphosphatase activity
has_narrow_synonym: p-nitrophenylphosphate phosphohydrolase activity
has_narrow_synonym: para-nitrophenyl phosphatase activity
has_obo_namespace: molecular_function
has_related_synonym: phosphatase
id: GO:0016791
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: phosphatase activity
annotated property: definition
annotated target: Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
database_cross_reference: EC:3.1.3
database_cross_reference: EC:3.1.3.41
database_cross_reference: GOC:curators
database_cross_reference: GOC:pg

Axiom
annotated source: phosphatase activity
annotated property: has_narrow_synonym
annotated target: 4-nitrophenylphosphate phosphohydrolase activity
database_cross_reference: EC:3.1.3.41

Axiom
annotated source: phosphatase activity
annotated property: has_narrow_synonym
annotated target: K-pNPPase activity
database_cross_reference: EC:3.1.3.41

Axiom
annotated source: phosphatase activity
annotated property: has_narrow_synonym
annotated target: NPPase activity
database_cross_reference: EC:3.1.3.41

Axiom
annotated source: phosphatase activity
annotated property: has_narrow_synonym
annotated target: PNPPase activity
database_cross_reference: EC:3.1.3.41

Axiom
annotated source: phosphatase activity
annotated property: has_narrow_synonym
annotated target: ecto-p-nitrophenyl phosphatase activity
database_cross_reference: EC:3.1.3.41

Axiom
annotated source: phosphatase activity
annotated property: has_narrow_synonym
annotated target: nitrophenyl phosphatase activity
database_cross_reference: EC:3.1.3.41

Axiom
annotated source: phosphatase activity
annotated property: has_narrow_synonym
annotated target: p-nitrophenylphosphatase activity
database_cross_reference: EC:3.1.3.41

Axiom
annotated source: phosphatase activity
annotated property: has_narrow_synonym
annotated target: p-nitrophenylphosphate phosphohydrolase activity
database_cross_reference: EC:3.1.3.41

Axiom
annotated source: phosphatase activity
annotated property: has_narrow_synonym
annotated target: para-nitrophenyl phosphatase activity
database_cross_reference: EC:3.1.3.41

hydrolase activity, acting on glycosyl bonds
type: Class
subclass of: hydrolase activity
definition: Catalysis of the hydrolysis of any glycosyl bond.
database_cross_reference: EC:3.2
has_exact_synonym: glycosidase activity
has_narrow_synonym: N-glycosylase
has_narrow_synonym: glycosylase
has_obo_namespace: molecular_function
id: GO:0016798
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: hydrolase activity, acting on glycosyl bonds
annotated property: definition
annotated target: Catalysis of the hydrolysis of any glycosyl bond.
database_cross_reference: GOC:jl

lyase activity
type: Class
subclass of: molecular_function
definition: Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
database_cross_reference: EC:4
has_narrow_synonym: other lyase activity
has_obo_namespace: molecular_function
id: GO:0016829
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that enzymes of class EC:4.99.-.- should also be annotated to this term.

Axiom
annotated source: lyase activity
annotated property: definition
annotated target: Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
database_cross_reference: EC:4.-.-.-
database_cross_reference: ISBN:0198547684

isomerase activity
type: Class
subclass of: molecular_function
definition: Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
database_cross_reference: EC:5
has_narrow_synonym: other isomerase activity
has_obo_namespace: molecular_function
id: GO:0016853
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that enzymes of class EC:5.99.-.- should also be annotated to this term.

Axiom
annotated source: isomerase activity
annotated property: definition
annotated target: Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
database_cross_reference: ISBN:0198506732

ligase activity
type: Class
subclass of: molecular_function
definition: Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
database_cross_reference: EC:6
database_cross_reference: Reactome:REACT_115603
database_cross_reference: Reactome:REACT_116018
has_exact_synonym: synthetase activity
has_obo_namespace: molecular_function
id: GO:0016874
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: ligase activity
annotated property: definition
annotated target: Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
database_cross_reference: EC:6
database_cross_reference: GOC:mah

Ligation of DNA at sites of patch replacement, Gallus gallus
type: Axiom
annotated source: ligase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_115603

Ligation of newly synthesized repair patch to incised DNA in GG-NER, Gallus gallus
type: Axiom
annotated source: ligase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_116018

Axiom
annotated source: ligase activity
annotated property: has_exact_synonym
annotated target: synthetase activity
database_cross_reference: GOC:jh2

ATPase activity
type: Class
subclass of: hydrolase activity
definition: Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
has_alternative_id: GO:0004002
database_cross_reference: EC:3.6.1.3
database_cross_reference: MetaCyc:ADENOSINETRIPHOSPHATASE-RXN
database_cross_reference: RHEA:13068
database_cross_reference: Reactome:REACT_100141
database_cross_reference: Reactome:REACT_108873
database_cross_reference: Reactome:REACT_110992
database_cross_reference: Reactome:REACT_113271
database_cross_reference: Reactome:REACT_18320
database_cross_reference: Reactome:REACT_27184
database_cross_reference: Reactome:REACT_33329
database_cross_reference: Reactome:REACT_79964
database_cross_reference: Reactome:REACT_84196
database_cross_reference: Reactome:REACT_87020
database_cross_reference: Reactome:REACT_89934
has_exact_synonym: ATP hydrolase activity
has_exact_synonym: ATP monophosphatase activity
has_exact_synonym: ATP phosphohydrolase activity
has_exact_synonym: adenosine 5'-triphosphatase activity
has_exact_synonym: adenosine triphosphatase activity
has_exact_synonym: adenosinetriphosphatase activity
has_narrow_synonym: (Ca2+ + Mg2+)-ATPase
has_narrow_synonym: HCO3--ATPase
has_obo_namespace: molecular_function
has_related_synonym: SV40 T-antigen
has_related_synonym: complex V (mitochondrial electron transport)
id: GO:0016887
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: ATPase activity
annotated property: definition
annotated target: Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
database_cross_reference: EC:3.6.1.3
database_cross_reference: GOC:jl

Trafficking of GluR2-containing AMPA receptors to synapse, Canis familiaris
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100141

Trafficking of GluR2-containing AMPA receptors to synapse, Bos taurus
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_108873

Trafficking of GluR2-containing AMPA receptors to synapse, Danio rerio
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_110992

Trafficking of GluR2-containing AMPA receptors to synapse, Xenopus tropicalis
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113271

Trafficking of GluR2-containing AMPA receptors to synapse, Homo sapiens
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_18320

ESCRT Disassembly, Homo sapiens
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_27184

Trafficking of GluR2-containing AMPA receptors to synapse, Gallus gallus
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_33329

Trafficking of GluR2-containing AMPA receptors to synapse, Mus musculus
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_79964

Trafficking of GluR2-containing AMPA receptors to synapse, Drosophila melanogaster
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_84196

Trafficking of GluR2-containing AMPA receptors to synapse, Rattus norvegicus
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_87020

Trafficking of GluR2-containing AMPA receptors to synapse, Taeniopygia guttata
type: Axiom
annotated source: ATPase activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_89934

Axiom
annotated source: ATPase activity
annotated property: has_exact_synonym
annotated target: ATP hydrolase activity
database_cross_reference: EC:3.6.1.3

Axiom
annotated source: ATPase activity
annotated property: has_exact_synonym
annotated target: ATP monophosphatase activity
database_cross_reference: EC:3.6.1.3

Axiom
annotated source: ATPase activity
annotated property: has_exact_synonym
annotated target: adenosine 5'-triphosphatase activity
database_cross_reference: EC:3.6.1.3

Axiom
annotated source: ATPase activity
annotated property: has_exact_synonym
annotated target: adenosine triphosphatase activity
database_cross_reference: EC:3.6.1.3

Axiom
annotated source: ATPase activity
annotated property: has_narrow_synonym
annotated target: (Ca2+ + Mg2+)-ATPase
database_cross_reference: EC:3.6.1.3

Axiom
annotated source: ATPase activity
annotated property: has_narrow_synonym
annotated target: HCO3--ATPase
database_cross_reference: EC:3.6.1.3

Axiom
annotated source: ATPase activity
annotated property: has_related_synonym
annotated target: SV40 T-antigen
database_cross_reference: EC:3.6.1.3

Axiom
annotated source: ATPase activity
annotated property: has_related_synonym
annotated target: complex V (mitochondrial electron transport)
database_cross_reference: EC:3.6.1.3

peptidyl-amino acid modification
type: Class
subclass of: biological_process
definition: The alteration of an amino acid residue in a peptide.
has_obo_namespace: biological_process
id: GO:0018193
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: peptidyl-amino acid modification
annotated property: definition
annotated target: The alteration of an amino acid residue in a peptide.
database_cross_reference: GOC:mah

rRNA binding
type: Class
subclass of: RNA binding
definition: Interacting selectively and non-covalently with ribosomal RNA.
has_obo_namespace: molecular_function
id: GO:0019843
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: rRNA binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with ribosomal RNA.
database_cross_reference: GOC:jl

enzyme binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with any enzyme.
has_obo_namespace: molecular_function
id: GO:0019899
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: enzyme binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with any enzyme.
database_cross_reference: GOC:jl

transmembrane transporter activity
type: Class
subclass of: molecular_function
subclass of: Restriction
  on property: part of
  some values from: transmembrane transport
definition: Enables the transfer of a substance from one side of a membrane to the other.
has_alternative_id: GO:0005386
has_alternative_id: GO:0015646
database_cross_reference: Reactome:REACT_100033
database_cross_reference: Reactome:REACT_106735
database_cross_reference: Reactome:REACT_111088
database_cross_reference: Reactome:REACT_111933
database_cross_reference: Reactome:REACT_113047
database_cross_reference: Reactome:REACT_113116
database_cross_reference: Reactome:REACT_113829
database_cross_reference: Reactome:REACT_114161
database_cross_reference: Reactome:REACT_19288
database_cross_reference: Reactome:REACT_77235
database_cross_reference: Reactome:REACT_81225
database_cross_reference: Reactome:REACT_88503
database_cross_reference: Reactome:REACT_91849
database_cross_reference: Reactome:REACT_94185
has_obo_namespace: molecular_function
id: GO:0022857
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: transmembrane transporter activity
annotated property: definition
annotated target: Enables the transfer of a substance from one side of a membrane to the other.
database_cross_reference: GOC:mtg_transport
database_cross_reference: ISBN:0815340729

GLUT9 transports glucose, fructose and urate, Gallus gallus
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_100033

GLUT9 transports glucose, fructose and urate, Xenopus tropicalis
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_106735

Egress of internalized antigen to the cytosol via sec61, Homo sapiens
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_111088

GLUT9 transports glucose, fructose and urate, Plasmodium falciparum
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_111933

GLUT9 transports glucose, fructose and urate, Dictyostelium discoideum
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113047

GLUT9 transports glucose, fructose and urate, Mycobacterium tuberculosis
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113116

GLUT9 transports glucose, fructose and urate, Arabidopsis thaliana
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_113829

GLUT9 transports glucose, fructose and urate, Oryza sativa
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_114161

GLUT9 transports glucose, fructose and urate, Homo sapiens
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_19288

GLUT9 transports glucose, fructose and urate, Canis familiaris
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_77235

GLUT9 transports glucose, fructose and urate, Bos taurus
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_81225

GLUT9 transports glucose, fructose and urate, Taeniopygia guttata
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_88503

GLUT9 transports glucose, fructose and urate, Mus musculus
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_91849

GLUT9 transports glucose, fructose and urate, Rattus norvegicus
type: Axiom
annotated source: transmembrane transporter activity
annotated property: database_cross_reference
annotated target: Reactome:REACT_94185

signaling
type: Class
subclass of: biological_process
definition: The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
creation date: 2010-02-16T09:30:50Z
has_alternative_id: GO:0023046
has_exact_synonym: biological signaling
has_exact_synonym: signaling process
has_exact_synonym: signalling
has_obo_namespace: biological_process
has_related_synonym: signalling process
id: GO:0023052
in_subset: goslim pombe
in_subset: goslim yeast
comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change.

Axiom
annotated source: signaling
annotated property: definition
annotated target: The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
database_cross_reference: GOC:mtg_signal
database_cross_reference: GOC:mtg_signaling_feb11
database_cross_reference: GOC:signaling

Axiom
annotated source: signaling
annotated property: has_related_synonym
annotated target: signalling process
database_cross_reference: GOC:mah

enzyme regulator activity
type: Class
subclass of: molecular_function
subclass of: Restriction
  on property: part of
  some values from: biological_process
subclass of: Restriction
  on property: has_part
  some values from: enzyme binding
subclass of: Restriction
  on property: regulates
  some values from: molecular_function
definition: Binds to and modulates the activity of an enzyme.
has_alternative_id: GO:0010576
has_exact_synonym: catalytic regulator activity
has_exact_synonym: enzyme modulator
has_narrow_synonym: metalloenzyme regulator activity
has_obo_namespace: molecular_function
id: GO:0030234
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim plant
in_subset: goslim yeast
in_subset: gosubset prok
comment: GO:0030234 is reserved for cases when the regulator directly interacts with the enzyme. When regulation of enzyme activity is achieved without enzyme binding, or when the mechanism of regulation is unknown, instead annotate to 'regulation of catalytic activity ; GO:0050790'.

Axiom
annotated source: enzyme regulator activity
annotated property: definition
annotated target: Binds to and modulates the activity of an enzyme.
database_cross_reference: GOC:dph
database_cross_reference: GOC:mah
database_cross_reference: GOC:tb

Axiom
annotated source: enzyme regulator activity
annotated property: has_exact_synonym
annotated target: catalytic regulator activity
database_cross_reference: GOC:dph

site of polarized growth
type: Class
subclass of: cellular_component
subclass of: Restriction
  on property: part of
  some values from: cellular_component
definition: Any part of a cell where non-isotropic growth takes place.
has_alternative_id: GO:0000134
has_alternative_id: GO:0030483
has_obo_namespace: cellular_component
id: GO:0030427
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim pir
in_subset: goslim yeast

Axiom
annotated source: site of polarized growth
annotated property: definition
annotated target: Any part of a cell where non-isotropic growth takes place.
database_cross_reference: GOC:mah

triplet codon-amino acid adaptor activity
type: Class
subclass of: RNA binding
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.
has_obo_namespace: molecular_function
has_related_synonym: tRNA
has_related_synonym: transfer RNA
id: GO:0030533
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
comment: Note that this term can be used in place of the obsolete term 'transfer RNA ; GO:0005563'.

Axiom
annotated source: triplet codon-amino acid adaptor activity
annotated property: definition
annotated target: The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.
database_cross_reference: GOC:hjd
database_cross_reference: GOC:mtg_MIT_16mar07
database_cross_reference: ISBN:0198506732

RNA modification guide activity
type: Class
subclass of: RNA binding
definition: Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.
has_obo_namespace: molecular_function
id: GO:0030555
in_subset: goslim generic
in_subset: goslim yeast
comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.

Axiom
annotated source: RNA modification guide activity
annotated property: definition
annotated target: Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.
database_cross_reference: GOC:mah
database_cross_reference: PMID:12457565

protein binding, bridging
type: Class
subclass of: molecular_function
definition: The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
has_narrow_synonym: protein-protein adaptor
has_obo_namespace: molecular_function
id: GO:0030674
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: protein binding, bridging
annotated property: definition
annotated target: The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
database_cross_reference: GOC:bf
database_cross_reference: GOC:mah
database_cross_reference: GOC:vw

regulation of protein modification process
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: regulates
  some values from: biological_process
definition: Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
has_obo_namespace: biological_process
id: GO:0031399
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: regulation of protein modification process
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
database_cross_reference: GOC:mah
database_cross_reference: GOC:tb

ubiquitin-like protein binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein.
has_exact_synonym: small conjugating protein binding
has_obo_namespace: molecular_function
id: GO:0032182
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast

Axiom
annotated source: ubiquitin-like protein binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein.
database_cross_reference: GOC:mah

Axiom
annotated source: ubiquitin-like protein binding
annotated property: has_exact_synonym
annotated target: small conjugating protein binding
database_cross_reference: GOC:dph

transposition
type: Class
subclass of: biological_process
definition: Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.
database_cross_reference: Wikipedia:Transposon
has_obo_namespace: biological_process
id: GO:0032196
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: transposition
annotated property: definition
annotated target: Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.
database_cross_reference: GOC:jp
database_cross_reference: ISBN:1555812090

telomere organization
type: Class
subclass of: biological_process
definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins.
has_exact_synonym: chromosome organization, telomeric
has_exact_synonym: organization of chromosome, telomeric region
has_exact_synonym: telomere organisation
has_obo_namespace: biological_process
has_related_synonym: telomere organization and biogenesis
id: GO:0032200
in_subset: goslim pombe
in_subset: goslim yeast

Axiom
annotated source: telomere organization
annotated property: definition
annotated target: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins.
database_cross_reference: GOC:dph
database_cross_reference: GOC:jl
database_cross_reference: GOC:mah

Axiom
annotated source: telomere organization
annotated property: has_exact_synonym
annotated target: telomere organisation
database_cross_reference: GOC:mah

Axiom
annotated source: telomere organization
annotated property: has_related_synonym
annotated target: telomere organization and biogenesis
database_cross_reference: GOC:mah

mitochondrial translation
type: Class
subclass of: mitochondrion organization
subclass of: Restriction
  on property: has_part
  some values from: translational elongation
subclass of: Restriction
  on property: occurs in
  some values from: mitochondrion
definition: The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
has_exact_synonym: mitochondrial protein anabolism
has_exact_synonym: mitochondrial protein biosynthesis
has_exact_synonym: mitochondrial protein formation
has_exact_synonym: mitochondrial protein synthesis
has_exact_synonym: mitochondrial protein translation
has_obo_namespace: biological_process
id: GO:0032543
in_subset: goslim yeast

Axiom
annotated source: mitochondrial translation
annotated property: definition
annotated target: The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
database_cross_reference: GOC:go_curators

monocarboxylic acid metabolic process
type: Class
subclass of: biological_process
definition: The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
has_exact_synonym: monocarboxylate metabolic process
has_exact_synonym: monocarboxylic acid metabolism
has_obo_namespace: biological_process
id: GO:0032787
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: monocarboxylic acid metabolic process
annotated property: definition
annotated target: The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
database_cross_reference: GOC:vk

regulation of organelle organization
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: regulates
  some values from: biological_process
definition: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
has_exact_synonym: regulation of organelle organisation
has_obo_namespace: biological_process
has_related_synonym: regulation of organelle organization and biogenesis
id: GO:0033043
in_subset: goslim yeast

Axiom
annotated source: regulation of organelle organization
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
database_cross_reference: GOC:mah

Axiom
annotated source: regulation of organelle organization
annotated property: has_exact_synonym
annotated target: regulation of organelle organisation
database_cross_reference: GOC:mah

Axiom
annotated source: regulation of organelle organization
annotated property: has_related_synonym
annotated target: regulation of organelle organization and biogenesis
database_cross_reference: GOC:mah

response to chemical
type: Class
subclass of: biological_process
definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
has_exact_synonym: response to chemical stimulus
has_exact_synonym: response to chemical substance
has_obo_namespace: biological_process
id: GO:0042221
in_subset: gocheck do not manually annotate
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim yeast
in_subset: gosubset prok
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

Axiom
annotated source: response to chemical
annotated property: definition
annotated target: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
database_cross_reference: GOC:jl

Axiom
annotated source: response to chemical
annotated property: has_exact_synonym
annotated target: response to chemical stimulus
database_cross_reference: GOC:dos

ribosome assembly
type: Class
subclass of: organelle assembly
definition: The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
has_alternative_id: GO:0042257
has_narrow_synonym: ribosomal subunit assembly
has_obo_namespace: biological_process
id: GO:0042255
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: ribosome assembly
annotated property: definition
annotated target: The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
database_cross_reference: GOC:ma

Axiom
annotated source: ribosome assembly
annotated property: has_narrow_synonym
annotated target: ribosomal subunit assembly
database_cross_reference: GOC:mah
database_cross_reference: GOC:vw

ribosomal large subunit biogenesis
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
has_exact_synonym: ribosomal large subunit biogenesis and assembly
has_obo_namespace: biological_process
id: GO:0042273
in_subset: goslim yeast

Axiom
annotated source: ribosomal large subunit biogenesis
annotated property: definition
annotated target: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
database_cross_reference: GOC:jl

ribosomal small subunit biogenesis
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
has_exact_synonym: ribosomal small subunit biogenesis and assembly
has_obo_namespace: biological_process
id: GO:0042274
in_subset: goslim yeast

Axiom
annotated source: ribosomal small subunit biogenesis
annotated property: definition
annotated target: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
database_cross_reference: GOC:jl

histone binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
has_obo_namespace: molecular_function
has_related_synonym: histone-specific chaperone activity
id: GO:0042393
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim yeast

Axiom
annotated source: histone binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
database_cross_reference: GOC:jl

response to starvation
type: Class
subclass of: biological_process
definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
has_obo_namespace: biological_process
id: GO:0042594
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: response to starvation
annotated property: definition
annotated target: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
database_cross_reference: GOC:go_curators

snoRNA processing
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Any process involved in the conversion of a primary small nucleolar RNA (snoRNA) transcript into a mature snoRNA.
has_obo_namespace: biological_process
id: GO:0043144
in_subset: goslim yeast

Axiom
annotated source: snoRNA processing
annotated property: definition
annotated target: Any process involved in the conversion of a primary small nucleolar RNA (snoRNA) transcript into a mature snoRNA.
database_cross_reference: GOC:go_curators
database_cross_reference: PMID:12773397

ion binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.
has_obo_namespace: molecular_function
has_related_synonym: atom binding
id: GO:0043167
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: ion binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.
database_cross_reference: GOC:jl

protein acylation
type: Class
subclass of: biological_process
definition: The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.
has_exact_synonym: protein amino acid acylation
has_obo_namespace: biological_process
id: GO:0043543
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: protein acylation
annotated property: definition
annotated target: The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.
database_cross_reference: GOC:jl

Axiom
annotated source: protein acylation
annotated property: has_exact_synonym
annotated target: protein amino acid acylation
database_cross_reference: GOC:bf

sporulation
type: Class
subclass of: biological_process
definition: The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
database_cross_reference: Wikipedia:Spore
has_obo_namespace: biological_process
id: GO:0043934
in_subset: goslim metagenomics
in_subset: goslim yeast

Axiom
annotated source: sporulation
annotated property: definition
annotated target: The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
database_cross_reference: GOC:pamgo_curators

cellular respiration
type: Class
subclass of: generation of precursor metabolites and energy
definition: The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
has_broad_synonym: respiration
database_cross_reference: Wikipedia:Cellular_respiration
has_exact_synonym: oxidative metabolic process
has_exact_synonym: oxidative metabolism
has_obo_namespace: biological_process
id: GO:0045333
in_subset: goslim aspergillus
in_subset: goslim candida
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cellular respiration
annotated property: definition
annotated target: The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
database_cross_reference: GOC:das
database_cross_reference: ISBN:0140513590
database_cross_reference: ISBN:0198506732

Golgi vesicle transport
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
subclass of: Restriction
  on property: occurs in
  some values from: cellular_component
definition: The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
has_obo_namespace: biological_process
has_related_synonym: Golgi-derived vesicle transport
id: GO:0048193
in_subset: goslim yeast

Axiom
annotated source: Golgi vesicle transport
annotated property: definition
annotated target: The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
database_cross_reference: GOC:jid
database_cross_reference: ISBN:0716731363
database_cross_reference: PMID:10219233

organelle fusion
type: Class
subclass of: biological_process
definition: The creation of a single organelle from two or more organelles.
has_obo_namespace: biological_process
id: GO:0048284
in_subset: goslim pir
in_subset: goslim yeast

Axiom
annotated source: organelle fusion
annotated property: definition
annotated target: The creation of a single organelle from two or more organelles.
database_cross_reference: GOC:jid

organelle fission
type: Class
subclass of: biological_process
definition: The creation of two or more organelles by division of one organelle.
has_obo_namespace: biological_process
id: GO:0048285
in_subset: goslim pir
in_subset: goslim yeast

Axiom
annotated source: organelle fission
annotated property: definition
annotated target: The creation of two or more organelles by division of one organelle.
database_cross_reference: GOC:jid

organelle inheritance
type: Class
subclass of: biological_process
definition: The partitioning of organelles between daughter cells at cell division.
has_obo_namespace: biological_process
id: GO:0048308
in_subset: goslim pir
in_subset: goslim yeast

Axiom
annotated source: organelle inheritance
annotated property: definition
annotated target: The partitioning of organelles between daughter cells at cell division.
database_cross_reference: GOC:jid

regulation of transport
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: regulates
  some values from: biological_process
definition: Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
has_obo_namespace: biological_process
id: GO:0051049
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: regulation of transport
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
database_cross_reference: GOC:ai

regulation of DNA metabolic process
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: regulates
  some values from: biological_process
definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
has_exact_synonym: regulation of DNA metabolism
has_obo_namespace: biological_process
id: GO:0051052
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: regulation of DNA metabolic process
annotated property: definition
annotated target: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
database_cross_reference: GOC:ai

unfolded protein binding
type: Class
subclass of: molecular_function
definition: Interacting selectively and non-covalently with an unfolded protein.
has_narrow_synonym: binding unfolded ER proteins
has_obo_namespace: molecular_function
has_related_synonym: chaperone activity
has_related_synonym: fimbrium-specific chaperone activity
has_related_synonym: glycoprotein-specific chaperone activity
has_related_synonym: histone-specific chaperone activity
has_related_synonym: ribosomal chaperone activity
has_related_synonym: tubulin-specific chaperone activity
id: GO:0051082
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: unfolded protein binding
annotated property: definition
annotated target: Interacting selectively and non-covalently with an unfolded protein.
database_cross_reference: GOC:ai

nuclear transport
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
subclass of: Restriction
  on property: occurs in
  some values from: cellular_component
definition: The directed movement of substances into, out of, or within the nucleus.
database_cross_reference: Reactome:REACT_9004
database_cross_reference: Wikipedia:Nuclear_transport
has_exact_synonym: nucleus transport
has_obo_namespace: biological_process
id: GO:0051169
in_subset: goslim yeast

Axiom
annotated source: nuclear transport
annotated property: definition
annotated target: The directed movement of substances into, out of, or within the nucleus.
database_cross_reference: GOC:ai

Import of PIC to the Host Nucleus, Homo sapiens
type: Axiom
annotated source: nuclear transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_9004

cofactor metabolic process
type: Class
subclass of: biological_process
definition: The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
has_exact_synonym: cofactor metabolism
has_obo_namespace: biological_process
id: GO:0051186
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pir
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cofactor metabolic process
annotated property: definition
annotated target: The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
database_cross_reference: GOC:ai

meiotic cell cycle
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
subclass of: Restriction
  on property: has_part
  some values from: organelle fission
definition: Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
has_broad_synonym: meiosis
database_cross_reference: Wikipedia:Meiosis
has_obo_namespace: biological_process
id: GO:0051321
in_subset: goslim yeast

Axiom
annotated source: meiotic cell cycle
annotated property: definition
annotated target: Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
database_cross_reference: GOC:ai

proteolysis involved in cellular protein catabolic process
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
has_exact_synonym: peptidolysis involved in cellular protein catabolic process
has_exact_synonym: peptidolysis involved in cellular protein catabolism
has_obo_namespace: biological_process
has_related_synonym: peptidolysis during cellular protein catabolic process
has_related_synonym: peptidolysis during cellular protein catabolism
has_related_synonym: proteolysis during cellular protein catabolic process
has_related_synonym: proteolysis during cellular protein catabolism
id: GO:0051603
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: proteolysis involved in cellular protein catabolic process
annotated property: definition
annotated target: The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
database_cross_reference: GOC:ai
database_cross_reference: GOC:dph
database_cross_reference: GOC:tb

protein maturation
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: Any process leading to the attainment of the full functional capacity of a protein.
has_obo_namespace: biological_process
id: GO:0051604
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pir
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: protein maturation
annotated property: definition
annotated target: Any process leading to the attainment of the full functional capacity of a protein.
database_cross_reference: GOC:ai

regulation of cell cycle
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: regulates
  some values from: biological_process
definition: Any process that modulates the rate or extent of progression through the cell cycle.
has_alternative_id: GO:0000074
database_cross_reference: Reactome:REACT_100159
database_cross_reference: Reactome:REACT_1006
database_cross_reference: Reactome:REACT_102418
database_cross_reference: Reactome:REACT_102475
database_cross_reference: Reactome:REACT_103468
database_cross_reference: Reactome:REACT_104523
database_cross_reference: Reactome:REACT_105454
database_cross_reference: Reactome:REACT_106237
database_cross_reference: Reactome:REACT_106324
database_cross_reference: Reactome:REACT_107424
database_cross_reference: Reactome:REACT_108578
database_cross_reference: Reactome:REACT_109244
database_cross_reference: Reactome:REACT_109507
database_cross_reference: Reactome:REACT_109584
database_cross_reference: Reactome:REACT_110774
database_cross_reference: Reactome:REACT_112480
database_cross_reference: Reactome:REACT_113569
database_cross_reference: Reactome:REACT_113990
database_cross_reference: Reactome:REACT_114323
database_cross_reference: Reactome:REACT_1944
database_cross_reference: Reactome:REACT_2119
database_cross_reference: Reactome:REACT_28091
database_cross_reference: Reactome:REACT_29213
database_cross_reference: Reactome:REACT_30490
database_cross_reference: Reactome:REACT_30836
database_cross_reference: Reactome:REACT_30859
database_cross_reference: Reactome:REACT_32077
database_cross_reference: Reactome:REACT_34285
database_cross_reference: Reactome:REACT_414
database_cross_reference: Reactome:REACT_80617
database_cross_reference: Reactome:REACT_81789
database_cross_reference: Reactome:REACT_82824
database_cross_reference: Reactome:REACT_83089
database_cross_reference: Reactome:REACT_83883
database_cross_reference: Reactome:REACT_87352
database_cross_reference: Reactome:REACT_88486
database_cross_reference: Reactome:REACT_89122
database_cross_reference: Reactome:REACT_91085
database_cross_reference: Reactome:REACT_92033
database_cross_reference: Reactome:REACT_93521
database_cross_reference: Reactome:REACT_93702
database_cross_reference: Reactome:REACT_95088
database_cross_reference: Reactome:REACT_96524
database_cross_reference: Reactome:REACT_97306
database_cross_reference: Reactome:REACT_97384
database_cross_reference: Reactome:REACT_98443
database_cross_reference: Reactome:REACT_99158
has_exact_synonym: cell cycle modulation
has_exact_synonym: cell cycle regulation
has_exact_synonym: control of cell cycle progression
has_exact_synonym: modulation of cell cycle progression
has_exact_synonym: regulation of cell cycle progression
has_exact_synonym: regulation of progression through cell cycle
has_obo_namespace: biological_process
has_related_synonym: cell cycle regulator
has_related_synonym: tumor suppressor
id: GO:0051726
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: regulation of cell cycle
annotated property: definition
annotated target: Any process that modulates the rate or extent of progression through the cell cycle.
database_cross_reference: GOC:ai
database_cross_reference: GOC:dph
database_cross_reference: GOC:tb

Inactivation of Myt1 kinase, Mus musculus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_100159

Polo-like kinase mediated events, Homo sapiens
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_1006

Polo-like kinase mediated events, Schizosaccharomyces pombe
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_102418

Inactivation of Myt1 kinase, Rattus norvegicus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_102475

Activation of Cdc25C, Drosophila melanogaster
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_103468

Inactivation of Wee1 kinase, Bos taurus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_104523

Polo-like kinase mediated events, Dictyostelium discoideum
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_105454

Polo-like kinase mediated events, Caenorhabditis elegans
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_106237

Activation of Cdc25C, Mus musculus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_106324

Inactivation of Myt1 kinase, Canis familiaris
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_107424

Inactivation of Myt1 kinase, Xenopus tropicalis
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_108578

Inactivation of Myt1 kinase, Schizosaccharomyces pombe
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_109244

Polo-like kinase mediated events, Taeniopygia guttata
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_109507

Polo-like kinase mediated events, Saccharomyces cerevisiae
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_109584

Inactivation of Myt1 kinase, Drosophila melanogaster
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_110774

Inactivation of Wee1 kinase, Dictyostelium discoideum
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_112480

Activation of Cdc25C, Saccharomyces cerevisiae
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_113569

Activation of Cdc25C, Schizosaccharomyces pombe
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_113990

Activation of Cdc25C, Caenorhabditis elegans
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_114323

Inactivation of Wee1 kinase, Homo sapiens
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_1944

Activation of Cdc25C, Homo sapiens
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_2119

Inactivation of Wee1 kinase, Canis familiaris
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_28091

Activation of Cdc25C, Rattus norvegicus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_29213

Inactivation of Myt1 kinase, Danio rerio
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_30490

Inactivation of Myt1 kinase, Bos taurus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_30836

Polo-like kinase mediated events, Gallus gallus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_30859

Inactivation of Myt1 kinase, Dictyostelium discoideum
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_32077

Activation of Cdc25C, Bos taurus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_34285

Inactivation of Myt1 kinase, Homo sapiens
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_414

Inactivation of Wee1 kinase, Xenopus tropicalis
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_80617

Polo-like kinase mediated events, Drosophila melanogaster
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_81789

Inactivation of Wee1 kinase, Rattus norvegicus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_82824

Inactivation of Myt1 kinase, Saccharomyces cerevisiae
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_83089

Polo-like kinase mediated events, Canis familiaris
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_83883

Polo-like kinase mediated events, Danio rerio
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_87352

Inactivation of Wee1 kinase, Taeniopygia guttata
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_88486

Activation of Cdc25C, Canis familiaris
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_89122

Inactivation of Wee1 kinase, Danio rerio
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_91085

Inactivation of Myt1 kinase, Caenorhabditis elegans
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_92033

Polo-like kinase mediated events, Mus musculus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_93521

Polo-like kinase mediated events, Rattus norvegicus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_93702

Inactivation of Wee1 kinase, Mus musculus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_95088

Activation of Cdc25C, Xenopus tropicalis
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_96524

Polo-like kinase mediated events, Bos taurus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_97306

Polo-like kinase mediated events, Xenopus tropicalis
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_97384

Inactivation of Wee1 kinase, Gallus gallus
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_98443

Inactivation of Wee1 kinase, Drosophila melanogaster
type: Axiom
annotated source: regulation of cell cycle
annotated property: database_cross_reference
annotated target: Reactome:REACT_99158

transmembrane transport
type: Class
subclass of: biological_process
definition: The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
database_cross_reference: Reactome:REACT_100480
database_cross_reference: Reactome:REACT_101577
database_cross_reference: Reactome:REACT_101877
database_cross_reference: Reactome:REACT_101975
database_cross_reference: Reactome:REACT_102348
database_cross_reference: Reactome:REACT_102897
database_cross_reference: Reactome:REACT_102974
database_cross_reference: Reactome:REACT_104555
database_cross_reference: Reactome:REACT_108243
database_cross_reference: Reactome:REACT_109832
database_cross_reference: Reactome:REACT_110770
database_cross_reference: Reactome:REACT_114546
database_cross_reference: Reactome:REACT_114763
database_cross_reference: Reactome:REACT_114890
database_cross_reference: Reactome:REACT_115378
database_cross_reference: Reactome:REACT_15480
database_cross_reference: Reactome:REACT_15518
database_cross_reference: Reactome:REACT_19118
database_cross_reference: Reactome:REACT_29093
database_cross_reference: Reactome:REACT_29184
database_cross_reference: Reactome:REACT_29635
database_cross_reference: Reactome:REACT_30969
database_cross_reference: Reactome:REACT_32055
database_cross_reference: Reactome:REACT_32223
database_cross_reference: Reactome:REACT_32423
database_cross_reference: Reactome:REACT_32713
database_cross_reference: Reactome:REACT_33571
database_cross_reference: Reactome:REACT_61245
database_cross_reference: Reactome:REACT_79086
database_cross_reference: Reactome:REACT_79921
database_cross_reference: Reactome:REACT_80022
database_cross_reference: Reactome:REACT_80510
database_cross_reference: Reactome:REACT_80848
database_cross_reference: Reactome:REACT_80977
database_cross_reference: Reactome:REACT_81024
database_cross_reference: Reactome:REACT_81153
database_cross_reference: Reactome:REACT_82725
database_cross_reference: Reactome:REACT_83770
database_cross_reference: Reactome:REACT_86135
database_cross_reference: Reactome:REACT_86409
database_cross_reference: Reactome:REACT_86576
database_cross_reference: Reactome:REACT_87124
database_cross_reference: Reactome:REACT_88059
database_cross_reference: Reactome:REACT_88521
database_cross_reference: Reactome:REACT_88894
database_cross_reference: Reactome:REACT_89376
database_cross_reference: Reactome:REACT_91272
database_cross_reference: Reactome:REACT_91803
database_cross_reference: Reactome:REACT_92006
database_cross_reference: Reactome:REACT_92624
database_cross_reference: Reactome:REACT_93747
database_cross_reference: Reactome:REACT_94160
database_cross_reference: Reactome:REACT_94393
database_cross_reference: Reactome:REACT_94944
database_cross_reference: Reactome:REACT_94972
database_cross_reference: Reactome:REACT_96633
database_cross_reference: Reactome:REACT_96636
database_cross_reference: Reactome:REACT_97365
database_cross_reference: Reactome:REACT_97867
database_cross_reference: Reactome:REACT_98509
database_cross_reference: Reactome:REACT_98716
database_cross_reference: Reactome:REACT_99579
database_cross_reference: Reactome:REACT_99829
has_exact_synonym: membrane transport
has_obo_namespace: biological_process
id: GO:0055085
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim pombe
in_subset: goslim yeast
comment: Transmembrane transport requires transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes.

Axiom
annotated source: transmembrane transport
annotated property: definition
annotated target: The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
database_cross_reference: GOC:dph
database_cross_reference: GOC:jid

SLC-mediated transmembrane transport, Taeniopygia guttata
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_100480

SLC-mediated transmembrane transport, Caenorhabditis elegans
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_101577

SLC-mediated transmembrane transport, Escherichia coli
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_101877

SLC-mediated transmembrane transport, Sus scrofa
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_101975

Transmembrane transport of small molecules, Staphylococcus aureus N315
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_102348

Transmembrane transport of small molecules, Caenorhabditis elegans
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_102897

SLC-mediated transmembrane transport, Canis familiaris
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_102974

SLC-mediated transmembrane transport, Xenopus tropicalis
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_104555

SLC-mediated transmembrane transport, Staphylococcus aureus N315
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_108243

Transmembrane transport of small molecules, Plasmodium falciparum
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_109832

ABC-family proteins mediated transport, Mus musculus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_110770

ABC-family proteins mediated transport, Staphylococcus aureus N315
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_114546

ABC-family proteins mediated transport, Escherichia coli
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_114763

ABC-family proteins mediated transport, Plasmodium falciparum
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_114890

ABC-family proteins mediated transport, Mycobacterium tuberculosis
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_115378

ABC-family proteins mediated transport, Homo sapiens
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_15480

Transmembrane transport of small molecules, Homo sapiens
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_15518

SLC-mediated transmembrane transport, Homo sapiens
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_19118

ABC-family proteins mediated transport, Taeniopygia guttata
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_29093

SLC-mediated transmembrane transport, Gallus gallus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_29184

Transmembrane transport of small molecules, Canis familiaris
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_29635

ABC-family proteins mediated transport, Canis familiaris
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_30969

Transmembrane transport of small molecules, Saccharomyces cerevisiae
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_32055

Transmembrane transport of small molecules, Rattus norvegicus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_32223

SLC-mediated transmembrane transport, Bos taurus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_32423

ABC-family proteins mediated transport, Sus scrofa
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_32713

SLC-mediated transmembrane transport, Danio rerio
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_33571

Transmembrane transport of small molecules, Bos taurus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_61245

SLC-mediated transmembrane transport, Plasmodium falciparum
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_79086

SLC-mediated transmembrane transport, Saccharomyces cerevisiae
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_79921

ABC-family proteins mediated transport, Bos taurus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_80022

ABC-family proteins mediated transport, Rattus norvegicus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_80510

ABC-family proteins mediated transport, Schizosaccharomyces pombe
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_80848

ABC-family proteins mediated transport, Caenorhabditis elegans
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_80977

Transmembrane transport of small molecules, Oryza sativa
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_81024

SLC-mediated transmembrane transport, Mus musculus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_81153

SLC-mediated transmembrane transport, Rattus norvegicus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_82725

Transmembrane transport of small molecules, Escherichia coli
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_83770

ABC-family proteins mediated transport, Oryza sativa
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_86135

Transmembrane transport of small molecules, Drosophila melanogaster
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_86409

Transmembrane transport of small molecules, Schizosaccharomyces pombe
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_86576

SLC-mediated transmembrane transport, Oryza sativa
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_87124

ABC-family proteins mediated transport, Xenopus tropicalis
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_88059

Transmembrane transport of small molecules, Taeniopygia guttata
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_88521

Transmembrane transport of small molecules, Gallus gallus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_88894

SLC-mediated transmembrane transport, Schizosaccharomyces pombe
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_89376

ABC-family proteins mediated transport, Arabidopsis thaliana
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_91272

SLC-mediated transmembrane transport, Mycobacterium tuberculosis
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_91803

Transmembrane transport of small molecules, Mycobacterium tuberculosis
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_92006

ABC-family proteins mediated transport, Gallus gallus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_92624

Transmembrane transport of small molecules, Dictyostelium discoideum
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_93747

Transmembrane transport of small molecules, Mus musculus
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_94160

ABC-family proteins mediated transport, Drosophila melanogaster
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_94393

ABC-family proteins mediated transport, Danio rerio
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_94944

SLC-mediated transmembrane transport, Dictyostelium discoideum
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_94972

Transmembrane transport of small molecules, Sus scrofa
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_96633

SLC-mediated transmembrane transport, Arabidopsis thaliana
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_96636

Transmembrane transport of small molecules, Arabidopsis thaliana
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_97365

ABC-family proteins mediated transport, Saccharomyces cerevisiae
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_97867

Transmembrane transport of small molecules, Xenopus tropicalis
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_98509

SLC-mediated transmembrane transport, Drosophila melanogaster
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_98716

Transmembrane transport of small molecules, Danio rerio
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_99579

ABC-family proteins mediated transport, Dictyostelium discoideum
type: Axiom
annotated source: transmembrane transport
annotated property: database_cross_reference
annotated target: Reactome:REACT_99829

nucleobase-containing small molecule metabolic process
type: Class
subclass of: biological_process
definition: The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
database_cross_reference: Reactome:REACT_100770
database_cross_reference: Reactome:REACT_105851
database_cross_reference: Reactome:REACT_107755
database_cross_reference: Reactome:REACT_107894
database_cross_reference: Reactome:REACT_116039
database_cross_reference: Reactome:REACT_1698
database_cross_reference: Reactome:REACT_28046
database_cross_reference: Reactome:REACT_29205
database_cross_reference: Reactome:REACT_29767
database_cross_reference: Reactome:REACT_31512
database_cross_reference: Reactome:REACT_33967
database_cross_reference: Reactome:REACT_77113
database_cross_reference: Reactome:REACT_78257
database_cross_reference: Reactome:REACT_82673
database_cross_reference: Reactome:REACT_82902
database_cross_reference: Reactome:REACT_82978
database_cross_reference: Reactome:REACT_83845
database_cross_reference: Reactome:REACT_86759
database_cross_reference: Reactome:REACT_90903
database_cross_reference: Reactome:REACT_96600
database_cross_reference: Reactome:REACT_97332
database_cross_reference: Reactome:REACT_99343
has_exact_synonym: nucleobase, nucleoside and nucleotide metabolism
has_obo_namespace: biological_process
has_related_synonym: nucleobase, nucleoside and nucleotide metabolic process
id: GO:0055086
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: definition
annotated target: The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
database_cross_reference: GOC:vw

Metabolism of nucleotides, Plasmodium falciparum
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_100770

Metabolism of nucleotides, Schizosaccharomyces pombe
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_105851

Metabolism of nucleotides, Mycobacterium tuberculosis
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_107755

Metabolism of nucleotides, Rattus norvegicus
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_107894

Nucleotide metabolism, Gallus gallus
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_116039

Metabolism of nucleotides, Homo sapiens
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_1698

Metabolism of nucleotides, Drosophila melanogaster
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_28046

Metabolism of nucleotides, Dictyostelium discoideum
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_29205

Metabolism of nucleotides, Saccharomyces cerevisiae
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_29767

Metabolism of nucleotides, Sus scrofa
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_31512

Metabolism of nucleotides, Mus musculus
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_33967

Metabolism of nucleotides, Taeniopygia guttata
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_77113

Metabolism of nucleotides, Staphylococcus aureus N315
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_78257

Metabolism of nucleotides, Caenorhabditis elegans
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_82673

Metabolism of nucleotides, Canis familiaris
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_82902

Metabolism of nucleotides, Escherichia coli
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_82978

Metabolism of nucleotides, Bos taurus
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_83845

Metabolism of nucleotides, Oryza sativa
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_86759

Metabolism of nucleotides, Gallus gallus
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_90903

Metabolism of nucleotides, Danio rerio
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_96600

Metabolism of nucleotides, Arabidopsis thaliana
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_97332

Metabolism of nucleotides, Xenopus tropicalis
type: Axiom
annotated source: nucleobase-containing small molecule metabolic process
annotated property: database_cross_reference
annotated target: Reactome:REACT_99343

membrane fusion
type: Class
subclass of: biological_process
definition: The membrane organization process that joins two lipid bilayers to form a single membrane.
created by: dph
creation date: 2010-02-08T02:48:06Z
has_alternative_id: GO:0006944
database_cross_reference: Wikipedia:Lipid_bilayer_fusion
has_exact_synonym: cellular membrane fusion
has_obo_namespace: biological_process
id: GO:0061025
in_subset: goslim yeast

Axiom
annotated source: membrane fusion
annotated property: definition
annotated target: The membrane organization process that joins two lipid bilayers to form a single membrane.
database_cross_reference: GOC:dph
database_cross_reference: GOC:tb

protein complex biogenesis
type: Class
subclass of: biological_process
definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex.
has_exact_synonym: protein complex biogenesis and assembly
has_obo_namespace: biological_process
id: GO:0070271
in_subset: goslim yeast
in_subset: gosubset prok
comment: This classification should should only be used for complexes where synthesis of some non-protein component is necessary for assembly.

Axiom
annotated source: protein complex biogenesis
annotated property: definition
annotated target: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex.
database_cross_reference: GOC:mah

Axiom
annotated source: protein complex biogenesis
annotated property: has_exact_synonym
annotated target: protein complex biogenesis and assembly
database_cross_reference: GOC:mah

protein modification by small protein conjugation or removal
type: Class
subclass of: biological_process
definition: A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
created by: midori
creation date: 2009-05-11T02:54:03Z
has_obo_namespace: biological_process
id: GO:0070647
in_subset: goslim pombe
in_subset: goslim yeast

Axiom
annotated source: protein modification by small protein conjugation or removal
annotated property: definition
annotated target: A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
database_cross_reference: GOC:mah

organelle assembly
type: Class
subclass of: biological_process
subclass of: Restriction
  on property: part of
  some values from: biological_process
definition: The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
created by: midori
creation date: 2009-09-15T03:00:51Z
has_obo_namespace: biological_process
id: GO:0070925
in_subset: goslim yeast

Axiom
annotated source: organelle assembly
annotated property: definition
annotated target: The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
database_cross_reference: GOC:mah

cell wall organization or biogenesis
type: Class
subclass of: biological_process
definition: A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.
created by: midori
creation date: 2010-01-13T03:19:38Z
has_alternative_id: GO:0070882
has_exact_synonym: cell wall organisation or biogenesis
has_exact_synonym: cell wall organization or biogenesis at cellular level
has_exact_synonym: cellular cell wall organisation or biogenesis
has_exact_synonym: cellular cell wall organization or biogenesis
has_obo_namespace: biological_process
id: GO:0071554
in_subset: goslim chembl
in_subset: goslim generic
in_subset: goslim metagenomics
in_subset: goslim pombe
in_subset: goslim yeast
in_subset: gosubset prok

Axiom
annotated source: cell wall organization or biogenesis
annotated property: definition
annotated target: A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.
database_cross_reference: GOC:mah

Axiom
annotated source: cell wall organization or biogenesis
annotated property: has_exact_synonym
annotated target: cell wall organisation or biogenesis
database_cross_reference: GOC:mah

Axiom
annotated source: cell wall organization or biogenesis
annotated property: has_exact_synonym
annotated target: cell wall organization or biogenesis at cellular level
database_cross_reference: GOC:mah

Axiom
annotated source: cell wall organization or biogenesis
annotated property: has_exact_synonym
annotated target: cellular cell wall organisation or biogenesis
database_cross_reference: GOC:mah